Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered

Updated on: December 19,2023 15

Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered

Updated on:December 19,2023 15

Scientists identify gene target to boost effectiveness of cancer immunotherapy

by Katie Marquedant,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainImmune checkpoint inhibitors are important medications that boost the immune system's response against vari

Updated on: December 27,2023 9

Scientists identify gene target to boost effectiveness of cancer immunotherapy

by Katie Marquedant,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainImmune checkpoint inhibitors are important medications that boost the immune system's response against vari

Updated on:December 27,2023 9

DetermaIO Assay Helps Inform Benefit With Single-Agent Immunotherapy in Advanced NSCLC

November 22, 2022Caroline SeymourThe score of the 27-gene Determa immune-oncology assay demonstrated a correlation with overall survival and progression-free survival in patients with advanced non–sma

Updated on: October 17,2023 34

DetermaIO Assay Helps Inform Benefit With Single-Agent Immunotherapy in Advanced NSCLC

November 22, 2022Caroline SeymourThe score of the 27-gene Determa immune-oncology assay demonstrated a correlation with overall survival and progression-free survival in patients with advanced non–sma

Updated on:October 17,2023 34

Oncolytic Virus Enables the Immune System to Attack Tumors

by Shana SpindlerOne of the most important findings in cancer research in the past two decades is that tumors can create force field-like protection against the immune system. A new study has identifi

Updated on: October 15,2023 291

Oncolytic Virus Enables the Immune System to Attack Tumors

by Shana SpindlerOne of the most important findings in cancer research in the past two decades is that tumors can create force field-like protection against the immune system. A new study has identifi

Updated on:October 15,2023 291

Scientists map genetic evolution of chronic lymphocytic leukemia to Richter's syndrome

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainEvery year, up to 1% of patients with chronic lymphocytic leukemia (CLL), a slow-growing blood cancer, have their disease transform

Updated on: December 27,2023 9

Scientists map genetic evolution of chronic lymphocytic leukemia to Richter's syndrome

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainEvery year, up to 1% of patients with chronic lymphocytic leukemia (CLL), a slow-growing blood cancer, have their disease transform

Updated on:December 27,2023 9

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,

Updated on: December 21,2023 10

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,

Updated on:December 21,2023 10

Larotrectinib in tumours with NTRK gene fusion: Data are not yet sufficient

byInstitute for Quality and Efficiency in Health CareCredit: Institute for Quality and Efficiency in Health CareIn the summer of 2019, larotrectinib was approved as the first drug in Europe to b

Updated on: December 20,2023 19

Larotrectinib in tumours with NTRK gene fusion: Data are not yet sufficient

byInstitute for Quality and Efficiency in Health CareCredit: Institute for Quality and Efficiency in Health CareIn the summer of 2019, larotrectinib was approved as the first drug in Europe to b

Updated on:December 20,2023 19

Proton therapy lowers risk of side effects in cancer compared to traditional radiation

byPerelman School of Medicine at the University of PennsylvaniaStudy finds protons led to two-thirds reduction in unplanned hospitalizations. Credit: Penn MedicineProton therapy leads to signifi

Updated on: December 20,2023 19

Proton therapy lowers risk of side effects in cancer compared to traditional radiation

byPerelman School of Medicine at the University of PennsylvaniaStudy finds protons led to two-thirds reduction in unplanned hospitalizations. Credit: Penn MedicineProton therapy leads to signifi

Updated on:December 20,2023 19

Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainPatients with cancers that are driven by certain mutations occurring in response to DNA damage can be safe

Updated on: December 19,2023 10

Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainPatients with cancers that are driven by certain mutations occurring in response to DNA damage can be safe

Updated on:December 19,2023 10

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on: December 18,2023 22

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on:December 18,2023 22

WHO moves step closer to cheaper breast cancer treatment

The World Health Organization has approved a biosimilar version of Trastuzumab—the drug used to treat breast cancer—that is generally 65 percent cheaper than the originalThe World Health Organization

Updated on: December 22,2023 16

WHO moves step closer to cheaper breast cancer treatment

The World Health Organization has approved a biosimilar version of Trastuzumab—the drug used to treat breast cancer—that is generally 65 percent cheaper than the originalThe World Health Organization

Updated on:December 22,2023 16

Targeted therapy drug helps women with aggressive breast cancer live longer

by Denise Heady,University of California, Los AngelesSenior author Dr. Dennis Slamon says “there is absolutely no reason to wait” to give women treatment that combines ribociclib with hormone th

Updated on: December 22,2023 10

Targeted therapy drug helps women with aggressive breast cancer live longer

by Denise Heady,University of California, Los AngelesSenior author Dr. Dennis Slamon says “there is absolutely no reason to wait” to give women treatment that combines ribociclib with hormone th

Updated on:December 22,2023 10