Using cryo-shocked tumor cells to fight lung cancer

by Bob Yirka , Medical XpressSchedule of LNT cells delivery of CRISPR-Cas9 nanoparticles for KRAS-mutant NSCLC treatment. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk8264A team o

Updated on: April 06,2024

Using cryo-shocked tumor cells to fight lung cancer

by Bob Yirka , Medical XpressSchedule of LNT cells delivery of CRISPR-Cas9 nanoparticles for KRAS-mutant NSCLC treatment. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk8264A team o

Updated on:April 06,2024

Study shows how morphine may contribute to bone loss and cancer-induced bone pain

by Stacy Pigott,University of ArizonaOn the left, cells isolated from breast cancer cells were treated with RANKL, a growth factor that stimulates bone resorption, to produce osteoclasts (pink).

Updated on: January 22,2024

Study shows how morphine may contribute to bone loss and cancer-induced bone pain

by Stacy Pigott,University of ArizonaOn the left, cells isolated from breast cancer cells were treated with RANKL, a growth factor that stimulates bone resorption, to produce osteoclasts (pink).

Updated on:January 22,2024

New hope for prostate cancer: New form of immunotherapy could prevent resistance to hormone therapy

byUniversity of SheffieldADT stimulates the PV accumulation of FR-β+ TAMs in mouse (Myc-CaP) and localized, human prostate tumors. Credit:Journal for ImmunoTherapy of Cancer(2024). D

Updated on: August 28,2024

New hope for prostate cancer: New form of immunotherapy could prevent resistance to hormone therapy

byUniversity of SheffieldADT stimulates the PV accumulation of FR-β+ TAMs in mouse (Myc-CaP) and localized, human prostate tumors. Credit:Journal for ImmunoTherapy of Cancer(2024). D

Updated on:August 28,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on: February 24,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on:February 24,2024

Researcher pioneers method of detecting early-stage cancer: Cheaper, faster, less invasive and accurate

by Dave Raney,University of CincinnatiJiajie Diao and his collaboratorare working with UC’s Technology Transfer team to commercialize their new method for early cancer diagnosis. Credit: C

Updated on: January 30,2024

Researcher pioneers method of detecting early-stage cancer: Cheaper, faster, less invasive and accurate

by Dave Raney,University of CincinnatiJiajie Diao and his collaboratorare working with UC’s Technology Transfer team to commercialize their new method for early cancer diagnosis. Credit: C

Updated on:January 30,2024

Mathematical modeling leads to a better understanding of prostate cancer

by Eva Schissler,University of CologneCredit:Cell Systems(2024). DOI: 10.1016/j.cels.2024.10.005A team led by Dr. Yuri Tolkach at the University of Cologne's Faculty of Medicine

Updated on: December 01,2024

Mathematical modeling leads to a better understanding of prostate cancer

by Eva Schissler,University of CologneCredit:Cell Systems(2024). DOI: 10.1016/j.cels.2024.10.005A team led by Dr. Yuri Tolkach at the University of Cologne's Faculty of Medicine

Updated on:December 01,2024

Researchers propose a navigation system to tackle medication supply bottlenecks

by Christoph Elhardt,ETH ZurichWholesalers can ease supply bottlenecks by rerouting remainder stocks of medications in short supply. Credit: ETH ZurichSupply bottlenecks for medications present

Updated on: May 06,2024

Researchers propose a navigation system to tackle medication supply bottlenecks

by Christoph Elhardt,ETH ZurichWholesalers can ease supply bottlenecks by rerouting remainder stocks of medications in short supply. Credit: ETH ZurichSupply bottlenecks for medications present

Updated on:May 06,2024

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone

Updated on: January 30,2024

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone

Updated on:January 30,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on: February 20,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on:February 20,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on: March 12,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on:March 12,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on: January 04,2024

Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on:January 04,2024