Research finds alternating estrogen and anti-estrogen therapies effective in treating metastatic breast cancer

by Dartmouth HealthCredit: Unsplash/CC0 Public DomainAdvanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor. However

Updated on: February 24,2024 14

Research finds alternating estrogen and anti-estrogen therapies effective in treating metastatic breast cancer

by Dartmouth HealthCredit: Unsplash/CC0 Public DomainAdvanced or metastatic estrogen receptor-positive (ER+) breast cancer is commonly treated with drugs that block the estrogen receptor. However

Updated on:February 24,2024 14

Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50%

by SWOG Cancer Research NetworkCredit: CC0 Public DomainIn exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major patholog

Updated on: April 22,2024 20

Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50%

by SWOG Cancer Research NetworkCredit: CC0 Public DomainIn exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major patholog

Updated on:April 22,2024 20

Is assisted dying available equally to all in New Zealand?

by Jessica Young, Aida Dehkhoda and Jeanne Snelling,The ConversationCredit: Pixabay/CC0 Public DomainJust over two years ago, terminally ill New Zealanders were given the right to request a medi

Updated on: April 22,2024 15

Is assisted dying available equally to all in New Zealand?

by Jessica Young, Aida Dehkhoda and Jeanne Snelling,The ConversationCredit: Pixabay/CC0 Public DomainJust over two years ago, terminally ill New Zealanders were given the right to request a medi

Updated on:April 22,2024 15

The X chromosome is silenced in some male cancers

by Cell PressGraphical abstract depicting the study’s workflow. Credit:Cell Systems/Sadagopan et al.Cancer cells acquire genetic anomalies that allow them to grow and proliferate unchecked.

Updated on: February 03,2024 12

The X chromosome is silenced in some male cancers

by Cell PressGraphical abstract depicting the study’s workflow. Credit:Cell Systems/Sadagopan et al.Cancer cells acquire genetic anomalies that allow them to grow and proliferate unchecked.

Updated on:February 03,2024 12

Oncogenic driver FGFR3-TACC3 requires 5 coiled-coil heptads for activation and disulfide bonds for stability

by Impact Journals LLCFGFR3-TACC3 fusion proteins. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28359FGFR3-TACC3 represents an oncogenic fusion protein frequently identified in gliobl

Updated on: January 30,2024 10

Oncogenic driver FGFR3-TACC3 requires 5 coiled-coil heptads for activation and disulfide bonds for stability

by Impact Journals LLCFGFR3-TACC3 fusion proteins. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28359FGFR3-TACC3 represents an oncogenic fusion protein frequently identified in gliobl

Updated on:January 30,2024 10

Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar

Updated on: January 07,2024 9

Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar

Updated on:January 07,2024 9

Researchers discover how to steer army of immune cells toward cancer

by University of Rochester Medical CenterhHER2 CAR-T cell assays and in vivo distribution. a. Gating strategy for detection of hHER2-CAR-T cells. A median of > 90% of mouse CD8 T cells transdu

Updated on: February 01,2024 19

Researchers discover how to steer army of immune cells toward cancer

by University of Rochester Medical CenterhHER2 CAR-T cell assays and in vivo distribution. a. Gating strategy for detection of hHER2-CAR-T cells. A median of > 90% of mouse CD8 T cells transdu

Updated on:February 01,2024 19

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a

Updated on: January 23,2024 18

More cancers are diagnosed at an advanced stage if patients already have type 2 diabetes, study finds

by European Organisation for Research and Treatment of CancerCredit: CC0 Public DomainA study of 11,945 people in six European countries has shown that people with type 2 diabetes who develop cancer a

Updated on:January 23,2024 18

New study flips the script on liver cancer

by University of California - San DiegoUC San Diego scientists find the protein ATF4 prevents liver damage and its progression to cancer by blocking ferroptosis, an iron-dependent form of liver c

Updated on: February 18,2024 13

New study flips the script on liver cancer

by University of California - San DiegoUC San Diego scientists find the protein ATF4 prevents liver damage and its progression to cancer by blocking ferroptosis, an iron-dependent form of liver c

Updated on:February 18,2024 13

Why alarm is easing over a rise in pancreatic cancer among the young

by Robin FosterExperts have been concerned by rising rates of pancreatic cancer in young adults, but new research reveals the jump in cases has not been accompanied by any increase in deaths from the

Updated on: December 02,2024 0

Why alarm is easing over a rise in pancreatic cancer among the young

by Robin FosterExperts have been concerned by rising rates of pancreatic cancer in young adults, but new research reveals the jump in cases has not been accompanied by any increase in deaths from the

Updated on:December 02,2024 0

Researchers pinpoint potential treatment for lethal childhood cancer

by McMaster UniversityCredit: Unsplash/CC0 Public DomainAn enzyme that drives the growth of an often-lethal childhood brain cancer may hold the key to a future treatment, says a McMaster Universi

Updated on: February 01,2024 16

Researchers pinpoint potential treatment for lethal childhood cancer

by McMaster UniversityCredit: Unsplash/CC0 Public DomainAn enzyme that drives the growth of an often-lethal childhood brain cancer may hold the key to a future treatment, says a McMaster Universi

Updated on:February 01,2024 16

Treatment found to reduce progression of rare blood cancer by 74%

Credit: Wikimedia CommonsA treatment that involves genetically modifying the body's own immune cells has been found to cut the risk of disease progression by 74 percent in people with a rare type

Updated on: January 29,2024 11

Treatment found to reduce progression of rare blood cancer by 74%

Credit: Wikimedia CommonsA treatment that involves genetically modifying the body's own immune cells has been found to cut the risk of disease progression by 74 percent in people with a rare type

Updated on:January 29,2024 11