Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on: February 03,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on:February 03,2024

'Exhausted' immune cells in healthy women could be target for breast cancer prevention

byUniversity of CambridgeImmune cell exhaustion is observed in breast tissue from carriers of BRCA1 and BRCA2 mutations long before breast cancer develops. Credit: Sara Pensa/University of Cambr

Updated on: March 30,2024

'Exhausted' immune cells in healthy women could be target for breast cancer prevention

byUniversity of CambridgeImmune cell exhaustion is observed in breast tissue from carriers of BRCA1 and BRCA2 mutations long before breast cancer develops. Credit: Sara Pensa/University of Cambr

Updated on:March 30,2024

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on: February 18,2024

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Updated on:February 18,2024

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on: February 03,2024

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on:February 03,2024

New gene implicated in cancer, cellular stress response

by Olivia Dimmer,Northwestern UniversityTissue-restricted expression of mammalian HAPSTR2. a Transcript abundance of HAPSTR1 and HAPSTR2 in the indicated human tissues; GTEx RNA-seq data. TPM, t

Updated on: February 18,2024

New gene implicated in cancer, cellular stress response

by Olivia Dimmer,Northwestern UniversityTissue-restricted expression of mammalian HAPSTR2. a Transcript abundance of HAPSTR1 and HAPSTR2 in the indicated human tissues; GTEx RNA-seq data. TPM, t

Updated on:February 18,2024

Researchers develop novel photo-oxidation therapy for anticancer treatment

by City University of Hong KongThe CityU team developed a new class of near-infrared-activated platinum(IV) photo-oxidants that can effectively eliminate cancer cells in an oxygen-independent man

Updated on: June 08,2024

Researchers develop novel photo-oxidation therapy for anticancer treatment

by City University of Hong KongThe CityU team developed a new class of near-infrared-activated platinum(IV) photo-oxidants that can effectively eliminate cancer cells in an oxygen-independent man

Updated on:June 08,2024

Researchers exploit DNA amplification in cancer to halt chemoresistance

by Stony Brook UniversityGábor Balázsi, in his Biomedical Engineering laboratory with Rafal Krzysztoń, PhD, and Yiming Wan, PhD, both first co-authors on thePNASpaper. Credit: John Gr

Updated on: June 08,2024

Researchers exploit DNA amplification in cancer to halt chemoresistance

by Stony Brook UniversityGábor Balázsi, in his Biomedical Engineering laboratory with Rafal Krzysztoń, PhD, and Yiming Wan, PhD, both first co-authors on thePNASpaper. Credit: John Gr

Updated on:June 08,2024

Experts advise against routine testing for prostate cancer

by British Medical JournalMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Routine testing for prostate cancer is n

Updated on: April 07,2024

Experts advise against routine testing for prostate cancer

by British Medical JournalMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Routine testing for prostate cancer is n

Updated on:April 07,2024

Targeting a unique metabolic pathway might starve pancreatic cancer

by Nancy Fliesler and Andrea Tamayo,Broad Institute of MIT and HarvardMItochondrial staining (red) and nuclear staining (blue) of abnormal pancreatic ducts from a mouse model of human pancreatic

Updated on: February 18,2024

Targeting a unique metabolic pathway might starve pancreatic cancer

by Nancy Fliesler and Andrea Tamayo,Broad Institute of MIT and HarvardMItochondrial staining (red) and nuclear staining (blue) of abnormal pancreatic ducts from a mouse model of human pancreatic

Updated on:February 18,2024

App an effective tool to record sun exposure

by Queensland University of TechnologyCredit: Queensland University of TechnologyA smartphone app is an accessible tool that reliably measures the amount of exposure to the sun's skin-damagin

Updated on: March 30,2024

App an effective tool to record sun exposure

by Queensland University of TechnologyCredit: Queensland University of TechnologyA smartphone app is an accessible tool that reliably measures the amount of exposure to the sun's skin-damagin

Updated on:March 30,2024

Researchers accurately predict how well body will fight lung cancer based on patterns of immune cells

by Case Western Reserve UniversityActual photographs of the shape of the cancer-associated immune cells. Credit: Case Western Reserve UniversityResearchers at Case Western Reserve University have

Updated on: March 01,2024

Researchers accurately predict how well body will fight lung cancer based on patterns of immune cells

by Case Western Reserve UniversityActual photographs of the shape of the cancer-associated immune cells. Credit: Case Western Reserve UniversityResearchers at Case Western Reserve University have

Updated on:March 01,2024

Japan to trial 'world's first urine test' to spot cancer

Credit: CC0 Public DomainA Japanese firm is poised to carry out what it hailed as the world's first experiment to test for cancer using urine samples, which would greatly facilitate screening for

Updated on: March 01,2024

Japan to trial 'world's first urine test' to spot cancer

Credit: CC0 Public DomainA Japanese firm is poised to carry out what it hailed as the world's first experiment to test for cancer using urine samples, which would greatly facilitate screening for

Updated on:March 01,2024