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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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No increased cancer risk found in rheumatology patients with history of malignancy taking DMARDS and TNF inhibitors

No increased cancer risk found in rheumatology patients with history of malignancy taking DMARDS and TNF inhibitors

byAmerican College of RheumatologyFlowchart of patients included in the study. Credit: Cancer Risk with Biologic and Targeted Synthetic DMARDs in Patients with Rheumatic Diseases and Previous Ma

No increased cancer risk found in rheumatology patients with history of malignancy taking DMARDS and TNF inhibitors

byAmerican College of RheumatologyFlowchart of patients included in the study. Credit: Cancer Risk with Biologic and Targeted Synthetic DMARDs in Patients with Rheumatic Diseases and Previous Ma
Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.
Testing method could point thousands more cancer patients to lifesaving treatment

Testing method could point thousands more cancer patients to lifesaving treatment

byUniversity of OklahomaDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHNot all cancer therapies are successful, but cancer researchers increa

Testing method could point thousands more cancer patients to lifesaving treatment

byUniversity of OklahomaDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHNot all cancer therapies are successful, but cancer researchers increa
Ophthalmologic manifestations of acute leukemia are heterogeneous

Ophthalmologic manifestations of acute leukemia are heterogeneous

by Elana GotkineOphthalmologic manifestations of acute leukemia are heterogeneous and detectable at initial presentation or relapse, according to a studypublishedonline July 10 in the&nbsp

Ophthalmologic manifestations of acute leukemia are heterogeneous

by Elana GotkineOphthalmologic manifestations of acute leukemia are heterogeneous and detectable at initial presentation or relapse, according to a studypublishedonline July 10 in the&nbsp
Researchers find a potential therapeutic target to prevent dissemination of cancer cells in the central nervous system

Researchers find a potential therapeutic target to prevent dissemination of cancer cells in the central nervous system

by Instituto de Medicina MolecularGraphical abstract. Credit:Neuro-Oncology Advances(2023). DOI: 10.1093/noajnl/vdad048A new study led by Cláudia C. Faria, researcher in the lab of João Ta

Researchers find a potential therapeutic target to prevent dissemination of cancer cells in the central nervous system

by Instituto de Medicina MolecularGraphical abstract. Credit:Neuro-Oncology Advances(2023). DOI: 10.1093/noajnl/vdad048A new study led by Cláudia C. Faria, researcher in the lab of João Ta
New marker could detect fatal breast cancer up to one year earlier than current methods

New marker could detect fatal breast cancer up to one year earlier than current methods

by BioMed CentralMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainA new marker that could be used to diagnose fatal breast cancer up to one year ah

New marker could detect fatal breast cancer up to one year earlier than current methods

by BioMed CentralMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainA new marker that could be used to diagnose fatal breast cancer up to one year ah
Inherited mutations may play a role in pancreatic cancer development

Inherited mutations may play a role in pancreatic cancer development

by Johns Hopkins University School of MedicineAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA small, retrospective study has found tha

Inherited mutations may play a role in pancreatic cancer development

by Johns Hopkins University School of MedicineAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA small, retrospective study has found tha
Clinical trial of adjuvant therapy combination shows improved recurrence-free survival in liver cancer patients

Clinical trial of adjuvant therapy combination shows improved recurrence-free survival in liver cancer patients

by SingHealthCredit: Pixabay/CC0 Public DomainAn international randomized controlled trial, advised by a steering committee co-led by a senior clinician-scientist from the National Cancer Centre

Clinical trial of adjuvant therapy combination shows improved recurrence-free survival in liver cancer patients

by SingHealthCredit: Pixabay/CC0 Public DomainAn international randomized controlled trial, advised by a steering committee co-led by a senior clinician-scientist from the National Cancer Centre
Discovery of pancreatic neuroendocrine subtypes could help predict likelihood of recurrence

Discovery of pancreatic neuroendocrine subtypes could help predict likelihood of recurrence

by Dana-Farber Cancer InstituteCredit: CC0 Public DomainResearchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors—known as pNETs—that have dramatically different risks

Discovery of pancreatic neuroendocrine subtypes could help predict likelihood of recurrence

by Dana-Farber Cancer InstituteCredit: CC0 Public DomainResearchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors—known as pNETs—that have dramatically different risks
Metachronous pathology assessed in young-onset colorectal cancer survivors

Metachronous pathology assessed in young-onset colorectal cancer survivors

The incidence rate of clinically significant metachronous colorectal pathology is 32 per 1,000 person-years after index young-onset colorectal cancer (YOCRC), according to a research letter published

Metachronous pathology assessed in young-onset colorectal cancer survivors

The incidence rate of clinically significant metachronous colorectal pathology is 32 per 1,000 person-years after index young-onset colorectal cancer (YOCRC), according to a research letter published
First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris
Potential strategy for treating liver cancer: Study discovers signaling pathway mediated by extracellular vesicles

Potential strategy for treating liver cancer: Study discovers signaling pathway mediated by extracellular vesicles

by The University of Hong KongCirculating sEVs from HCC patients promote angiogenesis in vitro and in vivo. A) Tube formation assay of HUVECs pretreated with PBS, circulating sEVs of control indi

Potential strategy for treating liver cancer: Study discovers signaling pathway mediated by extracellular vesicles

by The University of Hong KongCirculating sEVs from HCC patients promote angiogenesis in vitro and in vivo. A) Tube formation assay of HUVECs pretreated with PBS, circulating sEVs of control indi