Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on: November 10,2024

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on:November 10,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on: February 03,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on:February 03,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on: January 29,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on:January 29,2024

New tools to manage rare eye cancer

by University College DublinTumor secretion of IL-6, IL-13, VEGF-A, and PlGF correlate with clinical characteristics in ex vivo, control-treated, primary UM patient tumors. (A) Schematic of the e

Updated on: January 29,2024

New tools to manage rare eye cancer

by University College DublinTumor secretion of IL-6, IL-13, VEGF-A, and PlGF correlate with clinical characteristics in ex vivo, control-treated, primary UM patient tumors. (A) Schematic of the e

Updated on:January 29,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on: June 22,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on:June 22,2024

Gray hair and wrinkles at an early age lead researchers to potential new treatment for rare cancer

by University of CopenhagenSchematic representation of the PandaOmics application for a rapid biomarker discovery and target characterization in cancer. Gene expression signatures have been exami

Updated on: February 18,2024

Gray hair and wrinkles at an early age lead researchers to potential new treatment for rare cancer

by University of CopenhagenSchematic representation of the PandaOmics application for a rapid biomarker discovery and target characterization in cancer. Gene expression signatures have been exami

Updated on:February 18,2024

Study: Mitochondria engage the integrated stress response to promote tumor growth

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper, titled "Mitochondria engage the integrated stress response to promote tumor growth," was published inOncot

Updated on: January 30,2024

Study: Mitochondria engage the integrated stress response to promote tumor growth

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper, titled "Mitochondria engage the integrated stress response to promote tumor growth," was published inOncot

Updated on:January 30,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on: January 02,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on:January 02,2024

New marker could detect fatal breast cancer up to one year earlier than current methods

by BioMed CentralMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainA new marker that could be used to diagnose fatal breast cancer up to one year ah

Updated on: March 01,2024

New marker could detect fatal breast cancer up to one year earlier than current methods

by BioMed CentralMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainA new marker that could be used to diagnose fatal breast cancer up to one year ah

Updated on:March 01,2024

Discovery of pancreatic neuroendocrine subtypes could help predict likelihood of recurrence

by Dana-Farber Cancer InstituteCredit: CC0 Public DomainResearchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors—known as pNETs—that have dramatically different risks

Updated on: May 13,2024

Discovery of pancreatic neuroendocrine subtypes could help predict likelihood of recurrence

by Dana-Farber Cancer InstituteCredit: CC0 Public DomainResearchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors—known as pNETs—that have dramatically different risks

Updated on:May 13,2024

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on: January 02,2024

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on:January 02,2024

Chemotherapy in the afternoon dramatically improves treatment outcomes in female lymphoma patients: Study

by Institute for Basic ScienceThe daily fluctuation of proliferative activity of bone marrow is larger in females than in males, and it becomes higher in the morning (left). Thus, chemotherapy in

Updated on: February 01,2024

Chemotherapy in the afternoon dramatically improves treatment outcomes in female lymphoma patients: Study

by Institute for Basic ScienceThe daily fluctuation of proliferative activity of bone marrow is larger in females than in males, and it becomes higher in the morning (left). Thus, chemotherapy in

Updated on:February 01,2024