NXC-201 Demonstrates Feasibility of BCMA-Directed CAR T-Cell Therapy in Relapsed/Refractory AL

September 30, 2023Ryan Scotthe novel anti-BCMA CAR T-cell therapy NXC-201 displayed safety and elicited hematologic and organ responses in patients with relapsed/refractory amyloid light chain amyloid

Updated on: October 24,2023

NXC-201 Demonstrates Feasibility of BCMA-Directed CAR T-Cell Therapy in Relapsed/Refractory AL

September 30, 2023Ryan Scotthe novel anti-BCMA CAR T-cell therapy NXC-201 displayed safety and elicited hematologic and organ responses in patients with relapsed/refractory amyloid light chain amyloid

Updated on:October 24,2023

Researchers surprised by high levels of alcohol consumption among cancer survivors

by National Comprehensive Cancer NetworkCredit: CC0 Public DomainNew research in the January 2020 issue ofJNCCN—Journal of the National Comprehensive Cancer Networkuses data from the Natio

Updated on: December 20,2023

Researchers surprised by high levels of alcohol consumption among cancer survivors

by National Comprehensive Cancer NetworkCredit: CC0 Public DomainNew research in the January 2020 issue ofJNCCN—Journal of the National Comprehensive Cancer Networkuses data from the Natio

Updated on:December 20,2023

Pharmacotyping of childhood leukemia provides a blueprint for 'true precision medicine'

bySt. Jude Children's Research HospitalWenjian Yang, Shawn Lee, MBBS, and Jun J. Yang, PhD, recently published a comprehensive study pharmacotyping childhood leukemia. Credit: St. Jude Child

Updated on: December 21,2023

Pharmacotyping of childhood leukemia provides a blueprint for 'true precision medicine'

bySt. Jude Children's Research HospitalWenjian Yang, Shawn Lee, MBBS, and Jun J. Yang, PhD, recently published a comprehensive study pharmacotyping childhood leukemia. Credit: St. Jude Child

Updated on:December 21,2023

More Evidence Gene Therapy Might Cure Sickle Cell Disease

By Cara MurezHealthDay ReporterMONDAY, June 12, 2023 (HealthDay News) -- A clinical trial that’s attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and succe

Updated on: October 12,2023

More Evidence Gene Therapy Might Cure Sickle Cell Disease

By Cara MurezHealthDay ReporterMONDAY, June 12, 2023 (HealthDay News) -- A clinical trial that’s attempting to discover a cure for sickle cell disease has found a new gene therapy to be safe and succe

Updated on:October 12,2023

Trial supports radiotherapy and cisplatin remaining as the standard of care for p16+ oropharyngeal cancer

by NRG OncologyCredit: Pixabay/CC0 Public DomainThe NRG Oncology NRG-HN005 phase II/III clinical trial has not met the non-inferiority criteria to proceed to the phase III portion of the study. The ph

Updated on: October 21,2024

Trial supports radiotherapy and cisplatin remaining as the standard of care for p16+ oropharyngeal cancer

by NRG OncologyCredit: Pixabay/CC0 Public DomainThe NRG Oncology NRG-HN005 phase II/III clinical trial has not met the non-inferiority criteria to proceed to the phase III portion of the study. The ph

Updated on:October 21,2024

Drug development in stem cell-derived liver organoid models

To ensure that new drugs are effective and have as little toxicity as possible, they first need to be tested in model systems before entering clinical trials. In this Q&A, Dr Takanori Takebe outli

Updated on: November 01,2023

Drug development in stem cell-derived liver organoid models

To ensure that new drugs are effective and have as little toxicity as possible, they first need to be tested in model systems before entering clinical trials. In this Q&A, Dr Takanori Takebe outli

Updated on:November 01,2023

Intensity of Consolidation Pre-Transplant Shows No Difference in Outcomes in Older AML

September 7, 2023Caroline SeymourNo difference in relapse-free survival or non–relapse mortality was seen with intensive vs non-intensive consolidation chemotherapy regimens prior to allogeneic hemato

Updated on: October 11,2023

Intensity of Consolidation Pre-Transplant Shows No Difference in Outcomes in Older AML

September 7, 2023Caroline SeymourNo difference in relapse-free survival or non–relapse mortality was seen with intensive vs non-intensive consolidation chemotherapy regimens prior to allogeneic hemato

Updated on:October 11,2023

Luspatercept Provides Frontline Alternative to ESAs For Lower-Risk MDS and Anemia

September 21, 2023Courtney FlahertyUwe Platzbecker, MD, discusses the efficacy and safety data from the COMMANDS trial that supported the approval, and the next steps planned for luspatercept’s invest

Updated on: October 11,2023

Luspatercept Provides Frontline Alternative to ESAs For Lower-Risk MDS and Anemia

September 21, 2023Courtney FlahertyUwe Platzbecker, MD, discusses the efficacy and safety data from the COMMANDS trial that supported the approval, and the next steps planned for luspatercept’s invest

Updated on:October 11,2023

Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainWhy do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop t

Updated on: January 08,2024

Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainWhy do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop t

Updated on:January 08,2024

New antibody may offer effective drug treatment for breast cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks. With further development, the antibody

Updated on: October 31,2023

New antibody may offer effective drug treatment for breast cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks. With further development, the antibody

Updated on:October 31,2023

IMNN-001 Plus Neoadjuvant Chemotherapy Improves PFS in Advanced Ovarian Cancer

September 28, 2023Chris RyanTreatment with the interleukin-12 gene-mediated immunotherapy IMNN-001 in combination with neoadjuvant platinum chemotherapy led to an improvement in progression-free survi

Updated on: October 10,2023

IMNN-001 Plus Neoadjuvant Chemotherapy Improves PFS in Advanced Ovarian Cancer

September 28, 2023Chris RyanTreatment with the interleukin-12 gene-mediated immunotherapy IMNN-001 in combination with neoadjuvant platinum chemotherapy led to an improvement in progression-free survi

Updated on:October 10,2023

Silent cancers: Here's what you need to know when there are no obvious symptoms

by Justin Stebbing,The ConversationCredit: Pixabay/CC0 Public DomainThe recent revelations about the Princess of Wales'scancer diagnosishighlight a crucial aspect of cancer detec

Updated on: April 06,2024

Silent cancers: Here's what you need to know when there are no obvious symptoms

by Justin Stebbing,The ConversationCredit: Pixabay/CC0 Public DomainThe recent revelations about the Princess of Wales'scancer diagnosishighlight a crucial aspect of cancer detec

Updated on:April 06,2024