Gut bacteria engineered to act as tumor GPS for immunotherapies

byDana-Farber Cancer InstituteBacteria displaying hDR18 enhance anti-tumor responses of MSLN-CAR NK cells. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-024-02418-6Immunothe

Updated on: October 10,2024

Gut bacteria engineered to act as tumor GPS for immunotherapies

byDana-Farber Cancer InstituteBacteria displaying hDR18 enhance anti-tumor responses of MSLN-CAR NK cells. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-024-02418-6Immunothe

Updated on:October 10,2024

New test predicts chance of living more than a year on targeted breast cancer treatment

by Institute of Cancer ResearchBreast cancer cells stained for DNA (red), NFkB (green), and a reactive oxygen species probe (blue). Credit: Julia Sero / the ICR, 2011A new test could pick out wom

Updated on: May 23,2024

New test predicts chance of living more than a year on targeted breast cancer treatment

by Institute of Cancer ResearchBreast cancer cells stained for DNA (red), NFkB (green), and a reactive oxygen species probe (blue). Credit: Julia Sero / the ICR, 2011A new test could pick out wom

Updated on:May 23,2024

Incoming New Zealand govt to abandon anti-smoking laws

Credit: CC0 Public DomainNew Zealand's incoming conservative government will jettison world-leading measures to stub out smoking, new Prime Minister Christopher Luxon confirmed Monday, in a move d

Updated on: March 06,2024

Incoming New Zealand govt to abandon anti-smoking laws

Credit: CC0 Public DomainNew Zealand's incoming conservative government will jettison world-leading measures to stub out smoking, new Prime Minister Christopher Luxon confirmed Monday, in a move d

Updated on:March 06,2024

Researchers create novel compound targeting melanoma cells

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0An international team of re

Updated on: June 24,2024

Researchers create novel compound targeting melanoma cells

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0An international team of re

Updated on:June 24,2024

Hypofractioned post-prostatectomy radiotherapy new acceptable practice standard based on NRG Oncology trial findings

by NRG OncologyResults from the Phase III NRG Oncology NRG-GU003 clinical trial comparing hypofractioned post-prostatectomy radiotherapy (HYPORT) to conventionally fractioned post-prostatectomy radiot

Updated on: March 30,2024

Hypofractioned post-prostatectomy radiotherapy new acceptable practice standard based on NRG Oncology trial findings

by NRG OncologyResults from the Phase III NRG Oncology NRG-GU003 clinical trial comparing hypofractioned post-prostatectomy radiotherapy (HYPORT) to conventionally fractioned post-prostatectomy radiot

Updated on:March 30,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on: January 02,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on:January 02,2024

Biological pathways provide evidence for how to overcome barriers limiting cancer immunotherapies

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at UNC Lineberger Comprehensive Cancer Center have found a possible way to overcome barriers that block

Updated on: January 04,2024

Biological pathways provide evidence for how to overcome barriers limiting cancer immunotherapies

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers at UNC Lineberger Comprehensive Cancer Center have found a possible way to overcome barriers that block

Updated on:January 04,2024

Costs of $259,324 incurred by adolescent, young adult cancer survivors

by Elana GotkineAdolescent and young adult (AYA) cancer survivors incur costs of $259,324 over their lifetime, according to a study published online Feb. 24 in theJournal of Clinical Oncology.Su

Updated on: January 02,2024

Costs of $259,324 incurred by adolescent, young adult cancer survivors

by Elana GotkineAdolescent and young adult (AYA) cancer survivors incur costs of $259,324 over their lifetime, according to a study published online Feb. 24 in theJournal of Clinical Oncology.Su

Updated on:January 02,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on: April 01,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on:April 01,2024

Researchers complete largest genomic analysis of Merkel cell carcinoma patients

by H. Lee Moffitt Cancer Center & Research InstituteCredit: CC0 Public DomainMerkel cell carcinoma (MCC) is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each

Updated on: June 04,2024

Researchers complete largest genomic analysis of Merkel cell carcinoma patients

by H. Lee Moffitt Cancer Center & Research InstituteCredit: CC0 Public DomainMerkel cell carcinoma (MCC) is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each

Updated on:June 04,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on: June 22,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on:June 22,2024

Review covers progress in immunotherapy for esophageal cancer

by Cactus CommunicationsMultiple ongoing clinical trials are being conducted to test the potential of ICIs as an adjuvant therapy for resectable esophageal cancer. The results of these trials could ce

Updated on: January 22,2024

Review covers progress in immunotherapy for esophageal cancer

by Cactus CommunicationsMultiple ongoing clinical trials are being conducted to test the potential of ICIs as an adjuvant therapy for resectable esophageal cancer. The results of these trials could ce

Updated on:January 22,2024