Trials supporting FDA approval of breakthrough drugs examined

(HealthDay)—Pivotal trials supporting U.S. Food and Drug Administration approvals granted Breakthrough Therapy designation often lack randomization, double-blinding, and control groups, according to a

Updated on: April 14,2024 18

Trials supporting FDA approval of breakthrough drugs examined

(HealthDay)—Pivotal trials supporting U.S. Food and Drug Administration approvals granted Breakthrough Therapy designation often lack randomization, double-blinding, and control groups, according to a

Updated on:April 14,2024 18

A new drug target identified for diseases associated with leukemia-causing virus

by Christine Yu,Pennsylvania State UniversityKDR inhibition induces autophagic/lysosomal degradation of Tax. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-49737-5A team

Updated on: August 06,2024 0

A new drug target identified for diseases associated with leukemia-causing virus

by Christine Yu,Pennsylvania State UniversityKDR inhibition induces autophagic/lysosomal degradation of Tax. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-49737-5A team

Updated on:August 06,2024 0

Mathematical methods for diagnosing breast cancer

by Kaunas University of Technology100 microscope images of breast tissue were analyzed in order to teach computer to recognize malignancy; 85 percent accuracy rate was achieved. Credit: KTUA team

Updated on: April 14,2024 20

Mathematical methods for diagnosing breast cancer

by Kaunas University of Technology100 microscope images of breast tissue were analyzed in order to teach computer to recognize malignancy; 85 percent accuracy rate was achieved. Credit: KTUA team

Updated on:April 14,2024 20

Researchers develop new marker for cancer cell motility

by Leipzig UniversityTwo aggregate states of cancer cell clusters. In blue: densely packed, more rounded cancer cells jam together and cannot move, reducing the risk of metastasis. In green: more

Updated on: February 18,2024 12

Researchers develop new marker for cancer cell motility

by Leipzig UniversityTwo aggregate states of cancer cell clusters. In blue: densely packed, more rounded cancer cells jam together and cannot move, reducing the risk of metastasis. In green: more

Updated on:February 18,2024 12

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of

Updated on: March 30,2024 0

Researchers determine oral bacteria accelerate pancreatic cancer development in mice

by Hebrew University of JerusalemPancreas sections from control and P.gingivalis-infected mice. Control mouse showing a small pre-cancerous lesion (marked in yellow). Credit: Hebrew University of

Updated on:March 30,2024 0

Team identifies the cells responsible for colon cancer relapse

by Institute for Research in Biomedicine (IRB Barcelona)Colorectal cancer organoids, edited to express a tdTomato reporter in cells with high Epithelial membrane protein 1 (Emp1) expression, were

Updated on: February 03,2024 14

Team identifies the cells responsible for colon cancer relapse

by Institute for Research in Biomedicine (IRB Barcelona)Colorectal cancer organoids, edited to express a tdTomato reporter in cells with high Epithelial membrane protein 1 (Emp1) expression, were

Updated on:February 03,2024 14

Blocking glycogen, a key energy source, could slow or prevent ovarian cancer spread

by University of Chicago Medical CenterPathways of early (proliferation) and late (proliferation, invasion and widespread) metastasis. Credit: Study authors working withCell MetabolismIn ne

Updated on: April 01,2024 11

Blocking glycogen, a key energy source, could slow or prevent ovarian cancer spread

by University of Chicago Medical CenterPathways of early (proliferation) and late (proliferation, invasion and widespread) metastasis. Credit: Study authors working withCell MetabolismIn ne

Updated on:April 01,2024 11

Using a seaweed sugar to trigger immune responses that suppress melanomas

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Immunother

Updated on: February 03,2024 10

Using a seaweed sugar to trigger immune responses that suppress melanomas

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Immunother

Updated on:February 03,2024 10

Newly identified personalized immunotherapy combination treats an aggressive form of advanced prostate cancer

byUniversity of Chicago Medical CenterCredit: Unsplash/CC0 Public DomainImmunotherapies have been successful in treating many cancer conditions; however, not much success has yet been achieved i

Updated on: January 13,2024 16

Newly identified personalized immunotherapy combination treats an aggressive form of advanced prostate cancer

byUniversity of Chicago Medical CenterCredit: Unsplash/CC0 Public DomainImmunotherapies have been successful in treating many cancer conditions; however, not much success has yet been achieved i

Updated on:January 13,2024 16

COVID reforms in cancer care and research could have long-term benefits

by King's College LondonCredit: Unsplash/CC0 Public DomainA new review led by Professor James Spicer considers the reforms in cancer care and research made due to the pandemic, arguing that s

Updated on: January 29,2024 10

COVID reforms in cancer care and research could have long-term benefits

by King's College LondonCredit: Unsplash/CC0 Public DomainA new review led by Professor James Spicer considers the reforms in cancer care and research made due to the pandemic, arguing that s

Updated on:January 29,2024 10

FAAH inhibition ameliorates murine breast cancer: Study

by Impact Journals LLCAn overview of the endocannabinoid pathway and molecules tested in this study. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28534A new research paper titled &quo

Updated on: May 11,2024 8

FAAH inhibition ameliorates murine breast cancer: Study

by Impact Journals LLCAn overview of the endocannabinoid pathway and molecules tested in this study. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28534A new research paper titled &quo

Updated on:May 11,2024 8

Potent results from a new immune treatment seen in patients with hard-to-treat blood cancers

by Peter MacCallum Cancer CentreCredit: Pixabay/CC0 Public DomainAll patients in the Phase I / II clinical trial of glofitamab had Diffuse Large B-Cell Lymphoma (DLBCL) and their cancer had relapsed o

Updated on: January 29,2024 18

Potent results from a new immune treatment seen in patients with hard-to-treat blood cancers

by Peter MacCallum Cancer CentreCredit: Pixabay/CC0 Public DomainAll patients in the Phase I / II clinical trial of glofitamab had Diffuse Large B-Cell Lymphoma (DLBCL) and their cancer had relapsed o

Updated on:January 29,2024 18