Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on: May 27,2024 3

Study: Drugs reprogram genes in breast tumors to prevent endocrine resistance

by Sharita Forrest,University of Illinois at Urbana-ChampaignTargeting estrogen receptor-positive breast tumors with the XPO1 antagonist selinexor and the tamoxifen byproduct 4-OHT simultaneousl

Updated on:May 27,2024 3

First-line pembrolizumab plus chemotherapy may benefit patients with advanced biliary tract cancers

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainThe addition of pembrolizumab (Keytruda) to gemcitabine and cisplatin improved overall survival in patients with untrea

Updated on: January 30,2024 19

First-line pembrolizumab plus chemotherapy may benefit patients with advanced biliary tract cancers

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainThe addition of pembrolizumab (Keytruda) to gemcitabine and cisplatin improved overall survival in patients with untrea

Updated on:January 30,2024 19

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on: May 13,2024 5

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on:May 13,2024 5

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on: January 12,2024 12

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on:January 12,2024 12

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on: February 18,2024 14

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on:February 18,2024 14

Researchers apply fat cells to deliver drug to suppress tumor growth

by University of California, Los AngelesCredit: CC0 Public DomainResearchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor g

Updated on: March 08,2024 14

Researchers apply fat cells to deliver drug to suppress tumor growth

by University of California, Los AngelesCredit: CC0 Public DomainResearchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor g

Updated on:March 08,2024 14

Exercise can reduce severity of breast cancer treatment side effects

by Edith Cowan UniversityCredit: Pixabay/CC0 Public DomainBreast cancer is the most common form of the disease among women; in Australia, one in eight women will be diagnosed with breast cancer b

Updated on: February 03,2024 13

Exercise can reduce severity of breast cancer treatment side effects

by Edith Cowan UniversityCredit: Pixabay/CC0 Public DomainBreast cancer is the most common form of the disease among women; in Australia, one in eight women will be diagnosed with breast cancer b

Updated on:February 03,2024 13

Tumor resistance is promoted by anti-cancer protein

by Champalimaud Centre for the UnknownCredit: CC0 Public DomainLack of oxygen, or hypoxia, is a biological stressor that occurs under various conditions such as wound healing and stroke. To rescue the

Updated on: April 09,2024 12

Tumor resistance is promoted by anti-cancer protein

by Champalimaud Centre for the UnknownCredit: CC0 Public DomainLack of oxygen, or hypoxia, is a biological stressor that occurs under various conditions such as wound healing and stroke. To rescue the

Updated on:April 09,2024 12

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on: April 23,2024 0

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

Updated on:April 23,2024 0

Researchers describe a mechanism inducing self-killing of cancer cells

by The Korea Advanced Institute of Science and Technology (KAIST)Professor Kim (left) and lead author Lee. Credit: The Korea Advanced Institute of Science and Technology (KAIST)Researchers have d

Updated on: June 08,2024 3

Researchers describe a mechanism inducing self-killing of cancer cells

by The Korea Advanced Institute of Science and Technology (KAIST)Professor Kim (left) and lead author Lee. Credit: The Korea Advanced Institute of Science and Technology (KAIST)Researchers have d

Updated on:June 08,2024 3

In the eye of the medulloblastoma

by CNRSThe medulloblastoma expresses genes normally active in the retina only, including NRL and CRX, which play a role in the formation of the tumor. Credit: Morgane Morabito / UMR3347 CNRS-Inst

Updated on: March 01,2024 18

In the eye of the medulloblastoma

by CNRSThe medulloblastoma expresses genes normally active in the retina only, including NRL and CRX, which play a role in the formation of the tumor. Credit: Morgane Morabito / UMR3347 CNRS-Inst

Updated on:March 01,2024 18

Combined breast and gynecologic surgery: Study says not so fast

by Garth Sundem,CU Anschutz Medical CampusSarah Tevis, MD. Credit: University of ColoradoBreast cancer patients and women undergoing cancer-preventive breast surgeries may consider combining the

Updated on: March 06,2024 11

Combined breast and gynecologic surgery: Study says not so fast

by Garth Sundem,CU Anschutz Medical CampusSarah Tevis, MD. Credit: University of ColoradoBreast cancer patients and women undergoing cancer-preventive breast surgeries may consider combining the

Updated on:March 06,2024 11