Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica

Updated on: February 18,2024

Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica

Updated on:February 18,2024

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on: September 27,2024

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on:September 27,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on: November 09,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on:November 09,2024

Optimizing tobacco cessation treatment with lung cancer screening

byUniversity of MinnesotaVisual Abstract.Optimizing Longitudinal Tobacco Cessation Treatment in Lung Cancer Screening. Credit:JAMA Network Open(2023). DOI: 10.1001/jamanetworko

Updated on: January 07,2024

Optimizing tobacco cessation treatment with lung cancer screening

byUniversity of MinnesotaVisual Abstract.Optimizing Longitudinal Tobacco Cessation Treatment in Lung Cancer Screening. Credit:JAMA Network Open(2023). DOI: 10.1001/jamanetworko

Updated on:January 07,2024

New imaging information system could speed up prognosis for certain cancers

byCU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainResearchers at the University of Colorado Anschutz Medical Campus have found that a new imaging information system may ultimately pro

Updated on: January 13,2024

New imaging information system could speed up prognosis for certain cancers

byCU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainResearchers at the University of Colorado Anschutz Medical Campus have found that a new imaging information system may ultimately pro

Updated on:January 13,2024

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Updated on: January 03,2024

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Updated on:January 03,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on: February 23,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on:February 23,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on: January 02,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on:January 02,2024

No substantial benefit from transplantation reported for a high-risk leukemia subtype

by St. Jude Children's Research HospitalA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA

Updated on: May 13,2024

No substantial benefit from transplantation reported for a high-risk leukemia subtype

by St. Jude Children's Research HospitalA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA

Updated on:May 13,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on: February 24,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on:February 24,2024

Study: Anti-PD-L1 antibody enhances curative effect of cryoablation

by Compuscript LtdGraphical abstract. Credit:Acta Pharmaceutica Sinica B(2022). DOI: 10.1016/j.apsb.2022.08.006A new article published inActa Pharmaceutica Sinica Bdiscusses ho

Updated on: January 30,2024

Study: Anti-PD-L1 antibody enhances curative effect of cryoablation

by Compuscript LtdGraphical abstract. Credit:Acta Pharmaceutica Sinica B(2022). DOI: 10.1016/j.apsb.2022.08.006A new article published inActa Pharmaceutica Sinica Bdiscusses ho

Updated on:January 30,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on: March 30,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on:March 30,2024