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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Team pioneers cancer treatment that targets bone metastases while sparing bone

Team pioneers cancer treatment that targets bone metastases while sparing bone

by University of California, IrvineCredit: CC0 Public DomainUniversity of California, Irvine researchers have developed and tested on mice a therapeutic treatment that uses engineered stem cells

Team pioneers cancer treatment that targets bone metastases while sparing bone

by University of California, IrvineCredit: CC0 Public DomainUniversity of California, Irvine researchers have developed and tested on mice a therapeutic treatment that uses engineered stem cells
Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu
Gene signature to tailor chemotherapy shows promise for improving breast cancer survival

Gene signature to tailor chemotherapy shows promise for improving breast cancer survival

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainUsing a gene signature technique to tailor chemotherapy for patients with early triple negative breast cancer shows promise as a way to

Gene signature to tailor chemotherapy shows promise for improving breast cancer survival

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainUsing a gene signature technique to tailor chemotherapy for patients with early triple negative breast cancer shows promise as a way to
New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body
Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi
Breast cancer may be likelier to spread to bone with nighttime dim-light exposure

Breast cancer may be likelier to spread to bone with nighttime dim-light exposure

by The Endocrine SocietyCredit: CC0 Public DomainExposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers

Breast cancer may be likelier to spread to bone with nighttime dim-light exposure

by The Endocrine SocietyCredit: CC0 Public DomainExposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers
New computer platform helps match patients with cancer to trials of targeted therapy

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are
Scientists find way to starve breast cancer cells

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme
A new combination therapy regimen shows promising results for prostate cancer

A new combination therapy regimen shows promising results for prostate cancer

by Huntsman Cancer InstituteCredit: CC0 Public DomainTALAPRO-2, a study led by Neeraj Agarwal, MD, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progress

A new combination therapy regimen shows promising results for prostate cancer

by Huntsman Cancer InstituteCredit: CC0 Public DomainTALAPRO-2, a study led by Neeraj Agarwal, MD, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progress
Tumor cells' response to chemotherapy is driven by randomness, shows study

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out
Study: More aggressive treatments needed to improve 5-year survival rate for glioblastoma

Study: More aggressive treatments needed to improve 5-year survival rate for glioblastoma

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicDespite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of

Study: More aggressive treatments needed to improve 5-year survival rate for glioblastoma

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicDespite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of
Immune evasion tactics of liver cancer cells revealed

Immune evasion tactics of liver cancer cells revealed

byeLifeActivated ß-catenin represses immune infiltration in liver cancer spheroids through exosomes. (a) Peripheral Blood Mononuclear Cells (PBMC) infiltration analysis protocol. Created with Bi

Immune evasion tactics of liver cancer cells revealed

byeLifeActivated ß-catenin represses immune infiltration in liver cancer spheroids through exosomes. (a) Peripheral Blood Mononuclear Cells (PBMC) infiltration analysis protocol. Created with Bi