How colliding genetic processes drive aggressive cancers

byUniversity of Chicago Medical CenterLoss of CDK12 promotes large TD formation. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00848-4Cancer researchers at the University of Ch

Updated on: December 01,2024

How colliding genetic processes drive aggressive cancers

byUniversity of Chicago Medical CenterLoss of CDK12 promotes large TD formation. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00848-4Cancer researchers at the University of Ch

Updated on:December 01,2024

Study highlights promising drug combination for treating resistant breast cancer

by Lisa Marshall,University of Colorado at BoulderCredit:Cell(2023). DOI: 10.1016/j.cell.2023.05.013Cancer cells are even smarter than scientists previously believed, according to ne

Updated on: February 03,2024

Study highlights promising drug combination for treating resistant breast cancer

by Lisa Marshall,University of Colorado at BoulderCredit:Cell(2023). DOI: 10.1016/j.cell.2023.05.013Cancer cells are even smarter than scientists previously believed, according to ne

Updated on:February 03,2024

Pembrolizumab shows survival benefit for patients with renal cancer

by Elana GotkineFor patients with clear-cell renal cell carcinoma (ccRCC), overall survival (OS) is improved for those receiving pembrolizumab versus placebo at a median follow-up of about 57 months,

Updated on: May 11,2024

Pembrolizumab shows survival benefit for patients with renal cancer

by Elana GotkineFor patients with clear-cell renal cell carcinoma (ccRCC), overall survival (OS) is improved for those receiving pembrolizumab versus placebo at a median follow-up of about 57 months,

Updated on:May 11,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on: January 23,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on:January 23,2024

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

Updated on: January 21,2024

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

Updated on:January 21,2024

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated

Updated on: January 08,2024

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated

Updated on:January 08,2024

The surprising link between circadian disruption and cancer may have to do with temperature

byThe Scripps Research InstituteFor mice placed in ‘chronic jet lag’ (CJL) conditions, they showed a 68% increase in tumor burden when compared to mice placed in 12 hours of light, 12 hours of d

Updated on: January 21,2024

The surprising link between circadian disruption and cancer may have to do with temperature

byThe Scripps Research InstituteFor mice placed in ‘chronic jet lag’ (CJL) conditions, they showed a 68% increase in tumor burden when compared to mice placed in 12 hours of light, 12 hours of d

Updated on:January 21,2024

Researchers block two cancer cell signaling pathways and slow tumor growth

by Case Western Reserve UniversityBlocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma (EAC), the most common esophageal malignancy in t

Updated on: June 01,2024

Researchers block two cancer cell signaling pathways and slow tumor growth

by Case Western Reserve UniversityBlocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma (EAC), the most common esophageal malignancy in t

Updated on:June 01,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Team pioneers cancer treatment that targets bone metastases while sparing bone

by University of California, IrvineCredit: CC0 Public DomainUniversity of California, Irvine researchers have developed and tested on mice a therapeutic treatment that uses engineered stem cells

Updated on: May 27,2024

Team pioneers cancer treatment that targets bone metastases while sparing bone

by University of California, IrvineCredit: CC0 Public DomainUniversity of California, Irvine researchers have developed and tested on mice a therapeutic treatment that uses engineered stem cells

Updated on:May 27,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on: January 12,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on:January 12,2024

Largest study of its kind reveals adjuvant chemotherapy improves overall survival for pancreatic cancer patients

byCU Anschutz Medical CampusCredit: CC0 Public DomainToday, the University of Colorado Cancer Center released new research that showcases chemotherapy treatment before and after surgery for panc

Updated on: January 07,2024

Largest study of its kind reveals adjuvant chemotherapy improves overall survival for pancreatic cancer patients

byCU Anschutz Medical CampusCredit: CC0 Public DomainToday, the University of Colorado Cancer Center released new research that showcases chemotherapy treatment before and after surgery for panc

Updated on:January 07,2024