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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Research reveals potential targets for therapeutic development for glioblastoma

Research reveals potential targets for therapeutic development for glioblastoma

by Amy Richardson,University of Alabama at BirminghamGraphical abstract. Credit:JCI Insight(2022). DOI: 10.1172/jci.insight.148717The University of Alabama at Birmingham Marnix E. He

Research reveals potential targets for therapeutic development for glioblastoma

by Amy Richardson,University of Alabama at BirminghamGraphical abstract. Credit:JCI Insight(2022). DOI: 10.1172/jci.insight.148717The University of Alabama at Birmingham Marnix E. He
Researchers find an epigenetic key that unlocks common deadly cancers

Researchers find an epigenetic key that unlocks common deadly cancers

by Katherine Fenz,Rockefeller UniversityLesions (in green) akin to basal cell carcinoma that were induced by SOX9 in the epidermis. Abnormal differentiation is shown in red, and blue marks cell

Researchers find an epigenetic key that unlocks common deadly cancers

by Katherine Fenz,Rockefeller UniversityLesions (in green) akin to basal cell carcinoma that were induced by SOX9 in the epidermis. Abnormal differentiation is shown in red, and blue marks cell
Study shows combining AI models improves breast cancer risk assessment

Study shows combining AI models improves breast cancer risk assessment

byRadiological Society of North AmericaFull-field digital mammograms (right mediolateral oblique view) in a 59-year-old woman show (A) the screening mammogram obtained during the study period an

Study shows combining AI models improves breast cancer risk assessment

byRadiological Society of North AmericaFull-field digital mammograms (right mediolateral oblique view) in a 59-year-old woman show (A) the screening mammogram obtained during the study period an
Cell competition may explain cancer relapses, research suggests

Cell competition may explain cancer relapses, research suggests

byUT Southwestern Medical CenterCredit:Cancer Discovery(2022). DOI: 10.1158/2159-8290.CD-22-0236A normal process called cell competition, in which healthy tissues eliminate unhealthy

Cell competition may explain cancer relapses, research suggests

byUT Southwestern Medical CenterCredit:Cancer Discovery(2022). DOI: 10.1158/2159-8290.CD-22-0236A normal process called cell competition, in which healthy tissues eliminate unhealthy
Researchers discover iron-targeting approaches to halt proliferation of cancer cells

Researchers discover iron-targeting approaches to halt proliferation of cancer cells

by University of Arizona(From left) Yu-Shien Sung, doctoral student in the Tomat Lab, and University of Arizona Cancer Center member Elisa Tomat, PhD, are studying an iron-targeting molecule that

Researchers discover iron-targeting approaches to halt proliferation of cancer cells

by University of Arizona(From left) Yu-Shien Sung, doctoral student in the Tomat Lab, and University of Arizona Cancer Center member Elisa Tomat, PhD, are studying an iron-targeting molecule that
Characterization of mutational 'coldspots' in the cancer genome

Characterization of mutational 'coldspots' in the cancer genome

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Pixabay/CC0 Public DomainMutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organi

Characterization of mutational 'coldspots' in the cancer genome

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Pixabay/CC0 Public DomainMutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organi
Biochemists, cancer biologists find key vulnerability in rare brain tumors

Biochemists, cancer biologists find key vulnerability in rare brain tumors

by Anne Manning,Colorado State UniversityCredit: Pixabay/CC0 Public DomainSince the start of her career, Jennifer DeLuca has been fascinated by mitosis, the everyday biological process of cell d

Biochemists, cancer biologists find key vulnerability in rare brain tumors

by Anne Manning,Colorado State UniversityCredit: Pixabay/CC0 Public DomainSince the start of her career, Jennifer DeLuca has been fascinated by mitosis, the everyday biological process of cell d
Artificial intelligence analysis of DNA fragmentomes and protein biomarkers noninvasively detects ovarian cancer

Artificial intelligence analysis of DNA fragmentomes and protein biomarkers noninvasively detects ovarian cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA blood-based machine learning assay that combines cell-free DNA (cfDNA) fragment patterns and levels of the proteins

Artificial intelligence analysis of DNA fragmentomes and protein biomarkers noninvasively detects ovarian cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA blood-based machine learning assay that combines cell-free DNA (cfDNA) fragment patterns and levels of the proteins
Beating by overheating: A new strategy to combat cancer

Beating by overheating: A new strategy to combat cancer

byNetherlands Cancer InstituteOne could compare cancer cells subjected to the paradoxial approach in this study to the engine of a racing car: if you crank up the RPM and then turn off the cooli

Beating by overheating: A new strategy to combat cancer

byNetherlands Cancer InstituteOne could compare cancer cells subjected to the paradoxial approach in this study to the engine of a racing car: if you crank up the RPM and then turn off the cooli
How pancreatic cancer defies treatment by leveraging a protein

How pancreatic cancer defies treatment by leveraging a protein

by University of California - San DiegoPancreatic cancer cells (nuclei in blue) are shown growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cancer is the

How pancreatic cancer defies treatment by leveraging a protein

by University of California - San DiegoPancreatic cancer cells (nuclei in blue) are shown growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cancer is the
Understanding the maturation of white blood cells to find new therapies against lymphoblastic leukemia

Understanding the maturation of white blood cells to find new therapies against lymphoblastic leukemia

byJosep Carreras Leukaemia Research InstitutePax5 K198 acetylation regulates gene expression. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01995-7More than 400 people, 80%

Understanding the maturation of white blood cells to find new therapies against lymphoblastic leukemia

byJosep Carreras Leukaemia Research InstitutePax5 K198 acetylation regulates gene expression. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01995-7More than 400 people, 80%
Neoadjuvant endocrine therapy may elicit differential responses in Black and white women with breast cancer

Neoadjuvant endocrine therapy may elicit differential responses in Black and white women with breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBlack women treated with neoadjuvant endocrine therapy for breast cancer were more likely to benefit than white women

Neoadjuvant endocrine therapy may elicit differential responses in Black and white women with breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBlack women treated with neoadjuvant endocrine therapy for breast cancer were more likely to benefit than white women