Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023 10

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023 10

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on: December 20,2023 12

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on:December 20,2023 12

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compar

Updated on: November 07,2023 17

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compar

Updated on:November 07,2023 17

Detailed diagnosis boosts child cancer survival

byCancer Research UK| News6 March 2009More accurate disease classification now means some young children with neuroblastoma will have less intensive treatment with better survival, accordi

Updated on: December 19,2023 8

Detailed diagnosis boosts child cancer survival

byCancer Research UK| News6 March 2009More accurate disease classification now means some young children with neuroblastoma will have less intensive treatment with better survival, accordi

Updated on:December 19,2023 8

Two cancer-causing genes work together to promote metastasis

byeLifeCredit: CC0 Public DomainCancer-promoting genes MYC and TWIST1 co-opt immune system cells to enable cancer cells to spread, but blocking a key step in this process can help prevent the di

Updated on: December 20,2023 21

Two cancer-causing genes work together to promote metastasis

byeLifeCredit: CC0 Public DomainCancer-promoting genes MYC and TWIST1 co-opt immune system cells to enable cancer cells to spread, but blocking a key step in this process can help prevent the di

Updated on:December 20,2023 21

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on: December 22,2023 22

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on:December 22,2023 22

Step forward in leukemia treatment

by South Australian Health and Medical Research InstituteCredit: AI-generated imageAn international clinical trial involving Adelaide researchers has demonstrated the safety and efficacy of a next-gen

Updated on: December 22,2023 16

Step forward in leukemia treatment

by South Australian Health and Medical Research InstituteCredit: AI-generated imageAn international clinical trial involving Adelaide researchers has demonstrated the safety and efficacy of a next-gen

Updated on:December 22,2023 16

Results mixed for twice-daily APBI in early breast cancer

(HealthDay)—Accelerated partial breast irradiation (APBI) delivered twice per day over one week to the tumor bed is noninferior to whole breast irradiation for preventing ipsilateral breast tumor recu

Updated on: December 22,2023 11

Results mixed for twice-daily APBI in early breast cancer

(HealthDay)—Accelerated partial breast irradiation (APBI) delivered twice per day over one week to the tumor bed is noninferior to whole breast irradiation for preventing ipsilateral breast tumor recu

Updated on:December 22,2023 11

Why some cancers affect only young women

byUniversity of GenevaCredit: CC0 Public DomainAmong several forms of pancreatic cancer, one of them specifically affects women, often young. How is this possible, even though the pancreas is an

Updated on: December 18,2023 18

Why some cancers affect only young women

byUniversity of GenevaCredit: CC0 Public DomainAmong several forms of pancreatic cancer, one of them specifically affects women, often young. How is this possible, even though the pancreas is an

Updated on:December 18,2023 18

Conversation tool to help cancer patients with treatment choices

byLeiden UniversityCredit: Pixabay/CC0 Public DomainResearchers at the Leiden Institute of Advanced Computer Science (LIACS) are collaborating on the development of a conversation tool for patie

Updated on: December 21,2023 10

Conversation tool to help cancer patients with treatment choices

byLeiden UniversityCredit: Pixabay/CC0 Public DomainResearchers at the Leiden Institute of Advanced Computer Science (LIACS) are collaborating on the development of a conversation tool for patie

Updated on:December 21,2023 10

What Comes after NCI-MATCH? NCI’s New Precision Medicine Cancer Trials

SubscribeDecember 6, 2023, by James H. Doroshow, M.D.Findings from NCI-MATCH and its successor trials will help oncologists implement precision medicine in everyday patient care.Credit: iStockMore tha

Updated on: December 19,2023 45

What Comes after NCI-MATCH? NCI’s New Precision Medicine Cancer Trials

SubscribeDecember 6, 2023, by James H. Doroshow, M.D.Findings from NCI-MATCH and its successor trials will help oncologists implement precision medicine in everyday patient care.Credit: iStockMore tha

Updated on:December 19,2023 45

Molecular delivery system developed at URI shows promise against bladder cancer

byUniversity of Rhode IslandpHLIP-ICG can locate cancerous lesions and illuminate them with a fluorescent molecule, making them potentially easier for surgeons to see and remove. Credit: URIA re

Updated on: December 17,2023 9

Molecular delivery system developed at URI shows promise against bladder cancer

byUniversity of Rhode IslandpHLIP-ICG can locate cancerous lesions and illuminate them with a fluorescent molecule, making them potentially easier for surgeons to see and remove. Credit: URIA re

Updated on:December 17,2023 9