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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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New research casts doubt on role of fungus in driving pancreatic cancer

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu
New immunotherapy targeting tumor macrophages to tackle lung cancer

New immunotherapy targeting tumor macrophages to tackle lung cancer

by Germans Trias i Pujol Research InstituteRImAb modifies the intratumoral myeloid cell compartment in a mouse model of LLC. a) Myeloid cell gating classification using the expression of surface marke

New immunotherapy targeting tumor macrophages to tackle lung cancer

by Germans Trias i Pujol Research InstituteRImAb modifies the intratumoral myeloid cell compartment in a mouse model of LLC. a) Myeloid cell gating classification using the expression of surface marke
Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia

by University of Chicago Medical Center5-AZA-sensitive and 5-AZA-resistant leukemia cells have distinctly different chromatin structures. Credit: Jason ChengDrug resistance is a major obstacle to

Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia

by University of Chicago Medical Center5-AZA-sensitive and 5-AZA-resistant leukemia cells have distinctly different chromatin structures. Credit: Jason ChengDrug resistance is a major obstacle to
Researchers key to advance care planning with cancer clinical trial patients

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P
Researchers find genetic pathways to individualized treatment for advanced prostate cancer

Researchers find genetic pathways to individualized treatment for advanced prostate cancer

by Mayo ClinicCredit: Mayo ClinicResearchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced pros

Researchers find genetic pathways to individualized treatment for advanced prostate cancer

by Mayo ClinicCredit: Mayo ClinicResearchers at Mayo Clinic Center for Individualized Medicine have uncovered genetic clues to why tumors resist a specific therapy used for treating advanced pros
Leukemia spread fueled by messenger particles, shows study

Leukemia spread fueled by messenger particles, shows study

byKing Abdullah University of Science and TechnologyMass spectrometry analysis reveals HSPCs-derived exosomes are enriched in proteins involved in adhesion and migration. Proteomics analysis of

Leukemia spread fueled by messenger particles, shows study

byKing Abdullah University of Science and TechnologyMass spectrometry analysis reveals HSPCs-derived exosomes are enriched in proteins involved in adhesion and migration. Proteomics analysis of
Tumors form temporary structures to avoid immunotherapy treatments

Tumors form temporary structures to avoid immunotherapy treatments

byeLifeTumor-reactive T cells induce transient cell-in-cell structure. (A) Mean percentage of cell-in-cell tumor formations following incubation of B16F10 cells with immune cells (n=4). (B) Repr

Tumors form temporary structures to avoid immunotherapy treatments

byeLifeTumor-reactive T cells induce transient cell-in-cell structure. (A) Mean percentage of cell-in-cell tumor formations following incubation of B16F10 cells with immune cells (n=4). (B) Repr
Tumor mutations may predict response to immunotherapy

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when
Lung cancer screening implementation guide developed

Lung cancer screening implementation guide developed

(HealthDay)—The American Lung Association and the American Thoracic Society have established a website to guide implementation of lung cancer screening, according to an editorial published in the Nov.

Lung cancer screening implementation guide developed

(HealthDay)—The American Lung Association and the American Thoracic Society have established a website to guide implementation of lung cancer screening, according to an editorial published in the Nov.
Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne

Research identifies a new drug candidate to starve and suffocate breast cancer cell stem growth

by University of SalfordMichael P. Lisanti. Credit: University of SalfordScientists have identified a new drug candidate that is able starve and suffocate cancer stem cells, paving the way for ne
Discovery could lead to new drugs to block protein that fuels bowel cancer

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc
A chemistry pioneer works to improve a flawed test for a common cancer

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a