Researchers gain structural insights into the immune modulator Siglec-15 and its interaction with T cells

by CIC bioGUNEa Cartoon and surface representation of two views of the crystal structure of Siglec-15 in complex with anti-Siglec-15 5G12 Fab. 5G12 is composed of a heavy chain (HC) (in orange) and a

Updated on: February 18,2024

Researchers gain structural insights into the immune modulator Siglec-15 and its interaction with T cells

by CIC bioGUNEa Cartoon and surface representation of two views of the crystal structure of Siglec-15 in complex with anti-Siglec-15 5G12 Fab. 5G12 is composed of a heavy chain (HC) (in orange) and a

Updated on:February 18,2024

Researchers identify innovative strategy with potential to enhance bowel cancer treatment

by University of GalwayGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112475Researchers at University of Galway studying cell interactions in bowel cancer h

Updated on: February 18,2024

Researchers identify innovative strategy with potential to enhance bowel cancer treatment

by University of GalwayGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112475Researchers at University of Galway studying cell interactions in bowel cancer h

Updated on:February 18,2024

Study validates diagnostic assay for Asian cancers

by National University of SingaporeGraphical overview of workflow and coverage of cancer subtypes in the Asian Pan-Cancer Panel. A total of six workdays are required from sample QC to reliable ge

Updated on: February 20,2024

Study validates diagnostic assay for Asian cancers

by National University of SingaporeGraphical overview of workflow and coverage of cancer subtypes in the Asian Pan-Cancer Panel. A total of six workdays are required from sample QC to reliable ge

Updated on:February 20,2024

Study results show conjugate therapy produced remissions in one-third of patients with drug-resistant ovarian cancer

by Dana-Farber Cancer InstituteAntitumor activity of mirvetuximab soravtansine. (A) Maximum percentage change in target lesion size from baseline. Best response according to RECIST is indicated b

Updated on: January 30,2024

Study results show conjugate therapy produced remissions in one-third of patients with drug-resistant ovarian cancer

by Dana-Farber Cancer InstituteAntitumor activity of mirvetuximab soravtansine. (A) Maximum percentage change in target lesion size from baseline. Best response according to RECIST is indicated b

Updated on:January 30,2024

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on: January 22,2024

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on:January 22,2024

How the tumor microenvironment stimulates pancreatic cancer growth and progression

by Nancy Fliesler,Children's Hospital BostonMyeloid-specific deletion of LRP1 inhibits tumor growth by preventing the repression of Tsp-1. A Plot of percentage of LRP1 + multiple myeloid and

Updated on: January 22,2024

How the tumor microenvironment stimulates pancreatic cancer growth and progression

by Nancy Fliesler,Children's Hospital BostonMyeloid-specific deletion of LRP1 inhibits tumor growth by preventing the repression of Tsp-1. A Plot of percentage of LRP1 + multiple myeloid and

Updated on:January 22,2024

Predicting immunotherapy response and guiding combination therapy with MOTIF

byScience China PressWorkflow of MOTIF and three main application including cellular function analysis, immunotherapy response prediction and combinational therapy guidance. Credit: Science Chin

Updated on: March 30,2024

Predicting immunotherapy response and guiding combination therapy with MOTIF

byScience China PressWorkflow of MOTIF and three main application including cellular function analysis, immunotherapy response prediction and combinational therapy guidance. Credit: Science Chin

Updated on:March 30,2024

Potential overtreatment during life-limiting illness and end of life in older adults

by Gunilla Sonnebring,Karolinska InstitutetCredit: CC0 Public DomainA new thesis from Karolinska Institutet advocates end-of-life care that prioritizes the highest possible quality of life, avoi

Updated on: April 22,2024

Potential overtreatment during life-limiting illness and end of life in older adults

by Gunilla Sonnebring,Karolinska InstitutetCredit: CC0 Public DomainA new thesis from Karolinska Institutet advocates end-of-life care that prioritizes the highest possible quality of life, avoi

Updated on:April 22,2024

Nutritional cues regulate pancreatic tumor's 'cell drinking'

by Sanford Burnham Prebys Medical Discovery InstituteCosimo Commisso, Ph.D., assistant professor in Sanford Burnham Prebys' NCI-designated Cancer Center. Credit: Sanford Burnham PrebysDespera

Updated on: May 11,2024

Nutritional cues regulate pancreatic tumor's 'cell drinking'

by Sanford Burnham Prebys Medical Discovery InstituteCosimo Commisso, Ph.D., assistant professor in Sanford Burnham Prebys' NCI-designated Cancer Center. Credit: Sanford Burnham PrebysDespera

Updated on:May 11,2024

Study sheds light on the mysterious evolution of DNA rings in tumors

by Charité - Universitätsmedizin BerlinNuclei and chromosomes of neuroblastoma cells. DNA rings are colored yellow, turquoise, or magenta. Each color is associated with different cancer genes. ©

Updated on: February 03,2024

Study sheds light on the mysterious evolution of DNA rings in tumors

by Charité - Universitätsmedizin BerlinNuclei and chromosomes of neuroblastoma cells. DNA rings are colored yellow, turquoise, or magenta. Each color is associated with different cancer genes. ©

Updated on:February 03,2024

In fight against prostate cancer, caring for mental health is a growing priority

by Anthony King,Horizon: The EU Research & Innovation MagazineCredit: AI-generated imageProstate cancer is the second most common cancer in men and its diagnosis—and treatment—can take a tol

Updated on: February 03,2024

In fight against prostate cancer, caring for mental health is a growing priority

by Anthony King,Horizon: The EU Research & Innovation MagazineCredit: AI-generated imageProstate cancer is the second most common cancer in men and its diagnosis—and treatment—can take a tol

Updated on:February 03,2024

Putting the brakes on tumor stealth

by Monash UniversityDr. Richard Berry with lab members Dr. Gabby Watson, Zhihui Fu and Felix Deuss. Credit: Monash UniversityNew research undertaken at Monash University has shed new light on how

Updated on: April 01,2024

Putting the brakes on tumor stealth

by Monash UniversityDr. Richard Berry with lab members Dr. Gabby Watson, Zhihui Fu and Felix Deuss. Credit: Monash UniversityNew research undertaken at Monash University has shed new light on how

Updated on:April 01,2024