Cell division, DNA repair and cancer progression closely tied to CDK9 dysfunction

by Sbarro Health Research Organization (SHRO)CDK9 isoforms regulate DNA damage response.AWestern blot analysis of CDK9 in HeLa cells transfected with siRNA CDK9 (siCDK9) or control (siCTR)

Updated on: March 20,2024

Cell division, DNA repair and cancer progression closely tied to CDK9 dysfunction

by Sbarro Health Research Organization (SHRO)CDK9 isoforms regulate DNA damage response.AWestern blot analysis of CDK9 in HeLa cells transfected with siRNA CDK9 (siCDK9) or control (siCTR)

Updated on:March 20,2024

Liquid biopsy has prognostic role in colorectal cancer and potential for guiding therapy

by European Society for Medical OncologyCredit: European Society for Medical OncologyLiquid biopsy is likely to play an increasing role in identifying patients with colorectal cancer (CRC) who ar

Updated on: May 23,2024

Liquid biopsy has prognostic role in colorectal cancer and potential for guiding therapy

by European Society for Medical OncologyCredit: European Society for Medical OncologyLiquid biopsy is likely to play an increasing role in identifying patients with colorectal cancer (CRC) who ar

Updated on:May 23,2024

Thermo-chemotherapy combo eradicates primary and metastatic tumors in mice

by National Institutes of HealthThe theranostic particle is injected into the tail vein. When it reaches the breast tumor, near infrared (NIR) laser light is applied to release the chemotherapy.

Updated on: March 01,2024

Thermo-chemotherapy combo eradicates primary and metastatic tumors in mice

by National Institutes of HealthThe theranostic particle is injected into the tail vein. When it reaches the breast tumor, near infrared (NIR) laser light is applied to release the chemotherapy.

Updated on:March 01,2024

Study identifies new mechanisms that boost p53 signaling and tumor suppression

by Ludwig Cancer ResearchGraphical abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.04.010A team led by Ludwig Stanford's Laura Attardi explored novel mechanisms

Updated on: February 01,2024

Study identifies new mechanisms that boost p53 signaling and tumor suppression

by Ludwig Cancer ResearchGraphical abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.04.010A team led by Ludwig Stanford's Laura Attardi explored novel mechanisms

Updated on:February 01,2024

UK underwear gets cancer warning labels

Credit: CC0 Public DomainUK supermarket chain Morrisons said on Monday it had joined forces with the state-run National Health Service to put advice labels on underwear about the early warning signs o

Updated on: February 03,2024

UK underwear gets cancer warning labels

Credit: CC0 Public DomainUK supermarket chain Morrisons said on Monday it had joined forces with the state-run National Health Service to put advice labels on underwear about the early warning signs o

Updated on:February 03,2024

Research is uncovering new ways to treat an aggressive brain cancer

by Anthony King,Horizon: The EU Research & Innovation MagazineCredit: AI-generated imageBrain surgeons need steady hands as well as cool heads. Now they're getting a helping hand from re

Updated on: February 03,2024

Research is uncovering new ways to treat an aggressive brain cancer

by Anthony King,Horizon: The EU Research & Innovation MagazineCredit: AI-generated imageBrain surgeons need steady hands as well as cool heads. Now they're getting a helping hand from re

Updated on:February 03,2024

In the fight against breast cancer, researchers identify malignancy hibernation as the next battleground

by University of Massachusetts AmherstTreatment approaches for breast cancer dormancy. Plausible therapeutic pathway targets to (A) directly kill, (B) maintain, or (C) activate and then kill dorm

Updated on: March 30,2024

In the fight against breast cancer, researchers identify malignancy hibernation as the next battleground

by University of Massachusetts AmherstTreatment approaches for breast cancer dormancy. Plausible therapeutic pathway targets to (A) directly kill, (B) maintain, or (C) activate and then kill dorm

Updated on:March 30,2024

Combined MET and PD-L1 inhibition shows promise in MET-driven metastatic papillary renal cancer

by Vall d'Hebron Institute of OncologyCredit: Pixabay/CC0 Public DomainAdvanced papillary renal cancer (PRC) has a poor prognosis with few treatment options available. Approximately 30% of patient

Updated on: December 28,2023

Combined MET and PD-L1 inhibition shows promise in MET-driven metastatic papillary renal cancer

by Vall d'Hebron Institute of OncologyCredit: Pixabay/CC0 Public DomainAdvanced papillary renal cancer (PRC) has a poor prognosis with few treatment options available. Approximately 30% of patient

Updated on:December 28,2023

Combination drug activates calcium channels to trigger deadly influx of calcium ions inside tumor cells

JANUARY 29, 2024byWileyCredit:Angewandte Chemie International Edition(2024). DOI: 10.1002/anie.202317578Calcium ions are essential for cells, but can be toxic in higher concentration

Updated on: March 25,2024

Combination drug activates calcium channels to trigger deadly influx of calcium ions inside tumor cells

JANUARY 29, 2024byWileyCredit:Angewandte Chemie International Edition(2024). DOI: 10.1002/anie.202317578Calcium ions are essential for cells, but can be toxic in higher concentration

Updated on:March 25,2024

Newfound cancer cell biology suggests which patients will respond to immunotherapy

byNYU Langone HealthCredit: Pixabay/CC0 Public DomainPatients with head and neck cancer who have more genetic material on chromosome 9 in their cancer cells survive three times longer after rece

Updated on: January 13,2024

Newfound cancer cell biology suggests which patients will respond to immunotherapy

byNYU Langone HealthCredit: Pixabay/CC0 Public DomainPatients with head and neck cancer who have more genetic material on chromosome 9 in their cancer cells survive three times longer after rece

Updated on:January 13,2024

Exploring the role of RNA modification in normal hematopoiesis and acute myeloid leukemia pathogenesis

by Cactus CommunicationsThe review sheds light on the role of post-transcriptional RNA modifications in normal hematopoietic development and acute myeloid leukemia, and highlights novel therapeutic ta

Updated on: April 28,2024

Exploring the role of RNA modification in normal hematopoiesis and acute myeloid leukemia pathogenesis

by Cactus CommunicationsThe review sheds light on the role of post-transcriptional RNA modifications in normal hematopoietic development and acute myeloid leukemia, and highlights novel therapeutic ta

Updated on:April 28,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on: February 20,2024

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on:February 20,2024