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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Cancer genes' age and function strongly influence their mutational status

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat
Predicting cancer versus autism risk in PTEN patients

Predicting cancer versus autism risk in PTEN patients

by Cleveland ClinicIn a newly published study, a team of researchers led by Charis Eng, M.D., Ph.D., Chair of Cleveland Clinic's Genomic Medicine Institute, identified a metabolite that may p

Predicting cancer versus autism risk in PTEN patients

by Cleveland ClinicIn a newly published study, a team of researchers led by Charis Eng, M.D., Ph.D., Chair of Cleveland Clinic's Genomic Medicine Institute, identified a metabolite that may p
Researchers publish consensus statement on patient selection and appropriate use of Lu-177 PSMA-617 radionuclide therapy

Researchers publish consensus statement on patient selection and appropriate use of Lu-177 PSMA-617 radionuclide therapy

by Society of Nuclear Medicine and Molecular ImagingProstate cancer cells. Credit: NIH Image GalleryThe Society of Nuclear Medicine and Molecular Imaging (SNMMI) has issued a new consensus statement t

Researchers publish consensus statement on patient selection and appropriate use of Lu-177 PSMA-617 radionuclide therapy

by Society of Nuclear Medicine and Molecular ImagingProstate cancer cells. Credit: NIH Image GalleryThe Society of Nuclear Medicine and Molecular Imaging (SNMMI) has issued a new consensus statement t
Researchers identify one driver of melanoma spread

Researchers identify one driver of melanoma spread

by Amy Mone,Johns Hopkins UniversityCredit: AI-generated imageUsing a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in

Researchers identify one driver of melanoma spread

by Amy Mone,Johns Hopkins UniversityCredit: AI-generated imageUsing a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in
Testing method could point thousands more cancer patients to lifesaving treatment

Testing method could point thousands more cancer patients to lifesaving treatment

byUniversity of OklahomaDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHNot all cancer therapies are successful, but cancer researchers increa

Testing method could point thousands more cancer patients to lifesaving treatment

byUniversity of OklahomaDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHNot all cancer therapies are successful, but cancer researchers increa
Study suggests chromosomal errors may hinder some aggressive tumors

Study suggests chromosomal errors may hinder some aggressive tumors

by Julie Vera,Mayo ClinicGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.100937Chromosomal errors are a hallmark of cancer cells. Defects in the geno

Study suggests chromosomal errors may hinder some aggressive tumors

by Julie Vera,Mayo ClinicGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.100937Chromosomal errors are a hallmark of cancer cells. Defects in the geno
Bone cells suppress cancer metastases

Bone cells suppress cancer metastases

by Thomas Jefferson UniversityCredit: CC0 Public DomainIn breast cancer, there are cases of women and men whose cancer returns in their bones 20-30 years after they were treated for their primary

Bone cells suppress cancer metastases

by Thomas Jefferson UniversityCredit: CC0 Public DomainIn breast cancer, there are cases of women and men whose cancer returns in their bones 20-30 years after they were treated for their primary
70-gene signature impacts treatment decisions in breast CA

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud
11 percent of cancers detected via emergency visit

11 percent of cancers detected via emergency visit

About 11 percent of cancers are diagnosed following an emergency department visit, according to a study presented at the 12th AACR Conference on The Science of Cancer Health Disparities in Racial/Ethn

11 percent of cancers detected via emergency visit

About 11 percent of cancers are diagnosed following an emergency department visit, according to a study presented at the 12th AACR Conference on The Science of Cancer Health Disparities in Racial/Ethn
Researchers show how a tumor cell's location and environment affect its identity

Researchers show how a tumor cell's location and environment affect its identity

by National Institutes of HealthDifferences in cell layers' fluorescent-dye uptake in a model of high-grade serous ovarian cancer. Credit: David B. Morse.Using 3D models of ovarian cancer tum

Researchers show how a tumor cell's location and environment affect its identity

by National Institutes of HealthDifferences in cell layers' fluorescent-dye uptake in a model of high-grade serous ovarian cancer. Credit: David B. Morse.Using 3D models of ovarian cancer tum
Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti

Investigating the immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

by Impact Journals LLCMultiple mechanisms underly the pro-tumorigenic role of CD200. Credit: 2023 Shao and Owens.A new research perspective titled "The immunoregulatory protein CD200 as a potenti
Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

by Salk InstituteCredit: Human Brain ProjectGlioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous

Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

by Salk InstituteCredit: Human Brain ProjectGlioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous