An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on: March 06,2024

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on:March 06,2024

No substantial benefit from transplantation reported for a high-risk leukemia subtype

by St. Jude Children's Research HospitalA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA

Updated on: May 13,2024

No substantial benefit from transplantation reported for a high-risk leukemia subtype

by St. Jude Children's Research HospitalA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA

Updated on:May 13,2024

Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

by Salk InstituteCredit: Human Brain ProjectGlioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous

Updated on: February 24,2024

Study shows the benefit of harnessing the body's own immune cells to fight brain cancer

by Salk InstituteCredit: Human Brain ProjectGlioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous

Updated on:February 24,2024

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Updated on: January 02,2024

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Updated on:January 02,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on: February 01,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on:February 01,2024

Researchers discover crucial step in creating blood stem cells

by Iowa State UniversityBlood stem cells show forming in the trunk of a zebrafish embryo. The blood stem cells are yellow, with the red tubes are the aorta on the top and a vein on the bottom. Cr

Updated on: February 03,2024

Researchers discover crucial step in creating blood stem cells

by Iowa State UniversityBlood stem cells show forming in the trunk of a zebrafish embryo. The blood stem cells are yellow, with the red tubes are the aorta on the top and a vein on the bottom. Cr

Updated on:February 03,2024

Ewing sarcoma tumors can be split into two groups for targeted care

by Cincinnati Children's Hospital Medical CenterA. Bright field images of CCH1 and CCH2 cells B. CCH1 and CCH2 cells cells stained with antibody towards CD99 (green) and DAPI (blue) C. Wester

Updated on: February 03,2024

Ewing sarcoma tumors can be split into two groups for targeted care

by Cincinnati Children's Hospital Medical CenterA. Bright field images of CCH1 and CCH2 cells B. CCH1 and CCH2 cells cells stained with antibody towards CD99 (green) and DAPI (blue) C. Wester

Updated on:February 03,2024

Head and neck cancer researchers demonstrate the capability of a deep learning algorithm in the post-surgery setting

by ECOG-ACRIN Cancer Research Group"This type of research is key since it can help identify patients with high-risk, aggressive head and neck cancer, and also help select appropriate patients for

Updated on: January 07,2024

Head and neck cancer researchers demonstrate the capability of a deep learning algorithm in the post-surgery setting

by ECOG-ACRIN Cancer Research Group"This type of research is key since it can help identify patients with high-risk, aggressive head and neck cancer, and also help select appropriate patients for

Updated on:January 07,2024

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on: January 23,2024

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on:January 23,2024

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

Updated on: March 14,2024

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

Updated on:March 14,2024

Suicide risk more than quadruples for people with cancer

by Pennsylvania State UniversityCredit: CC0 Public DomainPeople with cancer are more than four times more likely to commit suicide than people without cancer, according to Penn State College of M

Updated on: March 06,2024

Suicide risk more than quadruples for people with cancer

by Pennsylvania State UniversityCredit: CC0 Public DomainPeople with cancer are more than four times more likely to commit suicide than people without cancer, according to Penn State College of M

Updated on:March 06,2024