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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Advanced ovarian cancer drug gets initial 'no' for NHS in England

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r
70-gene signature impacts treatment decisions in breast CA

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud
No substantial benefit from transplantation reported for a high-risk leukemia subtype

No substantial benefit from transplantation reported for a high-risk leukemia subtype

by St. Jude Children's Research HospitalA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA

No substantial benefit from transplantation reported for a high-risk leukemia subtype

by St. Jude Children's Research HospitalA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA
Researchers show how a tumor cell's location and environment affect its identity

Researchers show how a tumor cell's location and environment affect its identity

by National Institutes of HealthDifferences in cell layers' fluorescent-dye uptake in a model of high-grade serous ovarian cancer. Credit: David B. Morse.Using 3D models of ovarian cancer tum

Researchers show how a tumor cell's location and environment affect its identity

by National Institutes of HealthDifferences in cell layers' fluorescent-dye uptake in a model of high-grade serous ovarian cancer. Credit: David B. Morse.Using 3D models of ovarian cancer tum
Researchers discover crucial step in creating blood stem cells

Researchers discover crucial step in creating blood stem cells

by Iowa State UniversityBlood stem cells show forming in the trunk of a zebrafish embryo. The blood stem cells are yellow, with the red tubes are the aorta on the top and a vein on the bottom. Cr

Researchers discover crucial step in creating blood stem cells

by Iowa State UniversityBlood stem cells show forming in the trunk of a zebrafish embryo. The blood stem cells are yellow, with the red tubes are the aorta on the top and a vein on the bottom. Cr
New biomarker for early prediction of response to CAR-T cell therapy

New biomarker for early prediction of response to CAR-T cell therapy

by Medical University of ViennaCredit: AI-generated imageA MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequ

New biomarker for early prediction of response to CAR-T cell therapy

by Medical University of ViennaCredit: AI-generated imageA MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequ
Team discovers broken 'brake' of cancer mutation machine

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that
Researchers suggest rethinking 'cancer' label for early-stage prostate changes

Researchers suggest rethinking 'cancer' label for early-stage prostate changes

byOxford University PressCredit: CC0 Public DomainA new paper in theJournal of the National Cancer Instituteindicates that patients may benefit if doctors stop calling certain early-

Researchers suggest rethinking 'cancer' label for early-stage prostate changes

byOxford University PressCredit: CC0 Public DomainA new paper in theJournal of the National Cancer Instituteindicates that patients may benefit if doctors stop calling certain early-
Cancer genes' age and function strongly influence their mutational status

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat
Research uncovers alternate mechanism for producing key protein in metastatic prostate cancer

Research uncovers alternate mechanism for producing key protein in metastatic prostate cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainLike the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physi

Research uncovers alternate mechanism for producing key protein in metastatic prostate cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainLike the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physi
Researchers identify new gene mutation in familial thyroid cancers

Researchers identify new gene mutation in familial thyroid cancers

by Pennsylvania State UniversityCredit: CC0 Public DomainResearchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid cancer. Dr. Darri

Researchers identify new gene mutation in familial thyroid cancers

by Pennsylvania State UniversityCredit: CC0 Public DomainResearchers from Penn State College of Medicine identified a new gene mutation that may cause a type of familial thyroid cancer. Dr. Darri
The protein behind immunotherapy resistance

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im