Putting liquid biopsies on solid ground: Cancer diagnosis from a milliliter of blood

byWeizmann Institute of ScienceSingle-molecule DNA sequencing technical setup. Schematic representation of key instrumentation used to perform single-molecule DNA sequencing. Straight and dashed

Updated on: December 19,2023 12

Putting liquid biopsies on solid ground: Cancer diagnosis from a milliliter of blood

byWeizmann Institute of ScienceSingle-molecule DNA sequencing technical setup. Schematic representation of key instrumentation used to perform single-molecule DNA sequencing. Straight and dashed

Updated on:December 19,2023 12

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom

Updated on: October 30,2023 10

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom

Updated on:October 30,2023 10

Molecular map reveals insights into the genetic drivers of chronic lymphocytic leukemia

byMassachusetts General HospitalCredit: Unsplash/CC0 Public DomainA newly constructed map of the landscape of genetic changes in chronic lymphocytic leukemia (CLL), a type of cancer of the blood

Updated on: December 18,2023 23

Molecular map reveals insights into the genetic drivers of chronic lymphocytic leukemia

byMassachusetts General HospitalCredit: Unsplash/CC0 Public DomainA newly constructed map of the landscape of genetic changes in chronic lymphocytic leukemia (CLL), a type of cancer of the blood

Updated on:December 18,2023 23

Genetic analysis of the most common type of bladder cancer yields guidance on treatment options

byUNC Lineberger Comprehensive Cancer CenterUC-GENOME study design and molecular subtyping shows enrichment of Stroma-rich primary tumors in metastatic datasets. Credit:Nature Communicatio

Updated on: December 21,2023 10

Genetic analysis of the most common type of bladder cancer yields guidance on treatment options

byUNC Lineberger Comprehensive Cancer CenterUC-GENOME study design and molecular subtyping shows enrichment of Stroma-rich primary tumors in metastatic datasets. Credit:Nature Communicatio

Updated on:December 21,2023 10

Multi-center study sheds light on understudied breast cancer type

byUniversity of PittsburghCredit: Pixabay/CC0 Public DomainA multi-center analysis of patients with invasive lobular carcinoma, or ILC—the second most common histological subtype of invasive bre

Updated on: December 21,2023 8

Multi-center study sheds light on understudied breast cancer type

byUniversity of PittsburghCredit: Pixabay/CC0 Public DomainA multi-center analysis of patients with invasive lobular carcinoma, or ILC—the second most common histological subtype of invasive bre

Updated on:December 21,2023 8

Talazoparib + enzalutamide beneficial in metastatic prostate cancer

by Elana GotkineFor patients with metastatic castration-resistant prostate cancer (mCRPC), treatment with talazoparib (TALA) plus enzalutamide (ENZA) is better than placebo (PBO) plus ENZA, according

Updated on: December 17,2023 10

Talazoparib + enzalutamide beneficial in metastatic prostate cancer

by Elana GotkineFor patients with metastatic castration-resistant prostate cancer (mCRPC), treatment with talazoparib (TALA) plus enzalutamide (ENZA) is better than placebo (PBO) plus ENZA, according

Updated on:December 17,2023 10

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on: December 26,2023 10

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on:December 26,2023 10

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on: December 20,2023 10

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on:December 20,2023 10

Scientists develop a cancer vaccine to simultaneously kill and prevent brain cancer

byBrigham and Women's HospitalScientists developed a bifunctional therapeutic strategy by transforming living tumor cells into a therapeutic. Shah’s team engineered living tumor cells using

Updated on: December 27,2023 6

Scientists develop a cancer vaccine to simultaneously kill and prevent brain cancer

byBrigham and Women's HospitalScientists developed a bifunctional therapeutic strategy by transforming living tumor cells into a therapeutic. Shah’s team engineered living tumor cells using

Updated on:December 27,2023 6

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR

Updated on: December 26,2023 10

Refined method to peer into cancer cells' inner working unlocks the interactome

byJosep Carreras Leukaemia Research InstituteliCHi-C identifies cell types presumably implicated in disease etiology. A Enrichment of GWAS summary statistics at promoter-interacting regions (PIR

Updated on:December 26,2023 10

Cancer Gene Census paves the way for improvements in personalised medicine

byWellcome Trust Sanger InstituteCredit: Wellcome Trust Sanger InstituteResearchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involve

Updated on: December 18,2023 16

Cancer Gene Census paves the way for improvements in personalised medicine

byWellcome Trust Sanger InstituteCredit: Wellcome Trust Sanger InstituteResearchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involve

Updated on:December 18,2023 16

Survival rates high for children, teens with melanoma

by Lori SolomonSurvival rates for children and adolescents with melanomas are high, according to a study published online Dec. 9 in theJournal of the American Academy of Dermatology.Mary-Ann El

Updated on: December 21,2023 9

Survival rates high for children, teens with melanoma

by Lori SolomonSurvival rates for children and adolescents with melanomas are high, according to a study published online Dec. 9 in theJournal of the American Academy of Dermatology.Mary-Ann El

Updated on:December 21,2023 9