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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Patients with metastatic colorectal cancer may continue benefiting from immunotherapy after treatment discontinuation

Patients with metastatic colorectal cancer may continue benefiting from immunotherapy after treatment discontinuation

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainThe majority of patients with metastatic colorectal cancer whose cancer did not progress during initial treatment with

Patients with metastatic colorectal cancer may continue benefiting from immunotherapy after treatment discontinuation

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainThe majority of patients with metastatic colorectal cancer whose cancer did not progress during initial treatment with
Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi
CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna
Novel AI method identifies locations, interactions among genes in and around tumors

Novel AI method identifies locations, interactions among genes in and around tumors

byJohns Hopkins University School of MedicineImage of a breast cancer tissue sample overlaid with visual representations of spatially interacting patterns of tumor and immune activity obtained t

Novel AI method identifies locations, interactions among genes in and around tumors

byJohns Hopkins University School of MedicineImage of a breast cancer tissue sample overlaid with visual representations of spatially interacting patterns of tumor and immune activity obtained t
Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d
Tracking radiation treatment in real time promises safer, more effective cancer therapy

Tracking radiation treatment in real time promises safer, more effective cancer therapy

by Jim Lynch,University of MichiganiRAI system schematic and the experimental setup. a, 3D schematic of the iRAI system for mapping the dose deposition in a patient during RT delivery. b, CAD vi

Tracking radiation treatment in real time promises safer, more effective cancer therapy

by Jim Lynch,University of MichiganiRAI system schematic and the experimental setup. a, 3D schematic of the iRAI system for mapping the dose deposition in a patient during RT delivery. b, CAD vi
Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone
Combining targeted therapy and immunotherapy improves overall survival in patients with anaplastic thyroid cancer

Combining targeted therapy and immunotherapy improves overall survival in patients with anaplastic thyroid cancer

byUniversity of Texas M. D. Anderson Cancer CenterOncoprint of targeted somatic gene variants of tumors in patients with anaplastic thyroid cancer (atc) enrolled in cohorts 1 to 3. Credit:

Combining targeted therapy and immunotherapy improves overall survival in patients with anaplastic thyroid cancer

byUniversity of Texas M. D. Anderson Cancer CenterOncoprint of targeted somatic gene variants of tumors in patients with anaplastic thyroid cancer (atc) enrolled in cohorts 1 to 3. Credit:
PSA levels after treatment may not be reliable predictor of survival for patients with prostate cancer

PSA levels after treatment may not be reliable predictor of survival for patients with prostate cancer

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led study has found treatments that reduce the risk of being diagnosed with a cancer recurrence based on rising pr

PSA levels after treatment may not be reliable predictor of survival for patients with prostate cancer

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led study has found treatments that reduce the risk of being diagnosed with a cancer recurrence based on rising pr
Boys should be given HPV jab, says vaccine committee

Boys should be given HPV jab, says vaccine committee

by Cancer Research UKHuman papillomavirus (HPV) vaccine. Credit:Wikimedia Commons/CC BY-SA 2.0It's nearly a decade since the human papillomavirus (HPV) vaccine was first introduced in t

Boys should be given HPV jab, says vaccine committee

by Cancer Research UKHuman papillomavirus (HPV) vaccine. Credit:Wikimedia Commons/CC BY-SA 2.0It's nearly a decade since the human papillomavirus (HPV) vaccine was first introduced in t
Study links gut microbiome and aggressive prostate cancer

Study links gut microbiome and aggressive prostate cancer

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, su

Study links gut microbiome and aggressive prostate cancer

by Cleveland ClinicCredit: CC0 Public DomainCleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, su
Right-sided colon cancer patients have poorer survival than those with left-sided disease

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv