The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on: January 02,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on:January 02,2024

Chemotherapy in the afternoon dramatically improves treatment outcomes in female lymphoma patients: Study

by Institute for Basic ScienceThe daily fluctuation of proliferative activity of bone marrow is larger in females than in males, and it becomes higher in the morning (left). Thus, chemotherapy in

Updated on: February 01,2024

Chemotherapy in the afternoon dramatically improves treatment outcomes in female lymphoma patients: Study

by Institute for Basic ScienceThe daily fluctuation of proliferative activity of bone marrow is larger in females than in males, and it becomes higher in the morning (left). Thus, chemotherapy in

Updated on:February 01,2024

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris

Updated on: February 01,2024

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris

Updated on:February 01,2024

Research uncovers alternate mechanism for producing key protein in metastatic prostate cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainLike the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physi

Updated on: February 18,2024

Research uncovers alternate mechanism for producing key protein in metastatic prostate cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainLike the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physi

Updated on:February 18,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on: January 29,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on:January 29,2024

New reports examine COVID's radiotherapy interruption implications

by University of Tennessee Health Science Center(A-D) Major radiation therapy (RT) interruption rates before and during the pandemic mapped by ZIP code across the metropolitan region by race and insur

Updated on: January 11,2024

New reports examine COVID's radiotherapy interruption implications

by University of Tennessee Health Science Center(A-D) Major radiation therapy (RT) interruption rates before and during the pandemic mapped by ZIP code across the metropolitan region by race and insur

Updated on:January 11,2024

Cell competition may explain cancer relapses, research suggests

byUT Southwestern Medical CenterCredit:Cancer Discovery(2022). DOI: 10.1158/2159-8290.CD-22-0236A normal process called cell competition, in which healthy tissues eliminate unhealthy

Updated on: January 16,2024

Cell competition may explain cancer relapses, research suggests

byUT Southwestern Medical CenterCredit:Cancer Discovery(2022). DOI: 10.1158/2159-8290.CD-22-0236A normal process called cell competition, in which healthy tissues eliminate unhealthy

Updated on:January 16,2024

Testing method could point thousands more cancer patients to lifesaving treatment

byUniversity of OklahomaDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHNot all cancer therapies are successful, but cancer researchers increa

Updated on: March 27,2024

Testing method could point thousands more cancer patients to lifesaving treatment

byUniversity of OklahomaDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHNot all cancer therapies are successful, but cancer researchers increa

Updated on:March 27,2024

Researchers identify targeted therapy that can help children with deadly nerve cancer

by The Mount Sinai HospitalCredit: CC0 Public DomainMount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who wou

Updated on: June 08,2024

Researchers identify targeted therapy that can help children with deadly nerve cancer

by The Mount Sinai HospitalCredit: CC0 Public DomainMount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who wou

Updated on:June 08,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on: January 11,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on:January 11,2024

Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on: April 07,2024

Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on:April 07,2024

Study: Mitochondria engage the integrated stress response to promote tumor growth

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper, titled "Mitochondria engage the integrated stress response to promote tumor growth," was published inOncot

Updated on: January 30,2024

Study: Mitochondria engage the integrated stress response to promote tumor growth

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper, titled "Mitochondria engage the integrated stress response to promote tumor growth," was published inOncot

Updated on:January 30,2024