Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on: January 02,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on:January 02,2024

Study: Mitochondria engage the integrated stress response to promote tumor growth

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper, titled "Mitochondria engage the integrated stress response to promote tumor growth," was published inOncot

Updated on: January 30,2024

Study: Mitochondria engage the integrated stress response to promote tumor growth

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial paper, titled "Mitochondria engage the integrated stress response to promote tumor growth," was published inOncot

Updated on:January 30,2024

No substantial benefit from transplantation reported for a high-risk leukemia subtype

by St. Jude Children's Research HospitalA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA

Updated on: May 13,2024

No substantial benefit from transplantation reported for a high-risk leukemia subtype

by St. Jude Children's Research HospitalA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA

Updated on:May 13,2024

Five ways research can prevent cancer

by Sophia Lowes,Cancer Research UKCredit: Jill WatsonWe recently published landmark researchshowing how lifestyle can influence our risk of cancer, and what factors could help prevent it.

Updated on: March 01,2024

Five ways research can prevent cancer

by Sophia Lowes,Cancer Research UKCredit: Jill WatsonWe recently published landmark researchshowing how lifestyle can influence our risk of cancer, and what factors could help prevent it.

Updated on:March 01,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on: March 30,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on:March 30,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on: February 03,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on:February 03,2024

Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica

Updated on: February 18,2024

Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica

Updated on:February 18,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on: November 09,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on:November 09,2024

Newly developed gene classifier identifies risk of pre-breast cancer progression

byDuke University Medical CenterCohorts and methods outline. Two retrospective study cohorts were generated, consisting of ductal carcinoma in situ (DCIS) patients with either a subsequent ipsil

Updated on: January 13,2024

Newly developed gene classifier identifies risk of pre-breast cancer progression

byDuke University Medical CenterCohorts and methods outline. Two retrospective study cohorts were generated, consisting of ductal carcinoma in situ (DCIS) patients with either a subsequent ipsil

Updated on:January 13,2024

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on: January 22,2024

Reconsidering oxygen's role in growth of tumors

byYale UniversityGraphical abstract. Credit:Cell Systems(2022). DOI: 10.1016/j.cels.2022.11.003Yale researchers have made a discovery that changes conventional thinking about the rol

Updated on:January 22,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on: April 07,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on:April 07,2024

Erectile dysfunction drugs and flu vaccine may work together to help immune system fight cancer after surgery

by The Ottawa HospitalNew research shows that erectile dysfunction drugs and flu vaccine may work together to help the immune system fight cancer after surgery. Credit: The Ottawa HospitalA new study

Updated on: April 10,2024

Erectile dysfunction drugs and flu vaccine may work together to help immune system fight cancer after surgery

by The Ottawa HospitalNew research shows that erectile dysfunction drugs and flu vaccine may work together to help the immune system fight cancer after surgery. Credit: The Ottawa HospitalA new study

Updated on:April 10,2024