Arf1 inhibitors promote the infiltration of cytotoxic T lymphocytes into tumors by affecting lipid metabolism

by Higher Education PressScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have b

Updated on: March 30,2024 16

Arf1 inhibitors promote the infiltration of cytotoxic T lymphocytes into tumors by affecting lipid metabolism

by Higher Education PressScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have b

Updated on:March 30,2024 16

Study reveals dual role of protein in cancer treatment

by Denise Heady,University of California, Los AngelesGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114289Investigators at the UCLA Health Jonsson Comprehe

Updated on: July 17,2024 0

Study reveals dual role of protein in cancer treatment

by Denise Heady,University of California, Los AngelesGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114289Investigators at the UCLA Health Jonsson Comprehe

Updated on:July 17,2024 0

Dietary change starves cancer cells, overcoming treatment resistance

by University of MichiganGreen staining shows mTORC1 is significantly increased due to disruption in GATOR1 in a mouse model of colon cancer. Credit: Sumeet SolankiA dietary change could be a key

Updated on: February 23,2024 13

Dietary change starves cancer cells, overcoming treatment resistance

by University of MichiganGreen staining shows mTORC1 is significantly increased due to disruption in GATOR1 in a mouse model of colon cancer. Credit: Sumeet SolankiA dietary change could be a key

Updated on:February 23,2024 13

Team identifies how certain immune cells contribute to worse survival rates in HER2-positive breast cancer patients

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainPatients with a type of breast cancer called HER2-positive are less likely to survive if their initial tr

Updated on: February 24,2024 12

Team identifies how certain immune cells contribute to worse survival rates in HER2-positive breast cancer patients

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainPatients with a type of breast cancer called HER2-positive are less likely to survive if their initial tr

Updated on:February 24,2024 12

Research shows novel drug pairing could beat pancreatic cancer

byUniversity of California - San DiegoMouse pancreatic tumors were significantly smaller after being treated with a combination of KRAS inhibitor MRTX1133 and ERBB inhibitor Afatinib (bottom row

Updated on: January 16,2024 16

Research shows novel drug pairing could beat pancreatic cancer

byUniversity of California - San DiegoMouse pancreatic tumors were significantly smaller after being treated with a combination of KRAS inhibitor MRTX1133 and ERBB inhibitor Afatinib (bottom row

Updated on:January 16,2024 16

Number of cancer treatments provided decreased in first year of COVID-19

by Elana GotkineIn the first year of the pandemic, there was a significant decrease in the number of cancer treatments provided, resulting from a decrease in the number of cancer diagnoses, according

Updated on: May 05,2024 19

Number of cancer treatments provided decreased in first year of COVID-19

by Elana GotkineIn the first year of the pandemic, there was a significant decrease in the number of cancer treatments provided, resulting from a decrease in the number of cancer diagnoses, according

Updated on:May 05,2024 19

Night work may increase the risk of aggressive prostate cancer in offshore petroleum workers

by University of Oslo, Faculty of MedicineExposure-risk curve for a non-linear model of rollover shift work exposure, generated using restricted cubic splines with five knots (0.58, 3.82, 8.99, 14.98

Updated on: January 29,2024 15

Night work may increase the risk of aggressive prostate cancer in offshore petroleum workers

by University of Oslo, Faculty of MedicineExposure-risk curve for a non-linear model of rollover shift work exposure, generated using restricted cubic splines with five knots (0.58, 3.82, 8.99, 14.98

Updated on:January 29,2024 15

CAR T cell therapy may eliminate tumor cells missed by surgery

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainCAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood canc

Updated on: April 09,2024 16

CAR T cell therapy may eliminate tumor cells missed by surgery

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainCAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood canc

Updated on:April 09,2024 16

Researchers describe a new resistance mechanism

by IDIBELL-Bellvitge Biomedical Research InstituteDue to the treatment with the antibody against Semaphorin 4D (anti-Sema4D), changes occur in the tumor vasculature as well as a decrease in tumor

Updated on: June 08,2024 4

Researchers describe a new resistance mechanism

by IDIBELL-Bellvitge Biomedical Research InstituteDue to the treatment with the antibody against Semaphorin 4D (anti-Sema4D), changes occur in the tumor vasculature as well as a decrease in tumor

Updated on:June 08,2024 4

Researchers learn how cancer cells divide despite treatment

by Kendall Daniels,University of North Carolina at Chapel Hill School of MedicineResearchers first saw evidence that some cells were escaping arrest in the continued presence of Palbociclib just

Updated on: August 03,2024 0

Researchers learn how cancer cells divide despite treatment

by Kendall Daniels,University of North Carolina at Chapel Hill School of MedicineResearchers first saw evidence that some cells were escaping arrest in the continued presence of Palbociclib just

Updated on:August 03,2024 0

Redefining colorectal cancer subtypes

by The City University of New YorkCredit: The City University of New YorkThere is a long-standing belief that colorectal cancer (CRC), which causes some 50,000 deaths in the United States each ye

Updated on: April 07,2024 11

Redefining colorectal cancer subtypes

by The City University of New YorkCredit: The City University of New YorkThere is a long-standing belief that colorectal cancer (CRC), which causes some 50,000 deaths in the United States each ye

Updated on:April 07,2024 11

Engineered T cells may be harnessed to kill solid tumor cells

by Tel Aviv UniversityCredit: Tel Aviv UniversityThere is now a multitude of therapies to treat cancer, from chemotherapy and radiation to immunotherapy and small molecule inhibitors. Chemotherap

Updated on: March 01,2024 13

Engineered T cells may be harnessed to kill solid tumor cells

by Tel Aviv UniversityCredit: Tel Aviv UniversityThere is now a multitude of therapies to treat cancer, from chemotherapy and radiation to immunotherapy and small molecule inhibitors. Chemotherap

Updated on:March 01,2024 13