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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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New tools to manage rare eye cancer

New tools to manage rare eye cancer

by University College DublinTumor secretion of IL-6, IL-13, VEGF-A, and PlGF correlate with clinical characteristics in ex vivo, control-treated, primary UM patient tumors. (A) Schematic of the e

New tools to manage rare eye cancer

by University College DublinTumor secretion of IL-6, IL-13, VEGF-A, and PlGF correlate with clinical characteristics in ex vivo, control-treated, primary UM patient tumors. (A) Schematic of the e
Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.
Researchers develop a study model for Ewing sarcoma in the Drosophila fly

Researchers develop a study model for Ewing sarcoma in the Drosophila fly

by Institute for Research in Biomedicine (IRB Barcelona)EWS-FLI1FSinduces epithelial malignant tumors in the developing wing discs. Wing imaginal disc from a wild-type third instar larvae (

Researchers develop a study model for Ewing sarcoma in the Drosophila fly

by Institute for Research in Biomedicine (IRB Barcelona)EWS-FLI1FSinduces epithelial malignant tumors in the developing wing discs. Wing imaginal disc from a wild-type third instar larvae (
Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper
Colorectal cancer 'not an old people's disease anymore'

Colorectal cancer 'not an old people's disease anymore'

by University of Washington School of MedicineCredit: CC0 Public DomainThere are two statistics that Dr. Rachel Issaka would like people to seriously consider:In the last 30 years, the incidence

Colorectal cancer 'not an old people's disease anymore'

by University of Washington School of MedicineCredit: CC0 Public DomainThere are two statistics that Dr. Rachel Issaka would like people to seriously consider:In the last 30 years, the incidence
Advanced ovarian cancer drug gets initial 'no' for NHS in England

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r
Merck, Moderna detail potential skin cancer vaccine progress

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p
Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre
New immunotherapy targeting tumor macrophages to tackle lung cancer

New immunotherapy targeting tumor macrophages to tackle lung cancer

by Germans Trias i Pujol Research InstituteRImAb modifies the intratumoral myeloid cell compartment in a mouse model of LLC. a) Myeloid cell gating classification using the expression of surface marke

New immunotherapy targeting tumor macrophages to tackle lung cancer

by Germans Trias i Pujol Research InstituteRImAb modifies the intratumoral myeloid cell compartment in a mouse model of LLC. a) Myeloid cell gating classification using the expression of surface marke
Researchers uncovers promising cancer target for liposarcoma

Researchers uncovers promising cancer target for liposarcoma

by National University of SingaporeCredit: CC0 Public DomainA study conducted by a team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of

Researchers uncovers promising cancer target for liposarcoma

by National University of SingaporeCredit: CC0 Public DomainA study conducted by a team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of
First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris
New study estimates preventable cancer burden linked to poor diet in the US

New study estimates preventable cancer burden linked to poor diet in the US

by Tufts UniversityA new study estimates that 5.2 percent of new invasive cancer cases reported in 2015 are associated with poor diets. Credit: Nako Kobayashi/Tufts UniversityA new modeling study

New study estimates preventable cancer burden linked to poor diet in the US

by Tufts UniversityA new study estimates that 5.2 percent of new invasive cancer cases reported in 2015 are associated with poor diets. Credit: Nako Kobayashi/Tufts UniversityA new modeling study