One-cycle cisplatin seems safe for high-risk early testicular cancer

(HealthDay)—For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year m

Updated on: December 20,2023 12

One-cycle cisplatin seems safe for high-risk early testicular cancer

(HealthDay)—For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year m

Updated on:December 20,2023 12

Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on: December 19,2023 10

Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on:December 19,2023 10

Scientists identify gene target to boost effectiveness of cancer immunotherapy

by Katie Marquedant,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainImmune checkpoint inhibitors are important medications that boost the immune system's response against vari

Updated on: December 27,2023 9

Scientists identify gene target to boost effectiveness of cancer immunotherapy

by Katie Marquedant,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainImmune checkpoint inhibitors are important medications that boost the immune system's response against vari

Updated on:December 27,2023 9

New insights into colorectal cancer and E. coli

by Béatrice St-Cyr-Leroux,University of MontrealclbA and bft detection. a clbA and b bft presence in DNA extracted from fecal samples were detected using conventional qualitative PCR. M: marker;

Updated on: December 17,2023 10

New insights into colorectal cancer and E. coli

by Béatrice St-Cyr-Leroux,University of MontrealclbA and bft detection. a clbA and b bft presence in DNA extracted from fecal samples were detected using conventional qualitative PCR. M: marker;

Updated on:December 17,2023 10

Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainPatients with cancers that are driven by certain mutations occurring in response to DNA damage can be safe

Updated on: December 19,2023 10

Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainPatients with cancers that are driven by certain mutations occurring in response to DNA damage can be safe

Updated on:December 19,2023 10

Significant treatment attrition rate seen in multiple myeloma

by Elana GotkineThere is a significant treatment attrition rate in newly diagnosed multiple myeloma (NDMM), according to a study published in the November issue ofLeukemia & Lymphoma.Victor

Updated on: December 21,2023 18

Significant treatment attrition rate seen in multiple myeloma

by Elana GotkineThere is a significant treatment attrition rate in newly diagnosed multiple myeloma (NDMM), according to a study published in the November issue ofLeukemia & Lymphoma.Victor

Updated on:December 21,2023 18

Promising Biomarkers for Early Detection of Prostate Cancer Risk Identified

byColleen Fleisson August 18, 2023A cell metabolism process observed in males who have diabetes and metastatic prostate cancer holds the potential for future advancements in testing and tr

Updated on: December 19,2023 26

Promising Biomarkers for Early Detection of Prostate Cancer Risk Identified

byColleen Fleisson August 18, 2023A cell metabolism process observed in males who have diabetes and metastatic prostate cancer holds the potential for future advancements in testing and tr

Updated on:December 19,2023 26

Multicenter Review Supports TKI Use in Patients With mRCC and Bone Metastases

September 20, 2022Megan HollaschAn analysis of patterns of care and outcomes for patients with metastatic renal cell carcinoma with bone metastases supported the role of TKIs as the standard of care.&

Updated on: October 17,2023 20

Multicenter Review Supports TKI Use in Patients With mRCC and Bone Metastases

September 20, 2022Megan HollaschAn analysis of patterns of care and outcomes for patients with metastatic renal cell carcinoma with bone metastases supported the role of TKIs as the standard of care.&

Updated on:October 17,2023 20

UGN-101 reviewed in real-world upper tract urothelial cancer setting

by Elana GotkineFor patients with upper tract urothelial cancers (UTUCs), the novel therapeutic UGN-101 seems to be effective, with an acceptable safety profile, according to research published online

Updated on: December 17,2023 6

UGN-101 reviewed in real-world upper tract urothelial cancer setting

by Elana GotkineFor patients with upper tract urothelial cancers (UTUCs), the novel therapeutic UGN-101 seems to be effective, with an acceptable safety profile, according to research published online

Updated on:December 17,2023 6

Scientists discover mutations in blood stem cells can exacerbate colon cancer

Compared with normal mice (top), colonoscopies detect more, and larger, tumors in the intestines of mice with clonal hematopoiesis (bottom). Credit: © 2023 Feng et al. Originally published inJou

Updated on: November 02,2023 5

Scientists discover mutations in blood stem cells can exacerbate colon cancer

Compared with normal mice (top), colonoscopies detect more, and larger, tumors in the intestines of mice with clonal hematopoiesis (bottom). Credit: © 2023 Feng et al. Originally published inJou

Updated on:November 02,2023 5

Camrelizumab Plus Nab-Paclitaxel Showcases Antitumor Activity in Platinum-Resistant Urothelial

September 30, 2022Ryan ScottThe combination of camrelizumab and nab-paclitaxel produced encouraging responses in patients with platinum-resistant, unresectable locally advanced or metastatic urothelia

Updated on: October 17,2023 63

Camrelizumab Plus Nab-Paclitaxel Showcases Antitumor Activity in Platinum-Resistant Urothelial

September 30, 2022Ryan ScottThe combination of camrelizumab and nab-paclitaxel produced encouraging responses in patients with platinum-resistant, unresectable locally advanced or metastatic urothelia

Updated on:October 17,2023 63

Coffee might give some men an edge battling prostate cancer

by Cara MurezFor some men battlingprostate cancer,drinking coffee may offer not just a quick pick-me-up but longer survival.Research is still in the early phases, but a new study finds an

Updated on: December 26,2023 10

Coffee might give some men an edge battling prostate cancer

by Cara MurezFor some men battlingprostate cancer,drinking coffee may offer not just a quick pick-me-up but longer survival.Research is still in the early phases, but a new study finds an

Updated on:December 26,2023 10