Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on: February 18,2024

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on:February 18,2024

Adding pembrolizumab to chemo improves survival in cervical cancer, finds study

by Elana GotkineFor women with persistent, recurrent, or metastatic cervical cancer, adding pembrolizumab to chemotherapy, with or without bevacizumab, is associated with improved overall and progress

Updated on: January 23,2024

Adding pembrolizumab to chemo improves survival in cervical cancer, finds study

by Elana GotkineFor women with persistent, recurrent, or metastatic cervical cancer, adding pembrolizumab to chemotherapy, with or without bevacizumab, is associated with improved overall and progress

Updated on:January 23,2024

Researchers identify protein that may protect the heart during certain cancer treatment regimens

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCirculating Hpx is elevated in mice treated with Dox. (A) Dox-induced chronic cardiomyopathy model in mice. i.p., intraperitoneally. (B

Updated on: February 18,2024

Researchers identify protein that may protect the heart during certain cancer treatment regimens

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCirculating Hpx is elevated in mice treated with Dox. (A) Dox-induced chronic cardiomyopathy model in mice. i.p., intraperitoneally. (B

Updated on:February 18,2024

Novel treatment effective for bladder cancer, study in mice shows

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainAn epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by

Updated on: February 01,2024

Novel treatment effective for bladder cancer, study in mice shows

by Northwestern UniversityCredit: Unsplash/CC0 Public DomainAn epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by

Updated on:February 01,2024

Three ways to encourage kids to be more charitable and kind this holiday season

by Hali Kil,The ConversationCredit: Unsplash/CC0 Public DomainWith the holiday season just around the corner, families and households will soon be gathering to give and receive gifts. Many will

Updated on: April 20,2024

Three ways to encourage kids to be more charitable and kind this holiday season

by Hali Kil,The ConversationCredit: Unsplash/CC0 Public DomainWith the holiday season just around the corner, families and households will soon be gathering to give and receive gifts. Many will

Updated on:April 20,2024

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on: May 09,2024

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on:May 09,2024

A new targeted treatment shows promise for select patients with stomach cancer

byWeill Cornell Medical CollegeCredit: Pixabay/CC0 Public DomainAn international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, has found tha

Updated on: January 29,2024

A new targeted treatment shows promise for select patients with stomach cancer

byWeill Cornell Medical CollegeCredit: Pixabay/CC0 Public DomainAn international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, has found tha

Updated on:January 29,2024

New imaging technique improves accuracy of diagnosis for most common skin cancer

by European Academy of Dermatology and VenereologyCredit: Unsplash/CC0 Public DomainA novel imaging technique significantly improves the accuracy of the diagnosis of basal cell carcinoma (BCC)—the mos

Updated on: January 11,2024

New imaging technique improves accuracy of diagnosis for most common skin cancer

by European Academy of Dermatology and VenereologyCredit: Unsplash/CC0 Public DomainA novel imaging technique significantly improves the accuracy of the diagnosis of basal cell carcinoma (BCC)—the mos

Updated on:January 11,2024

New blood test for noncoding RNA significantly improves cancer detection

byUniversity of California - Santa CruzCell-free RNA transcriptome profiling using repeat-aware COMPLETE-seq.a, Diagram of COMPLETE-seq RNA liquid-biopsy technology, highlighting the use o

Updated on: January 11,2024

New blood test for noncoding RNA significantly improves cancer detection

byUniversity of California - Santa CruzCell-free RNA transcriptome profiling using repeat-aware COMPLETE-seq.a, Diagram of COMPLETE-seq RNA liquid-biopsy technology, highlighting the use o

Updated on:January 11,2024

Exploring CAR T-cell therapy for aggressive follicular lymphoma

by Olivia Dimmer,Northwestern UniversityORR by best overall response per IRC assessment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02986-9CAR T-cell therapy is an effecti

Updated on: August 01,2024

Exploring CAR T-cell therapy for aggressive follicular lymphoma

by Olivia Dimmer,Northwestern UniversityORR by best overall response per IRC assessment. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02986-9CAR T-cell therapy is an effecti

Updated on:August 01,2024

Experts explain treatment options for a common cancer complication

byThe Endocrine SocietyOsteoclast formation, activity, and pharmacologic inhibition. (A) Osteoclasts develop from osteoclast precursor cells when receptor activator of nuclear factor κ B (RANK)

Updated on: January 22,2024

Experts explain treatment options for a common cancer complication

byThe Endocrine SocietyOsteoclast formation, activity, and pharmacologic inhibition. (A) Osteoclasts develop from osteoclast precursor cells when receptor activator of nuclear factor κ B (RANK)

Updated on:January 22,2024

Researchers invent a new class of AI to improve cancer research and treatments

by Colette Gallagher,Mayo ClinicCredit: Mayo ClinicMayo Clinic researchers recently invented a new class of artificial intelligence (AI) algorithms called hypothesis-driven AI that are a signifi

Updated on: March 20,2024

Researchers invent a new class of AI to improve cancer research and treatments

by Colette Gallagher,Mayo ClinicCredit: Mayo ClinicMayo Clinic researchers recently invented a new class of artificial intelligence (AI) algorithms called hypothesis-driven AI that are a signifi

Updated on:March 20,2024