Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

by Adam Pope,University of Alabama at BirminghamProtein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. Th

Updated on: February 18,2024

Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

by Adam Pope,University of Alabama at BirminghamProtein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. Th

Updated on:February 18,2024

Target discovered for the treatment of pancreatic cancer

byKiel UniversityAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA team at the Institute of Biochemistry at Kiel University has found a

Updated on: July 05,2024

Target discovered for the treatment of pancreatic cancer

byKiel UniversityAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA team at the Institute of Biochemistry at Kiel University has found a

Updated on:July 05,2024

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on: February 18,2024

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on:February 18,2024

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on: February 03,2024

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on:February 03,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on: April 23,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on:April 23,2024

Mutation analysis on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new research paper was published inOncotargetentitled, "Mutation analysis performed on tumor biopsies from patients with newly

Updated on: January 15,2024

Mutation analysis on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new research paper was published inOncotargetentitled, "Mutation analysis performed on tumor biopsies from patients with newly

Updated on:January 15,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on: June 08,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on:June 08,2024

Adhering to global health recommendations reduces cancer risk

byNewcastle UniversityCredit: CC0 Public DomainPeople who adhere to global Cancer Prevention Recommendations are putting themselves at lower risk of developing the disease, new research confirms

Updated on: January 22,2024

Adhering to global health recommendations reduces cancer risk

byNewcastle UniversityCredit: CC0 Public DomainPeople who adhere to global Cancer Prevention Recommendations are putting themselves at lower risk of developing the disease, new research confirms

Updated on:January 22,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on: August 03,2024

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Updated on:August 03,2024

Experts call for a targeted approach to cancer prevention

by University of StirlingCredit: CC0 Public DomainPolicymakers around the world should consider introducing more targeted early interventions in a bid to tackle cancer, according to experts at th

Updated on: April 07,2024

Experts call for a targeted approach to cancer prevention

by University of StirlingCredit: CC0 Public DomainPolicymakers around the world should consider introducing more targeted early interventions in a bid to tackle cancer, according to experts at th

Updated on:April 07,2024

Study shows immunotherapy may benefit a subset of patients with penile cancer

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPenile cancer is a rare disease with approximately 2,070 new cases each year in the U.S. Treatment options are limited and typical

Updated on: January 22,2024

Study shows immunotherapy may benefit a subset of patients with penile cancer

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPenile cancer is a rare disease with approximately 2,070 new cases each year in the U.S. Treatment options are limited and typical

Updated on:January 22,2024

A new therapeutic target for metastatic and resistant prostate cancers

by IDIBELL-Bellvitge Biomedical Research InstituteÁlvaro Aytés & Katia Ruggero. Credit: IDIBELLProstate Cancer researchers from the Bellvitge Biomedical Research Institute (IDIBELL), led by D

Updated on: April 01,2024

A new therapeutic target for metastatic and resistant prostate cancers

by IDIBELL-Bellvitge Biomedical Research InstituteÁlvaro Aytés & Katia Ruggero. Credit: IDIBELLProstate Cancer researchers from the Bellvitge Biomedical Research Institute (IDIBELL), led by D

Updated on:April 01,2024