Using mice with humanized immune systems to test cancer immunotherapies

byKobe UniversityCurrently developed cancer immunotherapies modify the interaction of cancer cells and the immune system, making drug testing targeting human cancer outside of clinical trials di

Updated on: January 26,2024 13

Using mice with humanized immune systems to test cancer immunotherapies

byKobe UniversityCurrently developed cancer immunotherapies modify the interaction of cancer cells and the immune system, making drug testing targeting human cancer outside of clinical trials di

Updated on:January 26,2024 13

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on: February 20,2024 19

Researchers reveal role of PPDPF in development of mutant KRAS-driven pancreatic ductal adenocarcinoma

by Liu Jia,Chinese Academy of SciencesSchematic representation demonstrating the function of PPDPF in KRAS activation. Credit: Dr. XIE Dong's groupA recent study by Dr. Xie Dong's group

Updated on:February 20,2024 19

Potential markers identified for early detection and prevention of liver cancer

by FrontiersCredit: CC0 Public DomainLiver cancer is the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. Most cases are discovered too late for a cur

Updated on: March 09,2024 17

Potential markers identified for early detection and prevention of liver cancer

by FrontiersCredit: CC0 Public DomainLiver cancer is the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. Most cases are discovered too late for a cur

Updated on:March 09,2024 17

Future cancer treatment and fertility discussed in comprehensive review

by Karolinska InstitutetCredit:European Journal of Cancer(2024). DOI: 10.1016/j.ejca.2024.114010In recent years, the treatment landscape for solid tumors has undergone a notable chang

Updated on: March 20,2024 18

Future cancer treatment and fertility discussed in comprehensive review

by Karolinska InstitutetCredit:European Journal of Cancer(2024). DOI: 10.1016/j.ejca.2024.114010In recent years, the treatment landscape for solid tumors has undergone a notable chang

Updated on:March 20,2024 18

Discovery boosts the potential of new cancer-fighting drugs

by The Scripps Research InstituteCancer cell during cell division. Credit: National Institutes of HealthScientists at Scripps Research have uncovered a critical feature that a promising new class

Updated on: February 23,2024 19

Discovery boosts the potential of new cancer-fighting drugs

by The Scripps Research InstituteCancer cell during cell division. Credit: National Institutes of HealthScientists at Scripps Research have uncovered a critical feature that a promising new class

Updated on:February 23,2024 19

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on: January 12,2024 10

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on:January 12,2024 10

Delayed treatment effect predicting (DTEP) model found to enhance precision in immuno-oncology trial designs

by Science China PressAt the trial design stage, by inputting information on treatment stage, cancer type, and experimental and control arm regimens, investigators can utilize the nomogram or web

Updated on: March 30,2024 0

Delayed treatment effect predicting (DTEP) model found to enhance precision in immuno-oncology trial designs

by Science China PressAt the trial design stage, by inputting information on treatment stage, cancer type, and experimental and control arm regimens, investigators can utilize the nomogram or web

Updated on:March 30,2024 0

Cancer of the appendix: Very rare, but genes may play role

by Cara MurezWhile appendix cancer is rare, for a small percentage of patients the disease may be linked to a particular genetic variant, a new study suggests.Researchers built on earlier research wit

Updated on: December 28,2023 10

Cancer of the appendix: Very rare, but genes may play role

by Cara MurezWhile appendix cancer is rare, for a small percentage of patients the disease may be linked to a particular genetic variant, a new study suggests.Researchers built on earlier research wit

Updated on:December 28,2023 10

New tool pinpoints gaps in awareness of blood cancer symptoms

byUniversity of SurreySymptom awareness. *Cough was included as a non-blood cancer symptom. Credit:BMC Cancer(2023). DOI: 10.1186/s12885-023-11149-xA new tool could help identify gap

Updated on: January 13,2024 11

New tool pinpoints gaps in awareness of blood cancer symptoms

byUniversity of SurreySymptom awareness. *Cough was included as a non-blood cancer symptom. Credit:BMC Cancer(2023). DOI: 10.1186/s12885-023-11149-xA new tool could help identify gap

Updated on:January 13,2024 11

Research tests cost-effective approach to early-cancer detection from cell-free DNA in blood samples

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainEarly detection remains key to successfully treating many cancers, and early detection via cell-free DNA (cfDNA) circulati

Updated on: January 22,2024 11

Research tests cost-effective approach to early-cancer detection from cell-free DNA in blood samples

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainEarly detection remains key to successfully treating many cancers, and early detection via cell-free DNA (cfDNA) circulati

Updated on:January 22,2024 11

Drug combination shows promise in preclinical models of triple negative breast cancer

by Alhaji Janneh,Medical University of South CarolinaYueying Liu and Dr. Antonio Giordano study PLK1 inhibitors, traffic light-like signals that stop the uncontrolled growth of breast cancer cel

Updated on: May 23,2024 7

Drug combination shows promise in preclinical models of triple negative breast cancer

by Alhaji Janneh,Medical University of South CarolinaYueying Liu and Dr. Antonio Giordano study PLK1 inhibitors, traffic light-like signals that stop the uncontrolled growth of breast cancer cel

Updated on:May 23,2024 7

Study finds specific microbiome tied to long-term survival of patients with pancreatic cancer

by University of Texas M. D. Anderson Cancer CenterFlorencia McAllister, M.D. Credit: MD Anderson Cancer CenterA key difference between the few pancreatic cancer patients who survive long-term an

Updated on: July 04,2024 4

Study finds specific microbiome tied to long-term survival of patients with pancreatic cancer

by University of Texas M. D. Anderson Cancer CenterFlorencia McAllister, M.D. Credit: MD Anderson Cancer CenterA key difference between the few pancreatic cancer patients who survive long-term an

Updated on:July 04,2024 4