Fatal brake failures: Tumorigenesis in the colon

by Ludwig Maximilian University of MunichMir34a/p53-deficient metastatic colon cancer cells invading into a lymph node. Brown staining detects high levels of nuclear beta-catenin protein, which i

Updated on: March 08,2024 12

Fatal brake failures: Tumorigenesis in the colon

by Ludwig Maximilian University of MunichMir34a/p53-deficient metastatic colon cancer cells invading into a lymph node. Brown staining detects high levels of nuclear beta-catenin protein, which i

Updated on:March 08,2024 12

Research unveils genetic characteristics and improved prognosis of triple-negative apocrine carcinoma

by JooHyeon Heo,Ulsan National Institute of Science and TechnologySomatic Point Mutations in TNAC and LK-TNBC. The top 16 significantly mutated genes as determined by the dNdScv algorithm (p &lt

Updated on: February 18,2024 20

Research unveils genetic characteristics and improved prognosis of triple-negative apocrine carcinoma

by JooHyeon Heo,Ulsan National Institute of Science and TechnologySomatic Point Mutations in TNAC and LK-TNBC. The top 16 significantly mutated genes as determined by the dNdScv algorithm (p &lt

Updated on:February 18,2024 20

Spiritual themes, distrust may factor into Black patients' reluctance to participate in cancer clinical trials

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainSpiritual beliefs and a historically-based distrust of clinical research may factor into Black patients' decisions about whe

Updated on: October 22,2024 0

Spiritual themes, distrust may factor into Black patients' reluctance to participate in cancer clinical trials

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainSpiritual beliefs and a historically-based distrust of clinical research may factor into Black patients' decisions about whe

Updated on:October 22,2024 0

A new hope in immunotherapy against cancer

by Karolinska InstitutetIdentification of SB02024 as a potent and selective inhibitor of VPS34. (A) Chemical structure of SB02024. (B) Cartoon representation of the structure of complex between V

Updated on: April 06,2024 0

A new hope in immunotherapy against cancer

by Karolinska InstitutetIdentification of SB02024 as a potent and selective inhibitor of VPS34. (A) Chemical structure of SB02024. (B) Cartoon representation of the structure of complex between V

Updated on:April 06,2024 0

Oncolytic virus treatment produces promising results in patients with triple-negative breast cancer

byH. Lee Moffitt Cancer Center & Research InstituteCredit: Unsplash/CC0 Public DomainTriple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with th

Updated on: January 02,2024 9

Oncolytic virus treatment produces promising results in patients with triple-negative breast cancer

byH. Lee Moffitt Cancer Center & Research InstituteCredit: Unsplash/CC0 Public DomainTriple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with th

Updated on:January 02,2024 9

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on: April 28,2024 0

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on:April 28,2024 0

Tumor Metabolism Atlas offers a new way to discover cancer mechanisms

byWeill Cornell Medical CollegeCredit: AI-generated imageAn atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifyin

Updated on: January 22,2024 20

Tumor Metabolism Atlas offers a new way to discover cancer mechanisms

byWeill Cornell Medical CollegeCredit: AI-generated imageAn atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifyin

Updated on:January 22,2024 20

Important to be open to discussing sex with young cancer survivors

by University of GothenburgCredit: University of GothenburgFeeling unattractive and dissatisfied with their sexual ability – that is reality for many teenage and young adult cancer survivors. Res

Updated on: March 01,2024 20

Important to be open to discussing sex with young cancer survivors

by University of GothenburgCredit: University of GothenburgFeeling unattractive and dissatisfied with their sexual ability – that is reality for many teenage and young adult cancer survivors. Res

Updated on:March 01,2024 20

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting

Updated on: May 20,2024 8

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting

Updated on:May 20,2024 8

Skin cancer-related mutations higher in the UK than Singapore, new study shows

by Wellcome Trust Sanger InstituteA representation of protein-altering mutations in 1 square centimeter of skin from donors of the UK and Singapore. The UK square contains many more circles. Cred

Updated on: February 23,2024 17

Skin cancer-related mutations higher in the UK than Singapore, new study shows

by Wellcome Trust Sanger InstituteA representation of protein-altering mutations in 1 square centimeter of skin from donors of the UK and Singapore. The UK square contains many more circles. Cred

Updated on:February 23,2024 17

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on: January 02,2024 9

Immune system B-cells can help predict HER2-positive breast cancer treatment response

byUNC Lineberger Comprehensive Cancer CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Ce

Updated on:January 02,2024 9

Study discusses liquid biopsy as a game changer for early lung cancer detection

by Cactus CommunicationsCredit: CC0 Public DomainIn 2020, 1.8 million people succumbed to lung cancer. The late-stage discovery of lung cancer is one of the glaring challenges faced by the medical com

Updated on: March 30,2024 0

Study discusses liquid biopsy as a game changer for early lung cancer detection

by Cactus CommunicationsCredit: CC0 Public DomainIn 2020, 1.8 million people succumbed to lung cancer. The late-stage discovery of lung cancer is one of the glaring challenges faced by the medical com

Updated on:March 30,2024 0