Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on: January 04,2024

Renal impairment linked to worse prognosis in IgD multiple myeloma

by Elana GotkineFor patients with immunoglobulin D multiple myeloma (IgD MM), those with renal impairment (RI) have poorer prognosis and shorter median survival than those with no renal impairment (no

Updated on:January 04,2024

Liver cancer deaths climb by around 50% in the last decade

by Cancer Research UKA graph showing liver cancer mortality. Credit: Cancer Research UKLiver cancer deaths have increased by around 50% in the last decade and have tripled since records began, ac

Updated on: April 23,2024

Liver cancer deaths climb by around 50% in the last decade

by Cancer Research UKA graph showing liver cancer mortality. Credit: Cancer Research UKLiver cancer deaths have increased by around 50% in the last decade and have tripled since records began, ac

Updated on:April 23,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on: February 24,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on:February 24,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on: January 12,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on:January 12,2024

Researcher pioneers method of detecting early-stage cancer: Cheaper, faster, less invasive and accurate

by Dave Raney,University of CincinnatiJiajie Diao and his collaboratorare working with UC’s Technology Transfer team to commercialize their new method for early cancer diagnosis. Credit: C

Updated on: January 30,2024

Researcher pioneers method of detecting early-stage cancer: Cheaper, faster, less invasive and accurate

by Dave Raney,University of CincinnatiJiajie Diao and his collaboratorare working with UC’s Technology Transfer team to commercialize their new method for early cancer diagnosis. Credit: C

Updated on:January 30,2024

Secret vulnerabilities of cancer's 'Death Star' protein revealed

byCenter for Genomic RegulationA three-dimensional image showing the human protein KRAS (blue) interacting with RAF1 (yellow), one of its main partners. The blue-to-red colour gradient indicates

Updated on: December 30,2023

Secret vulnerabilities of cancer's 'Death Star' protein revealed

byCenter for Genomic RegulationA three-dimensional image showing the human protein KRAS (blue) interacting with RAF1 (yellow), one of its main partners. The blue-to-red colour gradient indicates

Updated on:December 30,2023

How conquering a rare leukemia in children revolutionized cancer care for millions

by Marie McculloughFifty years ago, children with an aggressive form of leukemia went from diagnosis to death in a few months, as the disease rampaged through their lymph nodes, spleens, livers, and n

Updated on: March 01,2024

How conquering a rare leukemia in children revolutionized cancer care for millions

by Marie McculloughFifty years ago, children with an aggressive form of leukemia went from diagnosis to death in a few months, as the disease rampaged through their lymph nodes, spleens, livers, and n

Updated on:March 01,2024

Circular RNAs—the new frontier in cancer research

byFlinders UniversityCircular RNA biogenesis and how they are dysregulated in cancer. Credit:Nature Reviews Cancer(2024). DOI: 10.1038/s41568-024-00721-7Unraveling the complexities o

Updated on: August 27,2024

Circular RNAs—the new frontier in cancer research

byFlinders UniversityCircular RNA biogenesis and how they are dysregulated in cancer. Credit:Nature Reviews Cancer(2024). DOI: 10.1038/s41568-024-00721-7Unraveling the complexities o

Updated on:August 27,2024

Overcoming the limits of immunotherapies

byUniversity of WürzburgKarl Petri (left) is setting up an Emmy Noether research group at the University Hospital of Würzburg with the support of the German Research Foundation. Alexandre Truber

Updated on: August 27,2024

Overcoming the limits of immunotherapies

byUniversity of WürzburgKarl Petri (left) is setting up an Emmy Noether research group at the University Hospital of Würzburg with the support of the German Research Foundation. Alexandre Truber

Updated on:August 27,2024

Study shows how morphine may contribute to bone loss and cancer-induced bone pain

by Stacy Pigott,University of ArizonaOn the left, cells isolated from breast cancer cells were treated with RANKL, a growth factor that stimulates bone resorption, to produce osteoclasts (pink).

Updated on: January 22,2024

Study shows how morphine may contribute to bone loss and cancer-induced bone pain

by Stacy Pigott,University of ArizonaOn the left, cells isolated from breast cancer cells were treated with RANKL, a growth factor that stimulates bone resorption, to produce osteoclasts (pink).

Updated on:January 22,2024

Creating a 'parts list' for cancer's spread, with help from a worm

by Duke UniversityA tiny worm cell breaking through the wall that normally holds cells in place. Credit:Development(2023). DOI: 10.1242/dev.201570What makes some cancer cells stay put

Updated on: January 30,2024

Creating a 'parts list' for cancer's spread, with help from a worm

by Duke UniversityA tiny worm cell breaking through the wall that normally holds cells in place. Credit:Development(2023). DOI: 10.1242/dev.201570What makes some cancer cells stay put

Updated on:January 30,2024