Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on: July 02,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on:July 02,2024

Researchers develop 'on-demand' whole tumor cell vaccine against cancer

by Chinese Academy of SciencesStrategy of using photothermal nanoparticle-based whole tumor cell vaccine (LN-TCV) for on-demand near-infrared (NIR) manipulation of immune responses against cancer

Updated on: February 18,2024

Researchers develop 'on-demand' whole tumor cell vaccine against cancer

by Chinese Academy of SciencesStrategy of using photothermal nanoparticle-based whole tumor cell vaccine (LN-TCV) for on-demand near-infrared (NIR) manipulation of immune responses against cancer

Updated on:February 18,2024

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Updated on: January 22,2024

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Updated on:January 22,2024

Researchers discover a molecule that helps pancreas cells mature and limits tumor formation

by The Spanish National Cancer Research CentrePancreatic acinar cells undergoing inflammation. Credit: / Isidoro Cobo. CNIOThe pancreas, located behind the stomach, manages the energy supply in o

Updated on: February 23,2024

Researchers discover a molecule that helps pancreas cells mature and limits tumor formation

by The Spanish National Cancer Research CentrePancreatic acinar cells undergoing inflammation. Credit: / Isidoro Cobo. CNIOThe pancreas, located behind the stomach, manages the energy supply in o

Updated on:February 23,2024

Researchers identify genes that cause rare hidden cancer

by Garvan Institute of Medical ResearchIHC staining of human sarcoma cells (myxoid liposarcoma). Credit: Garvan Institute of Medical ResearchSeveral genes that cause sarcoma have been identified

Updated on: February 23,2024

Researchers identify genes that cause rare hidden cancer

by Garvan Institute of Medical ResearchIHC staining of human sarcoma cells (myxoid liposarcoma). Credit: Garvan Institute of Medical ResearchSeveral genes that cause sarcoma have been identified

Updated on:February 23,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on: January 30,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on:January 30,2024

Researchers find epigenetic loss that changes how cells obtain energy from cancer

by University of BarcelonaThe researchers Margalida Rosselló-Tortella, Manel Esteller and Pere Llinàs-Arias. Credit: UNIVERSITY OF BARCELONAIt has been known for decades that cancer cells have an

Updated on: June 24,2024

Researchers find epigenetic loss that changes how cells obtain energy from cancer

by University of BarcelonaThe researchers Margalida Rosselló-Tortella, Manel Esteller and Pere Llinàs-Arias. Credit: UNIVERSITY OF BARCELONAIt has been known for decades that cancer cells have an

Updated on:June 24,2024

Docs should consider a patient's weight before prescribing new chemotherapy drugs

by Sharon Parmet,University of Illinois at ChicagoAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA new class of cancer drugs just now

Updated on: May 13,2024

Docs should consider a patient's weight before prescribing new chemotherapy drugs

by Sharon Parmet,University of Illinois at ChicagoAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA new class of cancer drugs just now

Updated on:May 13,2024

Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

by Harvard Medical SchoolA 3D reconstruction of colorectal cancer revealed that what was once thought to be 2D mucin pools with clusters of cancer cells floating inside is actually a complex and

Updated on: February 24,2024

Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

by Harvard Medical SchoolA 3D reconstruction of colorectal cancer revealed that what was once thought to be 2D mucin pools with clusters of cancer cells floating inside is actually a complex and

Updated on:February 24,2024

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on: February 18,2024

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on:February 18,2024

Researchers examine the metabolic effects of an oral blood cancer drug

by The Mount Sinai HospitalCredit: CC0 Public DomainA popular cancer drug is associated with significant weight gain and increased systolic blood pressure, researchers from the Icahn School of Me

Updated on: June 15,2024

Researchers examine the metabolic effects of an oral blood cancer drug

by The Mount Sinai HospitalCredit: CC0 Public DomainA popular cancer drug is associated with significant weight gain and increased systolic blood pressure, researchers from the Icahn School of Me

Updated on:June 15,2024

Researchers help identify mechanisms by which multiple myeloma escapes targeted immunotherapy

by University of Miami Leonard M. Miller School of MedicineScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDRese

Updated on: February 20,2024

Researchers help identify mechanisms by which multiple myeloma escapes targeted immunotherapy

by University of Miami Leonard M. Miller School of MedicineScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDRese

Updated on:February 20,2024