New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on: April 23,2024

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on:April 23,2024

Preventing breast cancer just got easier. Will more women give these drugs a try?

by Melissa Healy, Los Angeles TimesThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on: May 05,2024

Preventing breast cancer just got easier. Will more women give these drugs a try?

by Melissa Healy, Los Angeles TimesThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on:May 05,2024

Researchers to develop handheld device to diagnose skin cancer

by Stevens Institute of TechnologyStevens researchers develop a technique based on reflectivity patterns that can distinguish multiple forms of skin cancer, including basal cell carcinoma (left)

Updated on: June 15,2024

Researchers to develop handheld device to diagnose skin cancer

by Stevens Institute of TechnologyStevens researchers develop a technique based on reflectivity patterns that can distinguish multiple forms of skin cancer, including basal cell carcinoma (left)

Updated on:June 15,2024

New molecular blocker halts breast cancer metastasis, says study

byBar-Ilan UniversityA cell-permeable peptide derived from the second proline-rich region of Pyk2 blocks spontaneous lung metastasis in an immune-competent xenograft mouse model. Credit:On

Updated on: January 16,2024

New molecular blocker halts breast cancer metastasis, says study

byBar-Ilan UniversityA cell-permeable peptide derived from the second proline-rich region of Pyk2 blocks spontaneous lung metastasis in an immune-competent xenograft mouse model. Credit:On

Updated on:January 16,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on: January 02,2024

Immune targets for chemotherapy-resistant breast cancers identified

byKing's College LondonAnalysis of stromal TILs in residual disease and prognostic implications. A) Kaplan–Meier curves for i) progression free survival and ii) overall survival in ER+HER2-

Updated on:January 02,2024

Researchers develop novel photo-oxidation therapy for anticancer treatment

by City University of Hong KongThe CityU team developed a new class of near-infrared-activated platinum(IV) photo-oxidants that can effectively eliminate cancer cells in an oxygen-independent man

Updated on: June 08,2024

Researchers develop novel photo-oxidation therapy for anticancer treatment

by City University of Hong KongThe CityU team developed a new class of near-infrared-activated platinum(IV) photo-oxidants that can effectively eliminate cancer cells in an oxygen-independent man

Updated on:June 08,2024

Discovery paves way for precision medicine in future

by University of OtagoThis high-dimensional analysis reveals the T cell signature in people with bowel cancer. The new analysis groups cells together so all cells can be viewed at once. In the pa

Updated on: April 18,2024

Discovery paves way for precision medicine in future

by University of OtagoThis high-dimensional analysis reveals the T cell signature in people with bowel cancer. The new analysis groups cells together so all cells can be viewed at once. In the pa

Updated on:April 18,2024

Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on: April 07,2024

Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on:April 07,2024

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b

Updated on: March 01,2024

Researcher and her students discover lesser-known gene associated with breast cancer

by Villanova UniversityCredit: Villanova UniversityVillanova University biology professor Janice Knepper, PhD, and her students have discovered that a gene, previously poorly characterized, can b

Updated on:March 01,2024

Old chemo drug, new pancreatic cancer therapy?

Updated on: September 10,2024

Old chemo drug, new pancreatic cancer therapy?

Updated on:September 10,2024

Study outlines targeted treatment option for aggressive breast cancer

by University of MarylandMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainNew findings put forth by the University of Maryland Fischell Department

Updated on: March 01,2024

Study outlines targeted treatment option for aggressive breast cancer

by University of MarylandMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainNew findings put forth by the University of Maryland Fischell Department

Updated on:March 01,2024

Metachronous pathology assessed in young-onset colorectal cancer survivors

The incidence rate of clinically significant metachronous colorectal pathology is 32 per 1,000 person-years after index young-onset colorectal cancer (YOCRC), according to a research letter published

Updated on: January 02,2024

Metachronous pathology assessed in young-onset colorectal cancer survivors

The incidence rate of clinically significant metachronous colorectal pathology is 32 per 1,000 person-years after index young-onset colorectal cancer (YOCRC), according to a research letter published

Updated on:January 02,2024