An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on: April 14,2024

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on:April 14,2024

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Updated on: January 02,2024

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Updated on:January 02,2024

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on: April 30,2024

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on:April 30,2024

'Exhausted' immune cells in healthy women could be target for breast cancer prevention

byUniversity of CambridgeImmune cell exhaustion is observed in breast tissue from carriers of BRCA1 and BRCA2 mutations long before breast cancer develops. Credit: Sara Pensa/University of Cambr

Updated on: March 30,2024

'Exhausted' immune cells in healthy women could be target for breast cancer prevention

byUniversity of CambridgeImmune cell exhaustion is observed in breast tissue from carriers of BRCA1 and BRCA2 mutations long before breast cancer develops. Credit: Sara Pensa/University of Cambr

Updated on:March 30,2024

Drug approved to help young patients battle a rare cancer

by Cara Murez HealthDay ReporterChildren and adults with a rare type of soft tissue cancer will now have a new treatment option that could have a big impact.The U.S. Food and Drug Administration has&n

Updated on: February 01,2024

Drug approved to help young patients battle a rare cancer

by Cara Murez HealthDay ReporterChildren and adults with a rare type of soft tissue cancer will now have a new treatment option that could have a big impact.The U.S. Food and Drug Administration has&n

Updated on:February 01,2024

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a

Updated on: January 23,2024

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a

Updated on:January 23,2024

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on: April 09,2024

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on:April 09,2024

Delaying antibiotics for neutropenic fever may not affect survival of cancer inpatients

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainIn cancer patients with neutropenic fever, delaying antibiotic treatment past 60 minutes from the time of fever detection does not reduce

Updated on: January 16,2024

Delaying antibiotics for neutropenic fever may not affect survival of cancer inpatients

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainIn cancer patients with neutropenic fever, delaying antibiotic treatment past 60 minutes from the time of fever detection does not reduce

Updated on:January 16,2024

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet

Updated on: January 22,2024

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet

Updated on:January 22,2024

Mutation analysis on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new research paper was published inOncotargetentitled, "Mutation analysis performed on tumor biopsies from patients with newly

Updated on: January 15,2024

Mutation analysis on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new research paper was published inOncotargetentitled, "Mutation analysis performed on tumor biopsies from patients with newly

Updated on:January 15,2024

Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on: April 07,2024

Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on:April 07,2024