Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on: January 02,2024 9

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on:January 02,2024 9

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on: January 02,2024 8

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on:January 02,2024 8

First randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

by ECOG-ACRIN Cancer Research GroupCredit: Pixabay/CC0 Public DomainThe ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present data from PROSPER RCC (EA8143), the first randomized phase 3 trial of

Updated on: January 04,2024 8

First randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

by ECOG-ACRIN Cancer Research GroupCredit: Pixabay/CC0 Public DomainThe ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present data from PROSPER RCC (EA8143), the first randomized phase 3 trial of

Updated on:January 04,2024 8

Researchers publish action plan to address appendiceal cancer enigmas

Updated on: April 29,2025 0

Researchers publish action plan to address appendiceal cancer enigmas

Updated on:April 29,2025 0

Researchers identify markers of chemotherapy resistance and outcome in triple negative breast cancer

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine and the Broad Institute of MIT and Harvard and clinicians at Washington Univer

Updated on: February 01,2024 10

Researchers identify markers of chemotherapy resistance and outcome in triple negative breast cancer

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine and the Broad Institute of MIT and Harvard and clinicians at Washington Univer

Updated on:February 01,2024 10

Stress granules may drive obesity-associated pancreatic cancer

byThomas Jefferson UniversityCredit: Pixabay/CC0 Public DomainObesity is a known risk factor for at least13 types of cancer, in part because it creates ever-present inflammatory state. For

Updated on: January 16,2024 20

Stress granules may drive obesity-associated pancreatic cancer

byThomas Jefferson UniversityCredit: Pixabay/CC0 Public DomainObesity is a known risk factor for at least13 types of cancer, in part because it creates ever-present inflammatory state. For

Updated on:January 16,2024 20

Unlocking the potential of bispecific antibody-drug conjugates for targeted cancer therapy

by Frontiers JournalsCredit: Unsplash/CC0 Public DomainAntibody-drug conjugates (ADCs) have emerged as a promising approach in cancer therapy, offering a 'magic bullet' strategy that combines

Updated on: November 09,2024 0

Unlocking the potential of bispecific antibody-drug conjugates for targeted cancer therapy

by Frontiers JournalsCredit: Unsplash/CC0 Public DomainAntibody-drug conjugates (ADCs) have emerged as a promising approach in cancer therapy, offering a 'magic bullet' strategy that combines

Updated on:November 09,2024 0

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on: May 21,2024 6

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on:May 21,2024 6

Breakdown of normal 3-D shape of DNA allows harmful interactions of genes in rare form of gastrointestinal stromal tumor

by Massachusetts General HospitalCredit: CC0 Public DomainMost cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be

Updated on: April 20,2024 17

Breakdown of normal 3-D shape of DNA allows harmful interactions of genes in rare form of gastrointestinal stromal tumor

by Massachusetts General HospitalCredit: CC0 Public DomainMost cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be

Updated on:April 20,2024 17

New gene implicated in cancer, cellular stress response

by Olivia Dimmer,Northwestern UniversityTissue-restricted expression of mammalian HAPSTR2. a Transcript abundance of HAPSTR1 and HAPSTR2 in the indicated human tissues; GTEx RNA-seq data. TPM, t

Updated on: February 18,2024 20

New gene implicated in cancer, cellular stress response

by Olivia Dimmer,Northwestern UniversityTissue-restricted expression of mammalian HAPSTR2. a Transcript abundance of HAPSTR1 and HAPSTR2 in the indicated human tissues; GTEx RNA-seq data. TPM, t

Updated on:February 18,2024 20

Biosensors for bladder cancer diagnosis

by University of BathCredit: AI-generated imageCancer constitutes one of the leading causes of mortality worldwide. As early diagnosis is paramount to improved clinical outcome and survival, sens

Updated on: May 09,2024 8

Biosensors for bladder cancer diagnosis

by University of BathCredit: AI-generated imageCancer constitutes one of the leading causes of mortality worldwide. As early diagnosis is paramount to improved clinical outcome and survival, sens

Updated on:May 09,2024 8

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on: January 22,2024 13

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on:January 22,2024 13