Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies

byStanford University Medical CenterA machine-learning framework for large-scale identification and validation of sarcoma cell states and ecosystems. Credit:Nature Cancer(2024). DOI:

Updated on: March 30,2024

Novel AI tools tackle soft tissue sarcomas, identify new treatment strategies

byStanford University Medical CenterA machine-learning framework for large-scale identification and validation of sarcoma cell states and ecosystems. Credit:Nature Cancer(2024). DOI:

Updated on:March 30,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on: April 22,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on:April 22,2024

New method to determine before surgery which prostate tumors pose a lethal threat

by Cold Spring Harbor LaboratoryScreen shot from a new genome-viewing program (single cell genomic viewer, or SCGV) that displays results of CSHL's innovative method for analyzing diagnostic

Updated on: April 22,2024

New method to determine before surgery which prostate tumors pose a lethal threat

by Cold Spring Harbor LaboratoryScreen shot from a new genome-viewing program (single cell genomic viewer, or SCGV) that displays results of CSHL's innovative method for analyzing diagnostic

Updated on:April 22,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on: February 18,2024

Carcinogens found at Montana nuclear missile sites as reports of hundreds of cancers surface

by Tara CoppIn this image provided by the U.S. Air Force, Airman 1st Class Jackson Ligon, left, and Senior Airman Jonathan Marinaccio, 341st Missile Maintenance Squadron technicians connect a re-entry

Updated on:February 18,2024

Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

by Adam Pope,University of Alabama at BirminghamProtein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. Th

Updated on: February 18,2024

Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

by Adam Pope,University of Alabama at BirminghamProtein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. Th

Updated on:February 18,2024

Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on: May 25,2024

Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on:May 25,2024

New multimodal signature could predict immunotherapy success

byUniversity of InnsbruckCredit:iScience(2024). DOI: 10.1016/j.isci.2024.110529An international team of researchers led by Francesca Finotello from the Digital Science Center (DiSC)

Updated on: September 27,2024

New multimodal signature could predict immunotherapy success

byUniversity of InnsbruckCredit:iScience(2024). DOI: 10.1016/j.isci.2024.110529An international team of researchers led by Francesca Finotello from the Digital Science Center (DiSC)

Updated on:September 27,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on: November 09,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on:November 09,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on: May 21,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on:May 21,2024

Salmonella exposure a risk for colon cancer, finds study

byUniversity of Illinois at ChicagoGraphical Abstract. Credit:Cell Reports Medicine(2022). DOI: 10.1016/j.xcrm.2022.100852A new study published in the journalCell Reports Medic

Updated on: January 23,2024

Salmonella exposure a risk for colon cancer, finds study

byUniversity of Illinois at ChicagoGraphical Abstract. Credit:Cell Reports Medicine(2022). DOI: 10.1016/j.xcrm.2022.100852A new study published in the journalCell Reports Medic

Updated on:January 23,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on: February 03,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on:February 03,2024

Researchers demonstrate in mice a new way to deliver medication to malignant brain tumors

by Brown UniversityCredit:Journal of Controlled Release(2022). DOI: 10.1016/j.jconrel.2022.10.051Researchers have demonstrated in mice a new approach for delivering medication across

Updated on: February 18,2024

Researchers demonstrate in mice a new way to deliver medication to malignant brain tumors

by Brown UniversityCredit:Journal of Controlled Release(2022). DOI: 10.1016/j.jconrel.2022.10.051Researchers have demonstrated in mice a new approach for delivering medication across

Updated on:February 18,2024