Clues found regarding tumor suppressor gene's breast cancer activity

byJohns Hopkins University School of MedicineCredit: Saraswati Sukumar and Priya PaiResearchers at the Johns Hopkins Kimmel Cancer Center have revealed how the gene HOXA5 may work to suppress fo

Updated on: January 21,2024

Clues found regarding tumor suppressor gene's breast cancer activity

byJohns Hopkins University School of MedicineCredit: Saraswati Sukumar and Priya PaiResearchers at the Johns Hopkins Kimmel Cancer Center have revealed how the gene HOXA5 may work to suppress fo

Updated on:January 21,2024

Shining light on rare nerve tumors illuminates a fresh path for fighting cancer

by Cincinnati Children's Hospital Medical CenterNew findings published inScience Signalingsuggest that targeting mechanical signals between cells may become a fresh approach to fi

Updated on: April 23,2024

Shining light on rare nerve tumors illuminates a fresh path for fighting cancer

by Cincinnati Children's Hospital Medical CenterNew findings published inScience Signalingsuggest that targeting mechanical signals between cells may become a fresh approach to fi

Updated on:April 23,2024

Simulating your cancer treatment on a computer

by University of OsloArnoldo Frigessi is the main person behind the new idea of making tens of thousands of virtual copies of the individual cancer patient and then testing all the treatments in

Updated on: April 23,2024

Simulating your cancer treatment on a computer

by University of OsloArnoldo Frigessi is the main person behind the new idea of making tens of thousands of virtual copies of the individual cancer patient and then testing all the treatments in

Updated on:April 23,2024

Using cryo-shocked tumor cells to fight lung cancer

by Bob Yirka , Medical XpressSchedule of LNT cells delivery of CRISPR-Cas9 nanoparticles for KRAS-mutant NSCLC treatment. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk8264A team o

Updated on: April 06,2024

Using cryo-shocked tumor cells to fight lung cancer

by Bob Yirka , Medical XpressSchedule of LNT cells delivery of CRISPR-Cas9 nanoparticles for KRAS-mutant NSCLC treatment. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adk8264A team o

Updated on:April 06,2024

Study shows elevated cancer risk for women with endometriosis

byHuntsman Cancer InstituteCredit: CC0 Public DomainA landmark study from researchers at Huntsman Cancer Institute at the University of Utah (the U), the Spencer Fox Eccles School of Medicine at

Updated on: August 03,2024

Study shows elevated cancer risk for women with endometriosis

byHuntsman Cancer InstituteCredit: CC0 Public DomainA landmark study from researchers at Huntsman Cancer Institute at the University of Utah (the U), the Spencer Fox Eccles School of Medicine at

Updated on:August 03,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Researchers identify the mutations that drive resistance to PI3K inhibitors in breast cancer, find they can be overcome

by Mass General BrighamSecondary mutations in the PI3K/AKT pathway emerge during treatment with inavolisib and lead to acquired resistance. A-B, Droplet digital PCR analysis of serial ctDNA sampl

Updated on: June 24,2024

Researchers identify the mutations that drive resistance to PI3K inhibitors in breast cancer, find they can be overcome

by Mass General BrighamSecondary mutations in the PI3K/AKT pathway emerge during treatment with inavolisib and lead to acquired resistance. A-B, Droplet digital PCR analysis of serial ctDNA sampl

Updated on:June 24,2024

Cancer hijacks the microbiome to glut itself on glucose

by Garth Sundem,CU Anschutz Medical CampusHaobin Ye, PhD. Credit: CU Anschutz Medical CampusCancer needs energy to drive its out-of-control growth. It gets energy in the form of glucose, in fact

Updated on: March 06,2024

Cancer hijacks the microbiome to glut itself on glucose

by Garth Sundem,CU Anschutz Medical CampusHaobin Ye, PhD. Credit: CU Anschutz Medical CampusCancer needs energy to drive its out-of-control growth. It gets energy in the form of glucose, in fact

Updated on:March 06,2024

Trial finds that adagrasib demonstrates durable clinical activity in patients with KRAS-G12C mutations

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe oral, selective KRAS G12C inhibitor KRAS-G12C inhibitor adagrasib demonstrated durable clinical activity,

Updated on: January 04,2024

Trial finds that adagrasib demonstrates durable clinical activity in patients with KRAS-G12C mutations

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe oral, selective KRAS G12C inhibitor KRAS-G12C inhibitor adagrasib demonstrated durable clinical activity,

Updated on:January 04,2024

Deadly form of advanced prostate cancer is common, calls for distinct treatment

by University of California, San FranciscoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0A new study of prostate

Updated on: April 09,2024

Deadly form of advanced prostate cancer is common, calls for distinct treatment

by University of California, San FranciscoMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0A new study of prostate

Updated on:April 09,2024

Extending chemo slashes risk of aggressive childhood leukemia coming back

by Princess Máxima Center for Pediatric OncologyCredit: CC0 Public DomainMany children with acute lymphoblastic leukemia (ALL) have a good outcome of their disease. After two years of chemotherapy tre

Updated on: January 16,2024

Extending chemo slashes risk of aggressive childhood leukemia coming back

by Princess Máxima Center for Pediatric OncologyCredit: CC0 Public DomainMany children with acute lymphoblastic leukemia (ALL) have a good outcome of their disease. After two years of chemotherapy tre

Updated on:January 16,2024

Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell

Updated on: January 21,2024

Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell

Updated on:January 21,2024