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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers identify new therapeutic approach to preventing cancer from spreading to the brain

Researchers identify new therapeutic approach to preventing cancer from spreading to the brain

byMcMaster UniversityCredit: CC0 Public DomainIn a studypublishedin the journalCell Reports Medicine, researchers Sheila Singh and Jakob Magolan discovered a critical vulnerabi

Researchers identify new therapeutic approach to preventing cancer from spreading to the brain

byMcMaster UniversityCredit: CC0 Public DomainIn a studypublishedin the journalCell Reports Medicine, researchers Sheila Singh and Jakob Magolan discovered a critical vulnerabi
Novel treatment effective for bladder cancer, study in mice shows

Novel treatment effective for bladder cancer, study in mice shows

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainAn epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by

Novel treatment effective for bladder cancer, study in mice shows

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainAn epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by
A new tool to screen drugs that target loss of tumor suppressor genes

A new tool to screen drugs that target loss of tumor suppressor genes

by Ludwig Cancer ResearchGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104437In a May publication iniScience, researchers led by Ludwig Johns Hopkins's

A new tool to screen drugs that target loss of tumor suppressor genes

by Ludwig Cancer ResearchGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104437In a May publication iniScience, researchers led by Ludwig Johns Hopkins's
Researchers develop an improved hereditary cancer test

Researchers develop an improved hereditary cancer test

by University of British ColumbiaCredit:Cell Genomics(2022). DOI: 10.1016/j.xgen.2022.100233Researchers at the BC Cancer Research Institute have made an advancement in genetic testing

Researchers develop an improved hereditary cancer test

by University of British ColumbiaCredit:Cell Genomics(2022). DOI: 10.1016/j.xgen.2022.100233Researchers at the BC Cancer Research Institute have made an advancement in genetic testing
Blocking key pathways is a way to defeat cancer stem cells

Blocking key pathways is a way to defeat cancer stem cells

by RIKENCancer cell during cell division. Credit: National Institutes of HealthScientists from the RIKEN Center for Integrative Medical Sciences in Japan and international collaborators have foun

Blocking key pathways is a way to defeat cancer stem cells

by RIKENCancer cell during cell division. Credit: National Institutes of HealthScientists from the RIKEN Center for Integrative Medical Sciences in Japan and international collaborators have foun
Prostate cancer 'test by request' policies drive overdiagnosis and inequity with minimal benefit, argue experts

Prostate cancer 'test by request' policies drive overdiagnosis and inequity with minimal benefit, argue experts

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainMost high income countries, including the U.K., do not have a national prostate cancer screening program, but instead allow men without

Prostate cancer 'test by request' policies drive overdiagnosis and inequity with minimal benefit, argue experts

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainMost high income countries, including the U.K., do not have a national prostate cancer screening program, but instead allow men without
Drug combination provides a one-two punch attack against colorectal cancer

Drug combination provides a one-two punch attack against colorectal cancer

by National Cancer InstituteOn the left,SN38, the active metabolite of irinotecan, traps TOP1 on DNA, forming TOP1 cleavage complexes that are degraded upon their formation, as seen by the

Drug combination provides a one-two punch attack against colorectal cancer

by National Cancer InstituteOn the left,SN38, the active metabolite of irinotecan, traps TOP1 on DNA, forming TOP1 cleavage complexes that are degraded upon their formation, as seen by the
Study links mutations in notch gene to role in B cell cancers

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen

Study links mutations in notch gene to role in B cell cancers

by Perelman School of Medicine at the University of PennsylvaniaPeripheral blood with chronic lymphocytic leukemia cells. Credit: Jon Aster, Harvard Medical SchoolNotch is one of the most frequen
DDX41 and its unique contribution to myeloid leukemogenesis

DDX41 and its unique contribution to myeloid leukemogenesis

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainIn an editorial paper published inOncotargettitled, "DDX41 and its unique contribution to myeloid leukemogenesis," researc

DDX41 and its unique contribution to myeloid leukemogenesis

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainIn an editorial paper published inOncotargettitled, "DDX41 and its unique contribution to myeloid leukemogenesis," researc
Tumor microbiome linked to immunotherapy success in sarcoma patients

Tumor microbiome linked to immunotherapy success in sarcoma patients

by Stephanie Winn,UC DavisSoft tissue sarcomas intratumoral microbiome at diagnosis may link with prognosis. (A) Representative gross examination of extremity synovial sarcoma specimen; asterisk

Tumor microbiome linked to immunotherapy success in sarcoma patients

by Stephanie Winn,UC DavisSoft tissue sarcomas intratumoral microbiome at diagnosis may link with prognosis. (A) Representative gross examination of extremity synovial sarcoma specimen; asterisk
AI tool 'DeepHRD' accelerates cancer treatment decisions

AI tool 'DeepHRD' accelerates cancer treatment decisions

byUniversity of California - San DiegoFirst author Erik Bergstrom showcasing a biopsy analysis completed with DeepHRD, a new artificial intelligence tool that can detect clinically actionable ge

AI tool 'DeepHRD' accelerates cancer treatment decisions

byUniversity of California - San DiegoFirst author Erik Bergstrom showcasing a biopsy analysis completed with DeepHRD, a new artificial intelligence tool that can detect clinically actionable ge
Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman