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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers create novel compound targeting melanoma cells

Researchers create novel compound targeting melanoma cells

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0An international team of re

Researchers create novel compound targeting melanoma cells

by Boston University School of MedicineMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0An international team of re
Virus-targeting white blood cells in tumors offer intriguing insights into responsiveness to immunotherapy

Virus-targeting white blood cells in tumors offer intriguing insights into responsiveness to immunotherapy

by Agency for Science, Technology and Research (A*STAR), SingaporeGreen and red tumor-infiltrating lymphocytes expressing CD39 in human lung cancer. Credit: A*STAR Singapore Immunology NetworkBys

Virus-targeting white blood cells in tumors offer intriguing insights into responsiveness to immunotherapy

by Agency for Science, Technology and Research (A*STAR), SingaporeGreen and red tumor-infiltrating lymphocytes expressing CD39 in human lung cancer. Credit: A*STAR Singapore Immunology NetworkBys
Researcher and her students discover lesser-known gene associated with breast cancer

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b
70-gene signature impacts treatment decisions in breast CA

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud
Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre
Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

by Adam Pope,University of Alabama at BirminghamProtein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. Th

Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

by Adam Pope,University of Alabama at BirminghamProtein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. Th
Research suggests a new approach for treatment-resistant breast cancers

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15
Team discovers broken 'brake' of cancer mutation machine

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that
Moderate delays safe in treating colon cancer

Moderate delays safe in treating colon cancer

by Paul Mayne,University of Western OntarioSchulich School of Medicine & Dentistry medical resident Dr. Kerollos Wanis, left, assists Drs. David Bottoni and Robert Black with a cancer-resect

Moderate delays safe in treating colon cancer

by Paul Mayne,University of Western OntarioSchulich School of Medicine & Dentistry medical resident Dr. Kerollos Wanis, left, assists Drs. David Bottoni and Robert Black with a cancer-resect
Mutation analysis on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

Mutation analysis on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new research paper was published inOncotargetentitled, "Mutation analysis performed on tumor biopsies from patients with newly

Mutation analysis on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new research paper was published inOncotargetentitled, "Mutation analysis performed on tumor biopsies from patients with newly
Researchers characterize mechanism of action of CAR T cells

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci
Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b