Drug combination provides a one-two punch attack against colorectal cancer

by National Cancer InstituteOn the left,SN38, the active metabolite of irinotecan, traps TOP1 on DNA, forming TOP1 cleavage complexes that are degraded upon their formation, as seen by the

Updated on: January 29,2024 10

Drug combination provides a one-two punch attack against colorectal cancer

by National Cancer InstituteOn the left,SN38, the active metabolite of irinotecan, traps TOP1 on DNA, forming TOP1 cleavage complexes that are degraded upon their formation, as seen by the

Updated on:January 29,2024 10

Using AI during cancer-screening results in more recommended controls

by Mathilde Coraline Aarvold Bakke,University of OsloGraphical abstract. Credit:Clinical Gastroenterology and Hepatology(2022). DOI: 10.1016/j.cgh.2022.08.022A polyp is a small growt

Updated on: January 29,2024 16

Using AI during cancer-screening results in more recommended controls

by Mathilde Coraline Aarvold Bakke,University of OsloGraphical abstract. Credit:Clinical Gastroenterology and Hepatology(2022). DOI: 10.1016/j.cgh.2022.08.022A polyp is a small growt

Updated on:January 29,2024 16

Finally, a tool to predict response to chemotherapy before bladder cancer surgery

by CU Anschutz Medical CampusThomas Flaig, MD, and colleagues show that COXEN may predict which patients will respond to chemotherapy before bladder cancer surgery Credit: University of Colorado

Updated on: March 21,2024 20

Finally, a tool to predict response to chemotherapy before bladder cancer surgery

by CU Anschutz Medical CampusThomas Flaig, MD, and colleagues show that COXEN may predict which patients will respond to chemotherapy before bladder cancer surgery Credit: University of Colorado

Updated on:March 21,2024 20

Researchers develop an algorithm to improve cancer treatment

by Josh Barney,University of VirginiaOverview of KSTAR algorithm. First, we heuristically prune dense and highly overlapping weighted kinase-substrate prediction graphs from NetworKIN into many

Updated on: February 18,2024 20

Researchers develop an algorithm to improve cancer treatment

by Josh Barney,University of VirginiaOverview of KSTAR algorithm. First, we heuristically prune dense and highly overlapping weighted kinase-substrate prediction graphs from NetworKIN into many

Updated on:February 18,2024 20

Team uncovers promising lead in genetic approach to treating glioblastoma

by Anna C. Christensen,University of ArizonaBaldassarre Stea, MD, PhD, (center), treats brain tumors with DNA-damaging radiation. Credit: Anna C. ChristensenGlioblastoma, a deadly brain cancer t

Updated on: May 27,2024 5

Team uncovers promising lead in genetic approach to treating glioblastoma

by Anna C. Christensen,University of ArizonaBaldassarre Stea, MD, PhD, (center), treats brain tumors with DNA-damaging radiation. Credit: Anna C. ChristensenGlioblastoma, a deadly brain cancer t

Updated on:May 27,2024 5

Osimertinib with savolitinib demonstrates stronger efficacy than osimertinib alone in some patients

by International Association for the Study of Lung CancerCredit: Unsplash/CC0 Public DomainThe combination of osimertinib and savolitinib showed clinically meaningful improvement in objective response

Updated on: September 27,2024 0

Osimertinib with savolitinib demonstrates stronger efficacy than osimertinib alone in some patients

by International Association for the Study of Lung CancerCredit: Unsplash/CC0 Public DomainThe combination of osimertinib and savolitinib showed clinically meaningful improvement in objective response

Updated on:September 27,2024 0

Study: Risk of cancer doubles for people with 'skewed' blood cells

by King's College LondonAge acquired XCI-skew across age groups and time. (A) A histogram displaying the age distribution of the TwinsUK HUMARA cohort (age range: 19–99; median age = 61). (B)

Updated on: January 30,2024 17

Study: Risk of cancer doubles for people with 'skewed' blood cells

by King's College LondonAge acquired XCI-skew across age groups and time. (A) A histogram displaying the age distribution of the TwinsUK HUMARA cohort (age range: 19–99; median age = 61). (B)

Updated on:January 30,2024 17

Access to cancer care can be just as important as care itself, new paper says

by Leslie Cantu,Medical University of South CarolinaCredit: Pixabay/CC0 Public DomainThe first step in addressing cancer is getting to your doctors' appointments. But that's not so easy

Updated on: February 03,2024 11

Access to cancer care can be just as important as care itself, new paper says

by Leslie Cantu,Medical University of South CarolinaCredit: Pixabay/CC0 Public DomainThe first step in addressing cancer is getting to your doctors' appointments. But that's not so easy

Updated on:February 03,2024 11

Study reveals potential target for precision colorectal cancer treatment

by Mallory Locklear,Yale UniversityFlowchart outlining the study. A: Metabolomics data collection and analysis; including targeted analysis of metabolites involved in ferroptosis pathways; B: Id

Updated on: February 18,2024 15

Study reveals potential target for precision colorectal cancer treatment

by Mallory Locklear,Yale UniversityFlowchart outlining the study. A: Metabolomics data collection and analysis; including targeted analysis of metabolites involved in ferroptosis pathways; B: Id

Updated on:February 18,2024 15

Effect of religiosity/spirituality on ovarian cancer diagnosis in African American women

by Mary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersAn examination of data from a multi-center case-control study of ovarian cancer in African American women found that women who re

Updated on: April 01,2024 16

Effect of religiosity/spirituality on ovarian cancer diagnosis in African American women

by Mary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersAn examination of data from a multi-center case-control study of ovarian cancer in African American women found that women who re

Updated on:April 01,2024 16

Renowned tumor suppressor has prominent role in tissue repair, study finds

by Krista Conger,Stanford UniversityCredit: AI-generated imageA protein famed among scientists and clinicians for its ability to suppress the development of many types of tumors may just be moon

Updated on: January 23,2024 13

Renowned tumor suppressor has prominent role in tissue repair, study finds

by Krista Conger,Stanford UniversityCredit: AI-generated imageA protein famed among scientists and clinicians for its ability to suppress the development of many types of tumors may just be moon

Updated on:January 23,2024 13

Researchers create a cell therapy based on STAb cells for a type of leukemia with few treatment options

by Josep Carreras Leukaemia Research InstituteComparative in vitro study of engineered CD1a-STAb and CD1a-CAR T cells. (A, B) Schematic diagrams showing the genetic (A) and domain structure (B) o

Updated on: February 18,2024 14

Researchers create a cell therapy based on STAb cells for a type of leukemia with few treatment options

by Josep Carreras Leukaemia Research InstituteComparative in vitro study of engineered CD1a-STAb and CD1a-CAR T cells. (A, B) Schematic diagrams showing the genetic (A) and domain structure (B) o

Updated on:February 18,2024 14