Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on: July 05,2024

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on:July 05,2024

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on: January 04,2024

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on:January 04,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on: January 02,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on:January 02,2024

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated

Updated on: January 08,2024

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated

Updated on:January 08,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Findings suggest common salt activates anti-tumor cells

by Friederike Gawlik, Leibniz Institute for Natural Product Research and Infection BiologyImmune cells (purple and blue) attack tumor cells (red). Highly active CD8⁺ T cells treated with sodium chlori

Updated on: September 10,2024

Findings suggest common salt activates anti-tumor cells

by Friederike Gawlik, Leibniz Institute for Natural Product Research and Infection BiologyImmune cells (purple and blue) attack tumor cells (red). Highly active CD8⁺ T cells treated with sodium chlori

Updated on:September 10,2024

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu

Updated on: February 01,2024

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu

Updated on:February 01,2024

Aggressive cancer cells grow by protecting their identity, shows study

byRuhr-Universitaet-BochumGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112533For most types of cancer, the primary tumor is not the cause of death, but m

Updated on: January 22,2024

Aggressive cancer cells grow by protecting their identity, shows study

byRuhr-Universitaet-BochumGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112533For most types of cancer, the primary tumor is not the cause of death, but m

Updated on:January 22,2024

Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on: January 04,2024

Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on:January 04,2024

Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on: January 11,2024

Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on:January 11,2024

Novel urine-based test for non-invasive detection of bladder cancer

byUniversity of BirminghamCredit: designer 491A collaboration between University of Birmingham researchers and liquid biopsy cancer detection and screening company Nonacus, has resulted in a nov

Updated on: January 15,2024

Novel urine-based test for non-invasive detection of bladder cancer

byUniversity of BirminghamCredit: designer 491A collaboration between University of Birmingham researchers and liquid biopsy cancer detection and screening company Nonacus, has resulted in a nov

Updated on:January 15,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on: March 14,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on:March 14,2024