Study of immune 'neighborhoods' highlights macrophages as key players in invasive breast cancers

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainMost immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targ

Updated on: January 02,2024

Study of immune 'neighborhoods' highlights macrophages as key players in invasive breast cancers

byUniversity of PittsburghCredit: Unsplash/CC0 Public DomainMost immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targ

Updated on:January 02,2024

Patient-derived organoids in human cancer: A platform for fundamental research and precision medicine

by Sichuan International Medical Exchange and Promotion AssociationThe GBM organoids culture process and subsequent analysis are illustrated schematically. A rapid and dependable technique has been de

Updated on: March 30,2024

Patient-derived organoids in human cancer: A platform for fundamental research and precision medicine

by Sichuan International Medical Exchange and Promotion AssociationThe GBM organoids culture process and subsequent analysis are illustrated schematically. A rapid and dependable technique has been de

Updated on:March 30,2024

Researchers use EHRs to identify cancer symptom clusters

by Regenstrief InstituteKun Huang, Ph.D. of Regenstrief Institute and Indiana University School of Medicine and Xiao Luo, Ph.D.of IUPUI conducted a study using electronic health records to identi

Updated on: June 06,2024

Researchers use EHRs to identify cancer symptom clusters

by Regenstrief InstituteKun Huang, Ph.D. of Regenstrief Institute and Indiana University School of Medicine and Xiao Luo, Ph.D.of IUPUI conducted a study using electronic health records to identi

Updated on:June 06,2024

Medicare to cover CAR-T therapy for leukemia, lymphoma

A breakthrough gene therapy will be covered for certain types of lymphoma and leukemia, Medicare says.Chimeric antigen receptor T-cell (CAR-T)therapyboosts a patient's own immune cells

Updated on: May 17,2024

Medicare to cover CAR-T therapy for leukemia, lymphoma

A breakthrough gene therapy will be covered for certain types of lymphoma and leukemia, Medicare says.Chimeric antigen receptor T-cell (CAR-T)therapyboosts a patient's own immune cells

Updated on:May 17,2024

Study outlines targeted treatment option for aggressive breast cancer

by University of MarylandMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainNew findings put forth by the University of Maryland Fischell Department

Updated on: March 01,2024

Study outlines targeted treatment option for aggressive breast cancer

by University of MarylandMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainNew findings put forth by the University of Maryland Fischell Department

Updated on:March 01,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on: February 03,2024

Everolimus inhibits angiogenesis and lymphangiogenesis in TP53 mutant HNSCC via STAT3/HIF-1α/VEGF pathway

by Impact Journals LLCEverolimus reduces microvessel density (MVD) and lymphatic vessel density (LVD) in TP53 mutant HNSCC xenografts. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.283

Updated on:February 03,2024

Maximizing the potential of 3D-patient tumor avatars for next-generation precision oncology

by Terasaki Institute for Biomedical Innovation3D Patient Tumor Avatars (3D-PTAs) are part of a proposed integrative platform to provide optimal treatment selections for cancer patients. Such a platfo

Updated on: January 21,2024

Maximizing the potential of 3D-patient tumor avatars for next-generation precision oncology

by Terasaki Institute for Biomedical Innovation3D Patient Tumor Avatars (3D-PTAs) are part of a proposed integrative platform to provide optimal treatment selections for cancer patients. Such a platfo

Updated on:January 21,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on: March 30,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on:March 30,2024

New test predicts chance of living more than a year on targeted breast cancer treatment

by Institute of Cancer ResearchBreast cancer cells stained for DNA (red), NFkB (green), and a reactive oxygen species probe (blue). Credit: Julia Sero / the ICR, 2011A new test could pick out wom

Updated on: May 23,2024

New test predicts chance of living more than a year on targeted breast cancer treatment

by Institute of Cancer ResearchBreast cancer cells stained for DNA (red), NFkB (green), and a reactive oxygen species probe (blue). Credit: Julia Sero / the ICR, 2011A new test could pick out wom

Updated on:May 23,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on: February 23,2024

Discovery could lead to new drugs to block protein that fuels bowel cancer

by Institute of Cancer ResearchUsing cryo-electron microscopy, researchers obtained a detailed map (shown in orange) of the chain-like tankyrase structure. By interpreting this map and reconstruc

Updated on:February 23,2024

A new therapeutic target for metastatic and resistant prostate cancers

by IDIBELL-Bellvitge Biomedical Research InstituteÁlvaro Aytés & Katia Ruggero. Credit: IDIBELLProstate Cancer researchers from the Bellvitge Biomedical Research Institute (IDIBELL), led by D

Updated on: April 01,2024

A new therapeutic target for metastatic and resistant prostate cancers

by IDIBELL-Bellvitge Biomedical Research InstituteÁlvaro Aytés & Katia Ruggero. Credit: IDIBELLProstate Cancer researchers from the Bellvitge Biomedical Research Institute (IDIBELL), led by D

Updated on:April 01,2024

Shortages of essential medicines for pediatric cancer patients threaten outcomes

by Baylor College of MedicineCredit: CC0 Public DomainShortages of essential chemotherapy drugs for children undergoing cancer treatment has been an increasingly frequent obstacle for patients an

Updated on: March 06,2024

Shortages of essential medicines for pediatric cancer patients threaten outcomes

by Baylor College of MedicineCredit: CC0 Public DomainShortages of essential chemotherapy drugs for children undergoing cancer treatment has been an increasingly frequent obstacle for patients an

Updated on:March 06,2024