Scientists develop potential stealth cancer therapy

by Yale Cancer Center/Smilow Cancer HospitalCredit:ACS Central Science(2024). DOI: 10.1021/acscentsci.4c00559Sneaking by cancer's defenses, by disguising tumor-fighting antibodies insi

Updated on: July 17,2024

Scientists develop potential stealth cancer therapy

by Yale Cancer Center/Smilow Cancer HospitalCredit:ACS Central Science(2024). DOI: 10.1021/acscentsci.4c00559Sneaking by cancer's defenses, by disguising tumor-fighting antibodies insi

Updated on:July 17,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on: January 23,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on:January 23,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on: January 26,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on:January 26,2024

Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on: January 11,2024

Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on:January 11,2024

Breast cancer may be likelier to spread to bone with nighttime dim-light exposure

by The Endocrine SocietyCredit: CC0 Public DomainExposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers

Updated on: March 06,2024

Breast cancer may be likelier to spread to bone with nighttime dim-light exposure

by The Endocrine SocietyCredit: CC0 Public DomainExposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers

Updated on:March 06,2024

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on: January 12,2024

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on:January 12,2024

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme

Updated on: September 07,2024

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme

Updated on:September 07,2024

Study: More aggressive treatments needed to improve 5-year survival rate for glioblastoma

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicDespite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of

Updated on: May 27,2024

Study: More aggressive treatments needed to improve 5-year survival rate for glioblastoma

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicDespite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of

Updated on:May 27,2024

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu

Updated on: February 01,2024

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu

Updated on:February 01,2024

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body

Updated on: January 13,2024

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body

Updated on:January 13,2024

Immune evasion tactics of liver cancer cells revealed

byeLifeActivated ß-catenin represses immune infiltration in liver cancer spheroids through exosomes. (a) Peripheral Blood Mononuclear Cells (PBMC) infiltration analysis protocol. Created with Bi

Updated on: March 30,2024

Immune evasion tactics of liver cancer cells revealed

byeLifeActivated ß-catenin represses immune infiltration in liver cancer spheroids through exosomes. (a) Peripheral Blood Mononuclear Cells (PBMC) infiltration analysis protocol. Created with Bi

Updated on:March 30,2024

A new combination therapy regimen shows promising results for prostate cancer

by Huntsman Cancer InstituteCredit: CC0 Public DomainTALAPRO-2, a study led by Neeraj Agarwal, MD, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progress

Updated on: January 28,2024

A new combination therapy regimen shows promising results for prostate cancer

by Huntsman Cancer InstituteCredit: CC0 Public DomainTALAPRO-2, a study led by Neeraj Agarwal, MD, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progress

Updated on:January 28,2024