New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on: May 21,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on:May 21,2024

New biomarker for early prediction of response to CAR-T cell therapy

by Medical University of ViennaCredit: AI-generated imageA MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequ

Updated on: February 01,2024

New biomarker for early prediction of response to CAR-T cell therapy

by Medical University of ViennaCredit: AI-generated imageA MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequ

Updated on:February 01,2024

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on: April 09,2024

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on:April 09,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on: January 02,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on:January 02,2024

Study suggests a way to re-energize tired T cells when treating cancer, viral infections

by Ohio State University Medical CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by researche

Updated on: February 20,2024

Study suggests a way to re-energize tired T cells when treating cancer, viral infections

by Ohio State University Medical CenterScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by researche

Updated on:February 20,2024

Zika virus could help combat brain cancer

by FAPESPStudy by Brazilian researchers shows infection by Zika caused death of cells from glioblastoma, the most common and aggressive kind of malignant brain tumor in adults . Credit: cytopathi

Updated on: March 01,2024

Zika virus could help combat brain cancer

by FAPESPStudy by Brazilian researchers shows infection by Zika caused death of cells from glioblastoma, the most common and aggressive kind of malignant brain tumor in adults . Credit: cytopathi

Updated on:March 01,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on: April 14,2024

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on:April 14,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on: January 02,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on:January 02,2024

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on: May 13,2024

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on:May 13,2024

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Updated on: January 02,2024

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Updated on:January 02,2024

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on: April 30,2024

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on:April 30,2024