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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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How colliding genetic processes drive aggressive cancers

How colliding genetic processes drive aggressive cancers

byUniversity of Chicago Medical CenterLoss of CDK12 promotes large TD formation. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00848-4Cancer researchers at the University of Ch

How colliding genetic processes drive aggressive cancers

byUniversity of Chicago Medical CenterLoss of CDK12 promotes large TD formation. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00848-4Cancer researchers at the University of Ch
New drug, WNTinib, delays tumor growth and improves survival in mouse models of children's liver cancer

New drug, WNTinib, delays tumor growth and improves survival in mouse models of children's liver cancer

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainA new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of

New drug, WNTinib, delays tumor growth and improves survival in mouse models of children's liver cancer

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainA new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of
Salmonella research unlocks the potential of bacteria to treat bowel cancer

Salmonella research unlocks the potential of bacteria to treat bowel cancer

byUniversity of GlasgowTILs from mice treated with Salmonella are functionally defective. Credit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00159-2Fighting bowel cancer w

Salmonella research unlocks the potential of bacteria to treat bowel cancer

byUniversity of GlasgowTILs from mice treated with Salmonella are functionally defective. Credit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00159-2Fighting bowel cancer w
Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

byAmerican Society of HematologyCredit: Pixabay/CC0 Public DomainIn the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T

Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

byAmerican Society of HematologyCredit: Pixabay/CC0 Public DomainIn the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T
Drug improves effectiveness of radiation for lung cancer that has spread to the brain

Drug improves effectiveness of radiation for lung cancer that has spread to the brain

by Tim Tedeschi,University of CincinnatiActivation of GABA(A) receptors triggers cell depolarization and death. Credit:Cancers(2024). DOI: 10.3390/cancers16183167In new research, a t

Drug improves effectiveness of radiation for lung cancer that has spread to the brain

by Tim Tedeschi,University of CincinnatiActivation of GABA(A) receptors triggers cell depolarization and death. Credit:Cancers(2024). DOI: 10.3390/cancers16183167In new research, a t
Editorial: Genotype matters—tailored screening for germline CHEK2 variants

Editorial: Genotype matters—tailored screening for germline CHEK2 variants

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA recent editorial was published inOncotarget, titled "Genotype matters: Personalized screening recommendations for germline CHEK2 var

Editorial: Genotype matters—tailored screening for germline CHEK2 variants

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA recent editorial was published inOncotarget, titled "Genotype matters: Personalized screening recommendations for germline CHEK2 var
An ancient signaling pathway and 20 years of research offer hope for rare cancer

An ancient signaling pathway and 20 years of research offer hope for rare cancer

byPeter MacCallum Cancer CentreCredit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00217-3Researchers at Peter Mac are using their knowledge of an ancient signaling pathway to find ne

An ancient signaling pathway and 20 years of research offer hope for rare cancer

byPeter MacCallum Cancer CentreCredit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00217-3Researchers at Peter Mac are using their knowledge of an ancient signaling pathway to find ne
A new screening tool improves liver cancer detection

A new screening tool improves liver cancer detection

by Jordan Shaked,Yale UniversityTen-year risk of hepatocellular carcinoma (HCC). Credit:JAMA Network Open(2024). DOI: 10.1001/jamanetworkopen.2024.43608Hepatocellular carcinoma, a ty

A new screening tool improves liver cancer detection

by Jordan Shaked,Yale UniversityTen-year risk of hepatocellular carcinoma (HCC). Credit:JAMA Network Open(2024). DOI: 10.1001/jamanetworkopen.2024.43608Hepatocellular carcinoma, a ty
Updated colorectal cancer screening effective for adults 45–50, study suggests

Updated colorectal cancer screening effective for adults 45–50, study suggests

byKaiser PermanenteCredit: Pixabay/CC0 Public DomainThe updated national colorectal cancer screening guidelines that recommend screening begin at age 45—rather than 50—can benefit younger adults

Updated colorectal cancer screening effective for adults 45–50, study suggests

byKaiser PermanenteCredit: Pixabay/CC0 Public DomainThe updated national colorectal cancer screening guidelines that recommend screening begin at age 45—rather than 50—can benefit younger adults
Immunotherapy shows potential to treat deadly thyroid cancer

Immunotherapy shows potential to treat deadly thyroid cancer

by Olivia Dimmer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainA type of immunotherapy appears to be effective in treating a deadly subset of thyroid cancer, according to the results o

Immunotherapy shows potential to treat deadly thyroid cancer

by Olivia Dimmer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainA type of immunotherapy appears to be effective in treating a deadly subset of thyroid cancer, according to the results o
Engineered receptors help the immune system home in on cancer

Engineered receptors help the immune system home in on cancer

byUniversity of California, San FranciscoCredit: CC0 Public DomainMost cancer treatments—from chemotherapies to engineered immune cells—have a host of side effects, in large part because they af

Engineered receptors help the immune system home in on cancer

byUniversity of California, San FranciscoCredit: CC0 Public DomainMost cancer treatments—from chemotherapies to engineered immune cells—have a host of side effects, in large part because they af
Precision breast cancer trial shows improved treatment by tumor subtype

Precision breast cancer trial shows improved treatment by tumor subtype

byUniversity of California, San FranciscoEfficacy of Dato-DXd + durvalumab treatment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03267-1Despite recent advances in the trea

Precision breast cancer trial shows improved treatment by tumor subtype

byUniversity of California, San FranciscoEfficacy of Dato-DXd + durvalumab treatment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03267-1Despite recent advances in the trea