Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on: January 30,2024

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on:January 30,2024

AZD6738 found to slow some types of children's tumor growth in mouse models

by Bob Yirka , Medical XpressCredit: CC0 Public Domain(Medical Xpress)—A team of researchers from the U.S., Germany and Japan has found that the chemical AZD6738 was able to slow some childhood type t

Updated on: April 22,2024

AZD6738 found to slow some types of children's tumor growth in mouse models

by Bob Yirka , Medical XpressCredit: CC0 Public Domain(Medical Xpress)—A team of researchers from the U.S., Germany and Japan has found that the chemical AZD6738 was able to slow some childhood type t

Updated on:April 22,2024

Studies give new insights on immunotherapy in elderly patients with advanced NSCLC

by European Society for Medical OncologyTwo studies to be reported at ELCC 2019 provide new insights on the efficacy and safety of immunotherapy in elderly patients with advanced non-small-cell l

Updated on: May 31,2024

Studies give new insights on immunotherapy in elderly patients with advanced NSCLC

by European Society for Medical OncologyTwo studies to be reported at ELCC 2019 provide new insights on the efficacy and safety of immunotherapy in elderly patients with advanced non-small-cell l

Updated on:May 31,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on: March 30,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on:March 30,2024

Living close to urban green spaces is associated with decreased breast cancer risk

by Barcelona Institute for Global Health (ISGlobal)Credit: CC0 Public DomainAn increasing number of studies are reporting the health benefits of contact with urban green spaces. A new study from the B

Updated on: April 07,2024

Living close to urban green spaces is associated with decreased breast cancer risk

by Barcelona Institute for Global Health (ISGlobal)Credit: CC0 Public DomainAn increasing number of studies are reporting the health benefits of contact with urban green spaces. A new study from the B

Updated on:April 07,2024

Rethinking existing method opens new doors for cancer diagnostics

by Osaka UniversityOperating principle of single-molecule quantum sequencing. Credit: Osaka UniversityAll diseases have a genetic component. Advances in understanding the genetic mechanisms behin

Updated on: April 07,2024

Rethinking existing method opens new doors for cancer diagnostics

by Osaka UniversityOperating principle of single-molecule quantum sequencing. Credit: Osaka UniversityAll diseases have a genetic component. Advances in understanding the genetic mechanisms behin

Updated on:April 07,2024

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati

Updated on: February 23,2024

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati

Updated on:February 23,2024

Researchers search for solutions to 'invisible threat' that affects cancer care workers

by University of MichiganVisual abstracts describes the study's findings. Credit: University of Michigan School of NursingChemotherapy drugs are lifesaving to cancer patients, but these toxic

Updated on: June 01,2024

Researchers search for solutions to 'invisible threat' that affects cancer care workers

by University of MichiganVisual abstracts describes the study's findings. Credit: University of Michigan School of NursingChemotherapy drugs are lifesaving to cancer patients, but these toxic

Updated on:June 01,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on: January 02,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on:January 02,2024

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Updated on: January 30,2024

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Updated on:January 30,2024