Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on: February 24,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on:February 24,2024

Research team reveals mechanisms at work in progression of pancreatic cysts to pancreatic cancer

by University of California, San FranciscoPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cysts have gained substantial

Updated on: January 30,2024

Research team reveals mechanisms at work in progression of pancreatic cysts to pancreatic cancer

by University of California, San FranciscoPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cysts have gained substantial

Updated on:January 30,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on: February 03,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on:February 03,2024

Study fingers new player in cancer immunity

by Harvard Medical SchoolKiller T cells surround a cancer cell. Credit: NIHThe immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time res

Updated on: May 25,2024

Study fingers new player in cancer immunity

by Harvard Medical SchoolKiller T cells surround a cancer cell. Credit: NIHThe immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time res

Updated on:May 25,2024

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on: September 27,2024

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on:September 27,2024

Optimizing tobacco cessation treatment with lung cancer screening

byUniversity of MinnesotaVisual Abstract.Optimizing Longitudinal Tobacco Cessation Treatment in Lung Cancer Screening. Credit:JAMA Network Open(2023). DOI: 10.1001/jamanetworko

Updated on: January 07,2024

Optimizing tobacco cessation treatment with lung cancer screening

byUniversity of MinnesotaVisual Abstract.Optimizing Longitudinal Tobacco Cessation Treatment in Lung Cancer Screening. Credit:JAMA Network Open(2023). DOI: 10.1001/jamanetworko

Updated on:January 07,2024

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on: January 23,2024

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on:January 23,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on: January 23,2024

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on:January 23,2024

Researchers to develop handheld device to diagnose skin cancer

by Stevens Institute of TechnologyStevens researchers develop a technique based on reflectivity patterns that can distinguish multiple forms of skin cancer, including basal cell carcinoma (left)

Updated on: June 15,2024

Researchers to develop handheld device to diagnose skin cancer

by Stevens Institute of TechnologyStevens researchers develop a technique based on reflectivity patterns that can distinguish multiple forms of skin cancer, including basal cell carcinoma (left)

Updated on:June 15,2024

New heated drug baths provide hope for patients with stomach cancer

by Megan Lakatos,Mayo ClinicCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have used a new approach to chemotherapy to more than double the typical survival rate for patients with stom

Updated on: April 28,2024

New heated drug baths provide hope for patients with stomach cancer

by Megan Lakatos,Mayo ClinicCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have used a new approach to chemotherapy to more than double the typical survival rate for patients with stom

Updated on:April 28,2024

Specific components of the tumor immune microenvironment may affect responses to BCMA CAR T-cell therapy

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainPatients with myeloma whose tumor immune microenvironments had a more diverse baseline T-cell repertoire, fewer marker

Updated on: January 22,2024

Specific components of the tumor immune microenvironment may affect responses to BCMA CAR T-cell therapy

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainPatients with myeloma whose tumor immune microenvironments had a more diverse baseline T-cell repertoire, fewer marker

Updated on:January 22,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on: February 23,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on:February 23,2024