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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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The protein behind immunotherapy resistance

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im

The protein behind immunotherapy resistance

byEcole Polytechnique Federale de LausanneTumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL).Im
Advanced ovarian cancer drug gets initial 'no' for NHS in England

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r
70-gene signature impacts treatment decisions in breast CA

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud
The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl
Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti
Prostate tumor biology may be influenced by genetic ancestry

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to
COVID-19 pandemic has left an enduring imprint on colorectal cancer surgery

COVID-19 pandemic has left an enduring imprint on colorectal cancer surgery

byAmerican College of SurgeonsCredit: CC0 Public DomainWhile the COVID-19 pandemic is no longer considered a public health emergency, pandemic-related stressors continue to impact cancer care ac

COVID-19 pandemic has left an enduring imprint on colorectal cancer surgery

byAmerican College of SurgeonsCredit: CC0 Public DomainWhile the COVID-19 pandemic is no longer considered a public health emergency, pandemic-related stressors continue to impact cancer care ac
Chemotherapy in the afternoon dramatically improves treatment outcomes in female lymphoma patients: Study

Chemotherapy in the afternoon dramatically improves treatment outcomes in female lymphoma patients: Study

by Institute for Basic ScienceThe daily fluctuation of proliferative activity of bone marrow is larger in females than in males, and it becomes higher in the morning (left). Thus, chemotherapy in

Chemotherapy in the afternoon dramatically improves treatment outcomes in female lymphoma patients: Study

by Institute for Basic ScienceThe daily fluctuation of proliferative activity of bone marrow is larger in females than in males, and it becomes higher in the morning (left). Thus, chemotherapy in
More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a
Cancer genes' age and function strongly influence their mutational status

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat
Researchers discover protective 'acid wall' formed by cancer cells

Researchers discover protective 'acid wall' formed by cancer cells

by UTSouthwestern Medical CenterCancer cells secrete acid with a significantly lower pH than previously known by researchers, a team from UTSW shows in a new study. Credit:Nature Biom

Researchers discover protective 'acid wall' formed by cancer cells

by UTSouthwestern Medical CenterCancer cells secrete acid with a significantly lower pH than previously known by researchers, a team from UTSW shows in a new study. Credit:Nature Biom
Researchers publish consensus statement on patient selection and appropriate use of Lu-177 PSMA-617 radionuclide therapy

Researchers publish consensus statement on patient selection and appropriate use of Lu-177 PSMA-617 radionuclide therapy

by Society of Nuclear Medicine and Molecular ImagingProstate cancer cells. Credit: NIH Image GalleryThe Society of Nuclear Medicine and Molecular Imaging (SNMMI) has issued a new consensus statement t

Researchers publish consensus statement on patient selection and appropriate use of Lu-177 PSMA-617 radionuclide therapy

by Society of Nuclear Medicine and Molecular ImagingProstate cancer cells. Credit: NIH Image GalleryThe Society of Nuclear Medicine and Molecular Imaging (SNMMI) has issued a new consensus statement t