Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on: April 07,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on:April 07,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on: February 23,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on:February 23,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on: January 02,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on:January 02,2024

Researcher explores new treatment for advanced biliary tract cancers

by Blair Willis,University of ArizonaCredit: CC0 Public DomainA new treatment that may extend survival for patients with advanced biliary tract cancers—who typically face a grim outlook with ave

Updated on: June 06,2024

Researcher explores new treatment for advanced biliary tract cancers

by Blair Willis,University of ArizonaCredit: CC0 Public DomainA new treatment that may extend survival for patients with advanced biliary tract cancers—who typically face a grim outlook with ave

Updated on:June 06,2024

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on: March 30,2024

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on:March 30,2024

Study: Anti-PD-L1 antibody enhances curative effect of cryoablation

by Compuscript LtdGraphical abstract. Credit:Acta Pharmaceutica Sinica B(2022). DOI: 10.1016/j.apsb.2022.08.006A new article published inActa Pharmaceutica Sinica Bdiscusses ho

Updated on: January 30,2024

Study: Anti-PD-L1 antibody enhances curative effect of cryoablation

by Compuscript LtdGraphical abstract. Credit:Acta Pharmaceutica Sinica B(2022). DOI: 10.1016/j.apsb.2022.08.006A new article published inActa Pharmaceutica Sinica Bdiscusses ho

Updated on:January 30,2024

Researchers report on inhibitory effect of glioblastoma signals to macrophages

by University of BaselGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0"Don't eat me," is how one might translate the signal that the cancer cells in a glioblastoma sen

Updated on: February 18,2024

Researchers report on inhibitory effect of glioblastoma signals to macrophages

by University of BaselGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0"Don't eat me," is how one might translate the signal that the cancer cells in a glioblastoma sen

Updated on:February 18,2024

An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong

Updated on: January 30,2024

An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong

Updated on:January 30,2024

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on: January 22,2024

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on:January 22,2024

New precision therapy for bile duct cancer extends patients' lives

byUniversity College LondonCredit: Pixabay/CC0 Public DomainA new personalized cancer treatment can radically improve the outlook for some patients with bile duct cancer, finds an international

Updated on: January 12,2024

New precision therapy for bile duct cancer extends patients' lives

byUniversity College LondonCredit: Pixabay/CC0 Public DomainA new personalized cancer treatment can radically improve the outlook for some patients with bile duct cancer, finds an international

Updated on:January 12,2024

Boosting T cell 'memory' may result in longer-lasting and effective responses for patients

by University of Texas M. D. Anderson Cancer CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDJust like pe

Updated on: April 18,2024

Boosting T cell 'memory' may result in longer-lasting and effective responses for patients

by University of Texas M. D. Anderson Cancer CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDJust like pe

Updated on:April 18,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on: February 24,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on:February 24,2024