Virus-targeting white blood cells in tumors offer intriguing insights into responsiveness to immunotherapy

by Agency for Science, Technology and Research (A*STAR), SingaporeGreen and red tumor-infiltrating lymphocytes expressing CD39 in human lung cancer. Credit: A*STAR Singapore Immunology NetworkBys

Updated on: March 06,2024

Virus-targeting white blood cells in tumors offer intriguing insights into responsiveness to immunotherapy

by Agency for Science, Technology and Research (A*STAR), SingaporeGreen and red tumor-infiltrating lymphocytes expressing CD39 in human lung cancer. Credit: A*STAR Singapore Immunology NetworkBys

Updated on:March 06,2024

Old chemo drug, new pancreatic cancer therapy?

Updated on: September 10,2024

Old chemo drug, new pancreatic cancer therapy?

Updated on:September 10,2024

Researchers use AI to personalize cancer patient treatments

by University of SussexCredit: CC0 Public DomainResearchers at the University of Sussex are using Artificial Intelligence (AI) technology to analyze different types of cancer cells to understand

Updated on: February 01,2024

Researchers use AI to personalize cancer patient treatments

by University of SussexCredit: CC0 Public DomainResearchers at the University of Sussex are using Artificial Intelligence (AI) technology to analyze different types of cancer cells to understand

Updated on:February 01,2024

Target discovered for the treatment of pancreatic cancer

byKiel UniversityAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA team at the Institute of Biochemistry at Kiel University has found a

Updated on: July 05,2024

Target discovered for the treatment of pancreatic cancer

byKiel UniversityAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA team at the Institute of Biochemistry at Kiel University has found a

Updated on:July 05,2024

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on: February 03,2024

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on:February 03,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on: April 23,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on:April 23,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on: January 02,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on:January 02,2024

Mutation analysis on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new research paper was published inOncotargetentitled, "Mutation analysis performed on tumor biopsies from patients with newly

Updated on: January 15,2024

Mutation analysis on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new research paper was published inOncotargetentitled, "Mutation analysis performed on tumor biopsies from patients with newly

Updated on:January 15,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on: August 03,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on:August 03,2024

Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (

Updated on: January 02,2024

Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (

Updated on:January 02,2024

Metachronous pathology assessed in young-onset colorectal cancer survivors

The incidence rate of clinically significant metachronous colorectal pathology is 32 per 1,000 person-years after index young-onset colorectal cancer (YOCRC), according to a research letter published

Updated on: January 02,2024

Metachronous pathology assessed in young-onset colorectal cancer survivors

The incidence rate of clinically significant metachronous colorectal pathology is 32 per 1,000 person-years after index young-onset colorectal cancer (YOCRC), according to a research letter published

Updated on:January 02,2024

Healthy gut bacteria can help fight cancer in other parts of the body, researchers find

by UT Southwestern Medical CenterImmune checkpoint therapy (ICT) helps gut microbiota travel from the gut to the lymph nodes where they activate immune cells (dendritic cells and T cells). Ultima

Updated on: February 01,2024

Healthy gut bacteria can help fight cancer in other parts of the body, researchers find

by UT Southwestern Medical CenterImmune checkpoint therapy (ICT) helps gut microbiota travel from the gut to the lymph nodes where they activate immune cells (dendritic cells and T cells). Ultima

Updated on:February 01,2024