Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on: February 03,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on:February 03,2024

Fatal brake failures: Tumorigenesis in the colon

by Ludwig Maximilian University of MunichMir34a/p53-deficient metastatic colon cancer cells invading into a lymph node. Brown staining detects high levels of nuclear beta-catenin protein, which i

Updated on: March 08,2024

Fatal brake failures: Tumorigenesis in the colon

by Ludwig Maximilian University of MunichMir34a/p53-deficient metastatic colon cancer cells invading into a lymph node. Brown staining detects high levels of nuclear beta-catenin protein, which i

Updated on:March 08,2024

Outpatient stem cell transplants result in less hospitalization time for multiple myeloma patients, study finds

by Leslie Cantu,Medical University of South CarolinaCredit: Unsplash/CC0 Public DomainMost multiple myeloma patients undergoing stem cell transplants of their own cells can safely be treated in

Updated on: January 23,2024

Outpatient stem cell transplants result in less hospitalization time for multiple myeloma patients, study finds

by Leslie Cantu,Medical University of South CarolinaCredit: Unsplash/CC0 Public DomainMost multiple myeloma patients undergoing stem cell transplants of their own cells can safely be treated in

Updated on:January 23,2024

Accurately diagnosing genetic disease prevents cancer, saves lives

by The Ohio State University Comprehensive Cancer CenterCredit: CC0 Public DomainA single, upfront genomic test is more effective for detecting Lynch syndrome in colorectal cancer (CRC) patients than

Updated on: April 01,2024

Accurately diagnosing genetic disease prevents cancer, saves lives

by The Ohio State University Comprehensive Cancer CenterCredit: CC0 Public DomainA single, upfront genomic test is more effective for detecting Lynch syndrome in colorectal cancer (CRC) patients than

Updated on:April 01,2024

Cancer drug data release set to power next wave of therapeutic discovery

by Wellcome Sanger InstituteCredit: CC0 Public DomainThis week (25 July) the Genomics of Drug Sensitivity in Cancer project has released the results of four years of intense data gathering and explora

Updated on: March 09,2024

Cancer drug data release set to power next wave of therapeutic discovery

by Wellcome Sanger InstituteCredit: CC0 Public DomainThis week (25 July) the Genomics of Drug Sensitivity in Cancer project has released the results of four years of intense data gathering and explora

Updated on:March 09,2024

Researchers exploit DNA amplification in cancer to halt chemoresistance

by Stony Brook UniversityGábor Balázsi, in his Biomedical Engineering laboratory with Rafal Krzysztoń, PhD, and Yiming Wan, PhD, both first co-authors on thePNASpaper. Credit: John Gr

Updated on: June 08,2024

Researchers exploit DNA amplification in cancer to halt chemoresistance

by Stony Brook UniversityGábor Balázsi, in his Biomedical Engineering laboratory with Rafal Krzysztoń, PhD, and Yiming Wan, PhD, both first co-authors on thePNASpaper. Credit: John Gr

Updated on:June 08,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on: June 08,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on:June 08,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on: May 23,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on:May 23,2024

Fred Hutch researchers engineer complex immunotherapy that may target relapsing leukemia

by Fred Hutchinson Cancer Research CenterDr. Marie Bleakley, a pediatric oncologist and researcher at Fred Hutch, is advancing a new approach to genetically engineer T cells. Credit: Fred HutchOc

Updated on: March 06,2024

Fred Hutch researchers engineer complex immunotherapy that may target relapsing leukemia

by Fred Hutchinson Cancer Research CenterDr. Marie Bleakley, a pediatric oncologist and researcher at Fred Hutch, is advancing a new approach to genetically engineer T cells. Credit: Fred HutchOc

Updated on:March 06,2024

Study analyses how far people will travel for specialist cancer care

by University College LondonCredit: Keith Sergeant Source:FlickrPeople are willing to travel 75 minutes longer for specialist cancer surgery if it reduces their risk of complications

Updated on: March 12,2024

Study analyses how far people will travel for specialist cancer care

by University College LondonCredit: Keith Sergeant Source:FlickrPeople are willing to travel 75 minutes longer for specialist cancer surgery if it reduces their risk of complications

Updated on:March 12,2024

Rural residence tied to poorer adherence to radiation treatment for cancer

Rural residence is associated with both radiation treatment (RT) nonadherence and poorer overall survival among cancer patients, according to a study recently published in theInternational Journ

Updated on: January 02,2024

Rural residence tied to poorer adherence to radiation treatment for cancer

Rural residence is associated with both radiation treatment (RT) nonadherence and poorer overall survival among cancer patients, according to a study recently published in theInternational Journ

Updated on:January 02,2024

Study suggests possible way to 'Smac' cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainIn animals, a process of programmed cell death called apoptosis ensures cells die when they should. An opposing force, governed by

Updated on: January 30,2024

Study suggests possible way to 'Smac' cancer

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainIn animals, a process of programmed cell death called apoptosis ensures cells die when they should. An opposing force, governed by

Updated on:January 30,2024