CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on: April 09,2024 20

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on:April 09,2024 20

New treatment could increase lung cancer survival

byHudson Institute of Medical ResearchMYC-expression drives platinum resistance in vivo. A Schematic overview of experimental approach. B Representative CT images of RPM mice at time-points foll

Updated on: January 13,2024 13

New treatment could increase lung cancer survival

byHudson Institute of Medical ResearchMYC-expression drives platinum resistance in vivo. A Schematic overview of experimental approach. B Representative CT images of RPM mice at time-points foll

Updated on:January 13,2024 13

A new treatment for acute myeloid leukemia could prove beneficial for even more people

by Peter MacCallum Cancer CentreAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainNew research published inScience Advancestoday conducted by researchers at Peter MacCallu

Updated on: February 20,2024 10

A new treatment for acute myeloid leukemia could prove beneficial for even more people

by Peter MacCallum Cancer CentreAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainNew research published inScience Advancestoday conducted by researchers at Peter MacCallu

Updated on:February 20,2024 10

New insights into treating a rare leukemia

by Children's Hospital Los AngelesBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaA study at Children's Hospital Los Angeles is sheddi

Updated on: April 10,2024 19

New insights into treating a rare leukemia

by Children's Hospital Los AngelesBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaA study at Children's Hospital Los Angeles is sheddi

Updated on:April 10,2024 19

Fine-tuning 3D lab-grown mini tumors to help predict how patients respond to cancer therapies

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainScientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organ

Updated on: January 08,2024 9

Fine-tuning 3D lab-grown mini tumors to help predict how patients respond to cancer therapies

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainScientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organ

Updated on:January 08,2024 9

New radiation therapy delays brain cancer regrowth, protects healthy tissue

by Jeanna Vazquez,University of California - San DiegoEach therapeutic seed, approximately the size of a postage stamp, contains radiation sources embedded in a collagen tile that together deliv

Updated on: January 11,2024 10

New radiation therapy delays brain cancer regrowth, protects healthy tissue

by Jeanna Vazquez,University of California - San DiegoEach therapeutic seed, approximately the size of a postage stamp, contains radiation sources embedded in a collagen tile that together deliv

Updated on:January 11,2024 10

Novel drug combination shows promise for advanced HER2-negative breast cancer

by Johns Hopkins University School of MedicineClinical efficacy.a–c, Responses as shown by a waterfall plot (a), swimmers plot (b) and spider plot (c). The dashed lines correspond to +20% a

Updated on: May 09,2024 4

Novel drug combination shows promise for advanced HER2-negative breast cancer

by Johns Hopkins University School of MedicineClinical efficacy.a–c, Responses as shown by a waterfall plot (a), swimmers plot (b) and spider plot (c). The dashed lines correspond to +20% a

Updated on:May 09,2024 4

Finding and targeting a tumor's sweet spot to eradicate aggressive form of leukemia

byUniversity of BirminghamCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113568A highly aggressive common form of leukemia which is activated by mutations in signaling molecul

Updated on: December 28,2023 13

Finding and targeting a tumor's sweet spot to eradicate aggressive form of leukemia

byUniversity of BirminghamCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113568A highly aggressive common form of leukemia which is activated by mutations in signaling molecul

Updated on:December 28,2023 13

Researchers discover the role of RNF114B, a key gene in the progression and treatment of lung adenocarcinoma

byUniversitat Pompeu Fabra - BarcelonaA mouse fibroblast with altered RNF144B expression divides without correctly grouping chromosomes (stained blue), resulting in aberrant cells. Credit: UPFRe

Updated on: July 09,2024 0

Researchers discover the role of RNF114B, a key gene in the progression and treatment of lung adenocarcinoma

byUniversitat Pompeu Fabra - BarcelonaA mouse fibroblast with altered RNF144B expression divides without correctly grouping chromosomes (stained blue), resulting in aberrant cells. Credit: UPFRe

Updated on:July 09,2024 0

Bioengineers combine lab-on-a-chip technology with AI to improve cancer immunotherapy

byIndiana UniversityTheplatform tracks T cell infiltration of tumor spheroids, which are 3D structures made of cancer cells. Credit: Feng GuoAn interdisciplinary team of researchers led by

Updated on: January 04,2024 9

Bioengineers combine lab-on-a-chip technology with AI to improve cancer immunotherapy

byIndiana UniversityTheplatform tracks T cell infiltration of tumor spheroids, which are 3D structures made of cancer cells. Credit: Feng GuoAn interdisciplinary team of researchers led by

Updated on:January 04,2024 9

AI-powered ultrasound imaging that detects breast cancer

by Pohang University of Science & Technology (POSTECH)Research Image. Credit: POSTECHBreast cancer undisputedly has the highest incidence rate in female patients. Moreover, out of the six major ca

Updated on: February 19,2024 19

AI-powered ultrasound imaging that detects breast cancer

by Pohang University of Science & Technology (POSTECH)Research Image. Credit: POSTECHBreast cancer undisputedly has the highest incidence rate in female patients. Moreover, out of the six major ca

Updated on:February 19,2024 19

New tool pinpoints gaps in awareness of blood cancer symptoms

byUniversity of SurreySymptom awareness. *Cough was included as a non-blood cancer symptom. Credit:BMC Cancer(2023). DOI: 10.1186/s12885-023-11149-xA new tool could help identify gap

Updated on: January 13,2024 11

New tool pinpoints gaps in awareness of blood cancer symptoms

byUniversity of SurreySymptom awareness. *Cough was included as a non-blood cancer symptom. Credit:BMC Cancer(2023). DOI: 10.1186/s12885-023-11149-xA new tool could help identify gap

Updated on:January 13,2024 11