Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on: February 03,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on:February 03,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on: January 02,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on:January 02,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on: January 29,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on:January 29,2024

Researchers identify one driver of melanoma spread

by Amy Mone,Johns Hopkins UniversityCredit: AI-generated imageUsing a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in

Updated on: June 22,2024

Researchers identify one driver of melanoma spread

by Amy Mone,Johns Hopkins UniversityCredit: AI-generated imageUsing a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in

Updated on:June 22,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on: June 22,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on:June 22,2024

Researchers develop a study model for Ewing sarcoma in the Drosophila fly

by Institute for Research in Biomedicine (IRB Barcelona)EWS-FLI1FSinduces epithelial malignant tumors in the developing wing discs. Wing imaginal disc from a wild-type third instar larvae (

Updated on: February 20,2024

Researchers develop a study model for Ewing sarcoma in the Drosophila fly

by Institute for Research in Biomedicine (IRB Barcelona)EWS-FLI1FSinduces epithelial malignant tumors in the developing wing discs. Wing imaginal disc from a wild-type third instar larvae (

Updated on:February 20,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on: January 11,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on:January 11,2024

Colorectal cancer 'not an old people's disease anymore'

by University of Washington School of MedicineCredit: CC0 Public DomainThere are two statistics that Dr. Rachel Issaka would like people to seriously consider:In the last 30 years, the incidence

Updated on: March 20,2024

Colorectal cancer 'not an old people's disease anymore'

by University of Washington School of MedicineCredit: CC0 Public DomainThere are two statistics that Dr. Rachel Issaka would like people to seriously consider:In the last 30 years, the incidence

Updated on:March 20,2024

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on: March 06,2024

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on:March 06,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on: January 02,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on:January 02,2024

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on: May 13,2024

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on:May 13,2024

New immunotherapy targeting tumor macrophages to tackle lung cancer

by Germans Trias i Pujol Research InstituteRImAb modifies the intratumoral myeloid cell compartment in a mouse model of LLC. a) Myeloid cell gating classification using the expression of surface marke

Updated on: February 18,2024

New immunotherapy targeting tumor macrophages to tackle lung cancer

by Germans Trias i Pujol Research InstituteRImAb modifies the intratumoral myeloid cell compartment in a mouse model of LLC. a) Myeloid cell gating classification using the expression of surface marke

Updated on:February 18,2024