AZD1390 with radiotherapy shows manageable safety profile and preliminary efficacy for patients with glioblastoma

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAZD1390, an ataxia telangiectasia mutant (ATM) kinase inhibitor, demonstrated a manageable safety profile in both recur

Updated on: April 28,2024

AZD1390 with radiotherapy shows manageable safety profile and preliminary efficacy for patients with glioblastoma

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAZD1390, an ataxia telangiectasia mutant (ATM) kinase inhibitor, demonstrated a manageable safety profile in both recur

Updated on:April 28,2024

Research reveals Orkney cancer gene link—now testing will take place

byUniversity of AberdeenOutline pedigree of two kindreds (A and B) from the ORCADES study. Filled circles are breast or ovarian cancers, red outlines are sequenced V1736A carriers, dotted red ou

Updated on: January 16,2024

Research reveals Orkney cancer gene link—now testing will take place

byUniversity of AberdeenOutline pedigree of two kindreds (A and B) from the ORCADES study. Filled circles are breast or ovarian cancers, red outlines are sequenced V1736A carriers, dotted red ou

Updated on:January 16,2024

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on: May 09,2024

Primary pancreatic organoid tumor models for high-throughput phenotypic drug screening

by SLAS (Society for Laboratory Automation and Screening)A Z-stack image was obtained after staining nuclei with Hoechst using confocal microscopy at 5 micron intervals and then assembled using ImageJ

Updated on:May 09,2024

A new targeted treatment shows promise for select patients with stomach cancer

byWeill Cornell Medical CollegeCredit: Pixabay/CC0 Public DomainAn international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, has found tha

Updated on: January 29,2024

A new targeted treatment shows promise for select patients with stomach cancer

byWeill Cornell Medical CollegeCredit: Pixabay/CC0 Public DomainAn international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, has found tha

Updated on:January 29,2024

Study shows 'feasibility' of ending specialist follow-up in patients with low-risk chronic lymphocytic leukemia

by American Society of HematologyCredit: CC0 Public DomainA study published inBlood Advancesshowed that among patients in Denmark who had slow-growing chronic lymphocytic leukemia (CL

Updated on: April 06,2024

Study shows 'feasibility' of ending specialist follow-up in patients with low-risk chronic lymphocytic leukemia

by American Society of HematologyCredit: CC0 Public DomainA study published inBlood Advancesshowed that among patients in Denmark who had slow-growing chronic lymphocytic leukemia (CL

Updated on:April 06,2024

Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on: January 22,2024

Rethinking the protein inhibitor approach to cancer therapy

byStony Brook UniversityTwo-step strategy for repeatable site-specific gene circuit integration.a, Network diagram of regulatory interactions and phenotypic impacts for native and ectopic

Updated on:January 22,2024

Experts explain treatment options for a common cancer complication

byThe Endocrine SocietyOsteoclast formation, activity, and pharmacologic inhibition. (A) Osteoclasts develop from osteoclast precursor cells when receptor activator of nuclear factor κ B (RANK)

Updated on: January 22,2024

Experts explain treatment options for a common cancer complication

byThe Endocrine SocietyOsteoclast formation, activity, and pharmacologic inhibition. (A) Osteoclasts develop from osteoclast precursor cells when receptor activator of nuclear factor κ B (RANK)

Updated on:January 22,2024

Protein discovery sparks treatment hope for aggressive cancer

by Walter and Eliza Hall Institute of Medical ResearchTreating acute lymphoblastic leukaemia cells with the drug CX-5461 disrupts the nucleolar ribosome machinery shown by the fibrillarin protein

Updated on: March 20,2024

Protein discovery sparks treatment hope for aggressive cancer

by Walter and Eliza Hall Institute of Medical ResearchTreating acute lymphoblastic leukaemia cells with the drug CX-5461 disrupts the nucleolar ribosome machinery shown by the fibrillarin protein

Updated on:March 20,2024

New drug targets for BRCA-driven cancer uncovered

by Brigham and Women's HospitalCredit: CC0 Public DomainBRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes h

Updated on: March 30,2024

New drug targets for BRCA-driven cancer uncovered

by Brigham and Women's HospitalCredit: CC0 Public DomainBRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes h

Updated on:March 30,2024

Detecting breast cancer earlier with 3D X-rays

by Werner Siefer,ETH ZurichComparison of conventional computed tomography with the new GI-CT images. The increased image quality of the GI-CT is particularly evident for small features (indicate

Updated on: February 23,2024

Detecting breast cancer earlier with 3D X-rays

by Werner Siefer,ETH ZurichComparison of conventional computed tomography with the new GI-CT images. The increased image quality of the GI-CT is particularly evident for small features (indicate

Updated on:February 23,2024

Study finds non-Hodgkins lymphoma treatment also targets related forms of lymphoma

by Hudson Institute of Medical ResearchHelicobacter-infected Nlrc5mø-KOmice develop precursor lesions to gastric B-cell MALT lymphoma. Representative H&E-stained sections of gastric tis

Updated on: February 23,2024

Study finds non-Hodgkins lymphoma treatment also targets related forms of lymphoma

by Hudson Institute of Medical ResearchHelicobacter-infected Nlrc5mø-KOmice develop precursor lesions to gastric B-cell MALT lymphoma. Representative H&E-stained sections of gastric tis

Updated on:February 23,2024

The virtual cancer patient

by Technische Universitat DarmstadtIn the laboratory: Professor Heinz Koeppl (left) and his research associate Jascha Diemer. Credit: Katrin BinnerNo two cancers are the same. Each type of leukae

Updated on: March 01,2024

The virtual cancer patient

by Technische Universitat DarmstadtIn the laboratory: Professor Heinz Koeppl (left) and his research associate Jascha Diemer. Credit: Katrin BinnerNo two cancers are the same. Each type of leukae

Updated on:March 01,2024