New model shows potential for human papillomavirus vaccination switch to 1-dose gender-neutral approach

byCanadian Medical Association JournalCredit: Unsplash/CC0 Public DomainCanadian vaccination programs could switch to a 1-dose gender-neutral human papillomavirus (HPV) vaccination approach and

Updated on: November 11,2024

New model shows potential for human papillomavirus vaccination switch to 1-dose gender-neutral approach

byCanadian Medical Association JournalCredit: Unsplash/CC0 Public DomainCanadian vaccination programs could switch to a 1-dose gender-neutral human papillomavirus (HPV) vaccination approach and

Updated on:November 11,2024

Research links development of childhood leukaemia to mistakes by the immune system

by University of LeedsA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaGenetic mutations that drive the

Updated on: July 02,2024

Research links development of childhood leukaemia to mistakes by the immune system

by University of LeedsA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaGenetic mutations that drive the

Updated on:July 02,2024

New hope for prostate cancer: New form of immunotherapy could prevent resistance to hormone therapy

byUniversity of SheffieldADT stimulates the PV accumulation of FR-β+ TAMs in mouse (Myc-CaP) and localized, human prostate tumors. Credit:Journal for ImmunoTherapy of Cancer(2024). D

Updated on: August 28,2024

New hope for prostate cancer: New form of immunotherapy could prevent resistance to hormone therapy

byUniversity of SheffieldADT stimulates the PV accumulation of FR-β+ TAMs in mouse (Myc-CaP) and localized, human prostate tumors. Credit:Journal for ImmunoTherapy of Cancer(2024). D

Updated on:August 28,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on: February 24,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on:February 24,2024

Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on: January 04,2024

Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on:January 04,2024

Circular RNAs—the new frontier in cancer research

byFlinders UniversityCircular RNA biogenesis and how they are dysregulated in cancer. Credit:Nature Reviews Cancer(2024). DOI: 10.1038/s41568-024-00721-7Unraveling the complexities o

Updated on: August 27,2024

Circular RNAs—the new frontier in cancer research

byFlinders UniversityCircular RNA biogenesis and how they are dysregulated in cancer. Credit:Nature Reviews Cancer(2024). DOI: 10.1038/s41568-024-00721-7Unraveling the complexities o

Updated on:August 27,2024

Overcoming the limits of immunotherapies

byUniversity of WürzburgKarl Petri (left) is setting up an Emmy Noether research group at the University Hospital of Würzburg with the support of the German Research Foundation. Alexandre Truber

Updated on: August 27,2024

Overcoming the limits of immunotherapies

byUniversity of WürzburgKarl Petri (left) is setting up an Emmy Noether research group at the University Hospital of Würzburg with the support of the German Research Foundation. Alexandre Truber

Updated on:August 27,2024

Study shows how morphine may contribute to bone loss and cancer-induced bone pain

by Stacy Pigott,University of ArizonaOn the left, cells isolated from breast cancer cells were treated with RANKL, a growth factor that stimulates bone resorption, to produce osteoclasts (pink).

Updated on: January 22,2024

Study shows how morphine may contribute to bone loss and cancer-induced bone pain

by Stacy Pigott,University of ArizonaOn the left, cells isolated from breast cancer cells were treated with RANKL, a growth factor that stimulates bone resorption, to produce osteoclasts (pink).

Updated on:January 22,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on: March 12,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on:March 12,2024

Creating a 'parts list' for cancer's spread, with help from a worm

by Duke UniversityA tiny worm cell breaking through the wall that normally holds cells in place. Credit:Development(2023). DOI: 10.1242/dev.201570What makes some cancer cells stay put

Updated on: January 30,2024

Creating a 'parts list' for cancer's spread, with help from a worm

by Duke UniversityA tiny worm cell breaking through the wall that normally holds cells in place. Credit:Development(2023). DOI: 10.1242/dev.201570What makes some cancer cells stay put

Updated on:January 30,2024

Researchers unlock mysteries of complex microRNA oncogenes

by McGill UniversityMicroRNA and mRNA visualization in differentiating C1C12 cells. Credit: Ryan Jeffs/WikipediaMicroRNAs are tiny molecules of nucleic acid that control gene expression, acting l

Updated on: June 11,2024

Researchers unlock mysteries of complex microRNA oncogenes

by McGill UniversityMicroRNA and mRNA visualization in differentiating C1C12 cells. Credit: Ryan Jeffs/WikipediaMicroRNAs are tiny molecules of nucleic acid that control gene expression, acting l

Updated on:June 11,2024