Certain gene signaling rewires tumors after immunotherapy

by Anna Megdell,University of MichiganGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2022.12.008Researchers from the University of Michigan Rogel Cancer Center ha

Updated on: January 02,2024

Certain gene signaling rewires tumors after immunotherapy

by Anna Megdell,University of MichiganGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2022.12.008Researchers from the University of Michigan Rogel Cancer Center ha

Updated on:January 02,2024

Technique that characterizes different immune cell groups in individual patients could revolutionize cancer treatments

by Agency for Science, Technology and Research (A*STAR), SingaporeA plot of all the different possible phenotypes of T cells before without (left) vs. with (right) immune checkpoint blockade immu

Updated on: March 01,2024

Technique that characterizes different immune cell groups in individual patients could revolutionize cancer treatments

by Agency for Science, Technology and Research (A*STAR), SingaporeA plot of all the different possible phenotypes of T cells before without (left) vs. with (right) immune checkpoint blockade immu

Updated on:March 01,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on: January 02,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on:January 02,2024

New promising targeted drug for a rare leukemia

by University of HelsinkiBCL-2 family gene expression in blasts across AML types at single cell resolution. (A) UMAP plot of scRNA-seq data of blasts from AML with megakaryoblastic differentiatio

Updated on: February 18,2024

New promising targeted drug for a rare leukemia

by University of HelsinkiBCL-2 family gene expression in blasts across AML types at single cell resolution. (A) UMAP plot of scRNA-seq data of blasts from AML with megakaryoblastic differentiatio

Updated on:February 18,2024

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris

Updated on: February 01,2024

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris

Updated on:February 01,2024

Research uncovers alternate mechanism for producing key protein in metastatic prostate cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainLike the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physi

Updated on: February 18,2024

Research uncovers alternate mechanism for producing key protein in metastatic prostate cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainLike the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physi

Updated on:February 18,2024

Unhealthy gut sets stage for breast cancer to spread, research reveals

byUniversity of VirginiaCredit: Unsplash/CC0 Public DomainAn unhealthy gut triggers changes in normal breast tissue that helps breast cancer spread to other parts of the body, new research from

Updated on: January 16,2024

Unhealthy gut sets stage for breast cancer to spread, research reveals

byUniversity of VirginiaCredit: Unsplash/CC0 Public DomainAn unhealthy gut triggers changes in normal breast tissue that helps breast cancer spread to other parts of the body, new research from

Updated on:January 16,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on: January 29,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on:January 29,2024

New reports examine COVID's radiotherapy interruption implications

by University of Tennessee Health Science Center(A-D) Major radiation therapy (RT) interruption rates before and during the pandemic mapped by ZIP code across the metropolitan region by race and insur

Updated on: January 11,2024

New reports examine COVID's radiotherapy interruption implications

by University of Tennessee Health Science Center(A-D) Major radiation therapy (RT) interruption rates before and during the pandemic mapped by ZIP code across the metropolitan region by race and insur

Updated on:January 11,2024

Cell competition may explain cancer relapses, research suggests

byUT Southwestern Medical CenterCredit:Cancer Discovery(2022). DOI: 10.1158/2159-8290.CD-22-0236A normal process called cell competition, in which healthy tissues eliminate unhealthy

Updated on: January 16,2024

Cell competition may explain cancer relapses, research suggests

byUT Southwestern Medical CenterCredit:Cancer Discovery(2022). DOI: 10.1158/2159-8290.CD-22-0236A normal process called cell competition, in which healthy tissues eliminate unhealthy

Updated on:January 16,2024

Testing method could point thousands more cancer patients to lifesaving treatment

byUniversity of OklahomaDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHNot all cancer therapies are successful, but cancer researchers increa

Updated on: March 27,2024

Testing method could point thousands more cancer patients to lifesaving treatment

byUniversity of OklahomaDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHNot all cancer therapies are successful, but cancer researchers increa

Updated on:March 27,2024

Researchers identify targeted therapy that can help children with deadly nerve cancer

by The Mount Sinai HospitalCredit: CC0 Public DomainMount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who wou

Updated on: June 08,2024

Researchers identify targeted therapy that can help children with deadly nerve cancer

by The Mount Sinai HospitalCredit: CC0 Public DomainMount Sinai researchers have identified a targeted therapy for adolescent patients with neuroblastoma, a deadly pediatric nerve cancer, who wou

Updated on:June 08,2024