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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Cancer drug cooperation could save 1.5 mn lives a year: researchers

Cancer drug cooperation could save 1.5 mn lives a year: researchers

Credit: Pixabay/CC0 Public DomainAround 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.The figure was based

Cancer drug cooperation could save 1.5 mn lives a year: researchers

Credit: Pixabay/CC0 Public DomainAround 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.The figure was based
ASCO: liquid biopsy accurate for detecting colorectal cancer

ASCO: liquid biopsy accurate for detecting colorectal cancer

(HealthDay)—Liquid biopsy that identifies circulating tumor cells in a blood sample has high accuracy for detecting colorectal cancer (CRC), according to a study presented at the American Society of C

ASCO: liquid biopsy accurate for detecting colorectal cancer

(HealthDay)—Liquid biopsy that identifies circulating tumor cells in a blood sample has high accuracy for detecting colorectal cancer (CRC), according to a study presented at the American Society of C
New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity

New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity

by Institute of Cancer ResearchAcute depletion of SET1/COMPASS core subunits reveals rapid turnover of H3K4me3.a, Schematic of the degron systems for the targeted degradation of DPY30 and R

New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity

by Institute of Cancer ResearchAcute depletion of SET1/COMPASS core subunits reveals rapid turnover of H3K4me3.a, Schematic of the degron systems for the targeted degradation of DPY30 and R
Researchers develop liquid biopsy test for pediatric solid tumors

Researchers develop liquid biopsy test for pediatric solid tumors

by Children's Hospital Los AngelesCopy number alteration detection in liquid biopsies of pediatric solid tumor patients. Summary of copy number alteration (CNA) detection and disease status a

Researchers develop liquid biopsy test for pediatric solid tumors

by Children's Hospital Los AngelesCopy number alteration detection in liquid biopsies of pediatric solid tumor patients. Summary of copy number alteration (CNA) detection and disease status a
Those with the BRCA1 gene mutation may face greater risk for aggressive cancer caused by asbestos exposure

Those with the BRCA1 gene mutation may face greater risk for aggressive cancer caused by asbestos exposure

byNagoya UniversityChrysotile-induced MMs present lower expression levels of Brca1. (A) Immunohistochemistry (IHC) staining of total BRCA1 on MM samples (bar=25 μm; N≧7).

Those with the BRCA1 gene mutation may face greater risk for aggressive cancer caused by asbestos exposure

byNagoya UniversityChrysotile-induced MMs present lower expression levels of Brca1. (A) Immunohistochemistry (IHC) staining of total BRCA1 on MM samples (bar=25 μm; N≧7).
Precision oncology insights revealed for colorectal cancer

Precision oncology insights revealed for colorectal cancer

by UNC Lineberger Comprehensive Cancer CenterCredit: CC0 Public DomainNext-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to

Precision oncology insights revealed for colorectal cancer

by UNC Lineberger Comprehensive Cancer CenterCredit: CC0 Public DomainNext-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to
Why do cancer patients lose weight? Study points to elevated lactate levels

Why do cancer patients lose weight? Study points to elevated lactate levels

byNature Publishing GroupSchematic illustration depicting the signaling cascade downstream of lactate/GPR81 in promoting cancer cachexia. Credit:Nature Metabolism(2024). DOI: 10.1038

Why do cancer patients lose weight? Study points to elevated lactate levels

byNature Publishing GroupSchematic illustration depicting the signaling cascade downstream of lactate/GPR81 in promoting cancer cachexia. Credit:Nature Metabolism(2024). DOI: 10.1038
Researchers discover link between PSA level at time of salvage therapy following surgery and risk of death

Researchers discover link between PSA level at time of salvage therapy following surgery and risk of death

by Brigham and Women's HospitalAdjusted estimates of ACM among men illustrating the difference in these estimated among patients in the time-dependent treatment groups of no RT, aRT, salvage

Researchers discover link between PSA level at time of salvage therapy following surgery and risk of death

by Brigham and Women's HospitalAdjusted estimates of ACM among men illustrating the difference in these estimated among patients in the time-dependent treatment groups of no RT, aRT, salvage
EU approves treatment for prostate cancer

EU approves treatment for prostate cancer

Prostate cancer cells. Credit: NIH Image GalleryThe European Union has approved a new treatment against an advanced type of prostate cancer by Novartis, the Swiss pharmaceutical giant said Tuesday.The

EU approves treatment for prostate cancer

Prostate cancer cells. Credit: NIH Image GalleryThe European Union has approved a new treatment against an advanced type of prostate cancer by Novartis, the Swiss pharmaceutical giant said Tuesday.The
Turncoat T cells: When exhausted, cancer-fighting T cells may switch sides

Turncoat T cells: When exhausted, cancer-fighting T cells may switch sides

byUniversity of PittsburghGreg Delgoffe, Ph.D., associate professor of immunology at Pitt’s School of Medicine and director of the Tumor Microenvironment Center at UPMC Hillman Cancer Center. Cr

Turncoat T cells: When exhausted, cancer-fighting T cells may switch sides

byUniversity of PittsburghGreg Delgoffe, Ph.D., associate professor of immunology at Pitt’s School of Medicine and director of the Tumor Microenvironment Center at UPMC Hillman Cancer Center. Cr
'Bet hedging' explains the efficacy of many combination cancer therapies

'Bet hedging' explains the efficacy of many combination cancer therapies

by Harvard Medical SchoolKiller T cells surround a cancer cell. Credit: NIHThe efficacy of many FDA-approved cancer drug combinations is not due to synergistic interactions between drugs, but rat

'Bet hedging' explains the efficacy of many combination cancer therapies

by Harvard Medical SchoolKiller T cells surround a cancer cell. Credit: NIHThe efficacy of many FDA-approved cancer drug combinations is not due to synergistic interactions between drugs, but rat
Molecular mechanisms regulating prostate cancer hypoxia identified

Molecular mechanisms regulating prostate cancer hypoxia identified

by Melissa Rohman,Northwestern UniversityMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0A Northwestern Medicine

Molecular mechanisms regulating prostate cancer hypoxia identified

by Melissa Rohman,Northwestern UniversityMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0A Northwestern Medicine