Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Updated on: January 03,2024

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Updated on:January 03,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on: May 27,2024

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on:May 27,2024

Generating large numbers of universal immune cells could transform cancer immunotherapy

by Agency for Science, Technology and Research (A*STAR), SingaporeA novel method to generate natural killer cells from peripheral blood cell-derived stem cells may transform immunotherapies for d

Updated on: March 12,2024

Generating large numbers of universal immune cells could transform cancer immunotherapy

by Agency for Science, Technology and Research (A*STAR), SingaporeA novel method to generate natural killer cells from peripheral blood cell-derived stem cells may transform immunotherapies for d

Updated on:March 12,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on: January 02,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on:January 02,2024

Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies

byStanford University Medical CenterA machine-learning framework for large-scale identification and validation of sarcoma cell states and ecosystems. Credit:Nature Cancer(2024). DOI:

Updated on: March 30,2024

Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies

byStanford University Medical CenterA machine-learning framework for large-scale identification and validation of sarcoma cell states and ecosystems. Credit:Nature Cancer(2024). DOI:

Updated on:March 30,2024

Salmonella exposure a risk for colon cancer, finds study

byUniversity of Illinois at ChicagoGraphical Abstract. Credit:Cell Reports Medicine(2022). DOI: 10.1016/j.xcrm.2022.100852A new study published in the journalCell Reports Medic

Updated on: January 23,2024

Salmonella exposure a risk for colon cancer, finds study

byUniversity of Illinois at ChicagoGraphical Abstract. Credit:Cell Reports Medicine(2022). DOI: 10.1016/j.xcrm.2022.100852A new study published in the journalCell Reports Medic

Updated on:January 23,2024

No radiotherapy an option for older breast cancer patients, study shows

by University of EdinburghCredit: Unsplash/CC0 Public DomainRadiotherapy does not improve survival rates in older patients with early breast cancer, new research suggests.The addition of radiothe

Updated on: February 18,2024

No radiotherapy an option for older breast cancer patients, study shows

by University of EdinburghCredit: Unsplash/CC0 Public DomainRadiotherapy does not improve survival rates in older patients with early breast cancer, new research suggests.The addition of radiothe

Updated on:February 18,2024

One sigmoidoscopy significantly reduces long-term CRC incidence in both men and women

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainA pooled analysis evaluating the 15-year effect of sigmoidoscopies has found that receiving one sigmoidoscopy significantly reduc

Updated on: January 30,2024

One sigmoidoscopy significantly reduces long-term CRC incidence in both men and women

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainA pooled analysis evaluating the 15-year effect of sigmoidoscopies has found that receiving one sigmoidoscopy significantly reduc

Updated on:January 30,2024

Mailing colorectal cancer screening kit found effective, regardless of financial incentive

by Perelman School of Medicine at the University of PennsylvaniaCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Colorectal cancer is the second deadliest cancer i

Updated on: May 09,2024

Mailing colorectal cancer screening kit found effective, regardless of financial incentive

by Perelman School of Medicine at the University of PennsylvaniaCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Colorectal cancer is the second deadliest cancer i

Updated on:May 09,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on: June 22,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on:June 22,2024

Placebo pill eases cancer-related fatigue in study

by Alan MozesPatients with advanced cancer often suffer crippling fatigue, but there has been little in the way of relief for them as they battle their disease.Now, a new investigation may have landed

Updated on: March 06,2024

Placebo pill eases cancer-related fatigue in study

by Alan MozesPatients with advanced cancer often suffer crippling fatigue, but there has been little in the way of relief for them as they battle their disease.Now, a new investigation may have landed

Updated on:March 06,2024