Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on: January 07,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on:January 07,2024

New study identifies ganoderic acid DM as potential treatment for breast cancer

byChinese Academy of SciencesProtein-protein interaction network of the 53 potential targets for treating breast cancer. Credit: Mohammed Sharif SwallahBreast cancer is one of the most common ca

Updated on: October 22,2024

New study identifies ganoderic acid DM as potential treatment for breast cancer

byChinese Academy of SciencesProtein-protein interaction network of the 53 potential targets for treating breast cancer. Credit: Mohammed Sharif SwallahBreast cancer is one of the most common ca

Updated on:October 22,2024

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on: January 12,2024

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on:January 12,2024

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme

Updated on: September 07,2024

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme

Updated on:September 07,2024

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu

Updated on: February 01,2024

Study: Risk of cancer remains high for women over 50 with genetic BRCA1 or BRCA2 mutation

by University of TorontoCredit: Pixabay/CC0 Public DomainAlthough genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mu

Updated on:February 01,2024

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body

Updated on: January 13,2024

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body

Updated on:January 13,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on: January 23,2024

Tumor cells' response to chemotherapy is driven by randomness, shows study

byGarvan Institute of Medical ResearchNeuroblastoma cells (cyan) growing as a tumour and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out

Updated on:January 23,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on: January 26,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on:January 26,2024

Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on: January 11,2024

Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on:January 11,2024

Breast cancer may be likelier to spread to bone with nighttime dim-light exposure

by The Endocrine SocietyCredit: CC0 Public DomainExposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers

Updated on: March 06,2024

Breast cancer may be likelier to spread to bone with nighttime dim-light exposure

by The Endocrine SocietyCredit: CC0 Public DomainExposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers

Updated on:March 06,2024

Study: More aggressive treatments needed to improve 5-year survival rate for glioblastoma

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicDespite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of

Updated on: May 27,2024

Study: More aggressive treatments needed to improve 5-year survival rate for glioblastoma

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicDespite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of

Updated on:May 27,2024

Swallowable device to detect Barrett's esophagus receives FDA 510(k) clearance

by Case Western Reserve University"FDA clearance of the EsoCheck device means the device is now available to patients and physicians as a non-endoscopic method for sampling the esophagus. Th

Updated on: May 09,2024

Swallowable device to detect Barrett's esophagus receives FDA 510(k) clearance

by Case Western Reserve University"FDA clearance of the EsoCheck device means the device is now available to patients and physicians as a non-endoscopic method for sampling the esophagus. Th

Updated on:May 09,2024