Development of a novel bispecific antibody therapy to overcome myeloma heterogeneity

by Ehime UniversityMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Multiple myeloma is still an incurable hematological ma

Updated on: March 25,2024 18

Development of a novel bispecific antibody therapy to overcome myeloma heterogeneity

by Ehime UniversityMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Multiple myeloma is still an incurable hematological ma

Updated on:March 25,2024 18

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on: April 09,2024 20

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on:April 09,2024 20

Lymphoma patients at high risk of infections after diagnosis

byUppsala UniversityGraphical abstract. Credit:HemaSphere(2024). DOI: 10.1002/hem3.121Every year, around 100 people are affected by mantle cell lymphoma. A study at Uppsala Universit

Updated on: July 09,2024 0

Lymphoma patients at high risk of infections after diagnosis

byUppsala UniversityGraphical abstract. Credit:HemaSphere(2024). DOI: 10.1002/hem3.121Every year, around 100 people are affected by mantle cell lymphoma. A study at Uppsala Universit

Updated on:July 09,2024 0

Cancer survivors who quit smoking found to have 36% lower cardiovascular risk than those who continue

byEuropean Society of CardiologyCredit: Pixabay/CC0 Public DomainCancer patients who continue smoking after their diagnosis have a nearly doubled risk of heart attack, stroke or death due to car

Updated on: January 23,2024 20

Cancer survivors who quit smoking found to have 36% lower cardiovascular risk than those who continue

byEuropean Society of CardiologyCredit: Pixabay/CC0 Public DomainCancer patients who continue smoking after their diagnosis have a nearly doubled risk of heart attack, stroke or death due to car

Updated on:January 23,2024 20

Researcher recommends tailoring colorectal cancer screening for 45-to-49-year-olds

by Regenstrief InstituteCredit: Pixabay/CC0 Public DomainIt's been a year since national recommendations issued by the American Cancer Society and the U.S. Multi-Society Task Force called for

Updated on: January 30,2024 20

Researcher recommends tailoring colorectal cancer screening for 45-to-49-year-olds

by Regenstrief InstituteCredit: Pixabay/CC0 Public DomainIt's been a year since national recommendations issued by the American Cancer Society and the U.S. Multi-Society Task Force called for

Updated on:January 30,2024 20

New research sheds light on how mesothelioma develops

byUniversity of MarylandAn asbestos fiber (stained blue) in lung tissue being surrounded by macrophages. Credit: Centers for Disease Control and PreventionMesothelioma has been a high-profile di

Updated on: January 13,2024 19

New research sheds light on how mesothelioma develops

byUniversity of MarylandAn asbestos fiber (stained blue) in lung tissue being surrounded by macrophages. Credit: Centers for Disease Control and PreventionMesothelioma has been a high-profile di

Updated on:January 13,2024 19

Most survivors of childhood cancer don't get the tests needed to detect serious long-term adverse effects, finds study

by Canadian Medical Association JournalCredit: CC0 Public DomainSurviving childhood cancer does not always mean a clean bill of health, as the treatments that eradicate those cancers can put adul

Updated on: March 20,2024 10

Most survivors of childhood cancer don't get the tests needed to detect serious long-term adverse effects, finds study

by Canadian Medical Association JournalCredit: CC0 Public DomainSurviving childhood cancer does not always mean a clean bill of health, as the treatments that eradicate those cancers can put adul

Updated on:March 20,2024 10

Research: Subset of breast cancers have two PIK3CA mutations on the same allele

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers affiliated with a large number of institutions in the U.S. has found that a subgroup of breast cancers have two PIK3CA mutat

Updated on: June 01,2024 4

Research: Subset of breast cancers have two PIK3CA mutations on the same allele

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers affiliated with a large number of institutions in the U.S. has found that a subgroup of breast cancers have two PIK3CA mutat

Updated on:June 01,2024 4

Exploring ways to overcome cisplatin resistance and alleviate pain in cancer treatment

by Korea University College of MedicineThe study reveals that the transcription factor NANOG activates the transient receptor potential vanilloid 1 (TRPV1)—causing neuropathic pain. TRPV1 further stim

Updated on: January 07,2024 7

Exploring ways to overcome cisplatin resistance and alleviate pain in cancer treatment

by Korea University College of MedicineThe study reveals that the transcription factor NANOG activates the transient receptor potential vanilloid 1 (TRPV1)—causing neuropathic pain. TRPV1 further stim

Updated on:January 07,2024 7

Examining the factors in air pollution that can lead to lung cancer

by Bob Yirka , Medical XpressCredit: Unsplash/CC0 Public DomainA large international team of researchers has found that most lung cancers that result from exposure to air pollution are not due to indu

Updated on: January 28,2024 16

Examining the factors in air pollution that can lead to lung cancer

by Bob Yirka , Medical XpressCredit: Unsplash/CC0 Public DomainA large international team of researchers has found that most lung cancers that result from exposure to air pollution are not due to indu

Updated on:January 28,2024 16

Identifying cancer genes' multiple personalities

byCold Spring Harbor LaboratoryAn up-close look at a mouse's liver; the cells with dark centers were turned cancerous using a new gene-editing strategy devised by Semir Beyaz's lab. Cred

Updated on: January 04,2024 15

Identifying cancer genes' multiple personalities

byCold Spring Harbor LaboratoryAn up-close look at a mouse's liver; the cells with dark centers were turned cancerous using a new gene-editing strategy devised by Semir Beyaz's lab. Cred

Updated on:January 04,2024 15

Two genomic studies could yield more effective, less toxic immunotherapies

by Institut CurieTE-Exon splicing junctions can help differentiate tumors from healthy tissue. Credit: Verge Scientific Communications / Antonela Merlotti / Marianne Burbage / Benjamin SadaccaMnemo Th

Updated on: December 28,2023 10

Two genomic studies could yield more effective, less toxic immunotherapies

by Institut CurieTE-Exon splicing junctions can help differentiate tumors from healthy tissue. Credit: Verge Scientific Communications / Antonela Merlotti / Marianne Burbage / Benjamin SadaccaMnemo Th

Updated on:December 28,2023 10