Stem cell reserves found in the stomach have implications for the genesis of gastric cancer

by Agency for Science, Technology and Research (A*STAR), SingaporeThe study revealed that Lgr5-expressing chief cells in the corpus glands can become gastric cancer precursors. Credit: Springer N

Updated on: April 22,2024 10

Stem cell reserves found in the stomach have implications for the genesis of gastric cancer

by Agency for Science, Technology and Research (A*STAR), SingaporeThe study revealed that Lgr5-expressing chief cells in the corpus glands can become gastric cancer precursors. Credit: Springer N

Updated on:April 22,2024 10

From eye drops to potential leukaemia treatment

by Wellcome Trust Sanger InstituteA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaAn active ingredient

Updated on: March 12,2024 10

From eye drops to potential leukaemia treatment

by Wellcome Trust Sanger InstituteA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaAn active ingredient

Updated on:March 12,2024 10

Use of MMR deficiency testing in younger CRC patients is low

(HealthDay)—Fewer than half of younger adults with colorectal cancer (CRC) undergo mismatch repair (MMR) deficiency of DNA testing, according to a study published online Nov. 9 inJAMA Oncology.T

Updated on: April 22,2024 14

Use of MMR deficiency testing in younger CRC patients is low

(HealthDay)—Fewer than half of younger adults with colorectal cancer (CRC) undergo mismatch repair (MMR) deficiency of DNA testing, according to a study published online Nov. 9 inJAMA Oncology.T

Updated on:April 22,2024 14

Deep learning algorithm may streamline lung cancer radiotherapy treatment

byBrigham and Women's HospitalCredit: Unsplash/CC0 Public DomainLung cancer, the most common cancer worldwide, is targeted with radiation therapy (RT) in nearly one-half of cases. RT plannin

Updated on: January 04,2024 9

Deep learning algorithm may streamline lung cancer radiotherapy treatment

byBrigham and Women's HospitalCredit: Unsplash/CC0 Public DomainLung cancer, the most common cancer worldwide, is targeted with radiation therapy (RT) in nearly one-half of cases. RT plannin

Updated on:January 04,2024 9

A multiplex assay to assess activated p300/CBP in circulating prostate tumor cells

by Impact Journals LLCOptimization of circulating tumor cells (CTC) staining and validation of p300 activity. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28477A new research paper wa

Updated on: February 18,2024 19

A multiplex assay to assess activated p300/CBP in circulating prostate tumor cells

by Impact Journals LLCOptimization of circulating tumor cells (CTC) staining and validation of p300 activity. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28477A new research paper wa

Updated on:February 18,2024 19

Substance in the blood is found to increase as early as two years before diagnosis of pancreatic cancer

by Ola Nilsson,Umea UniversitySeparating future PDAC cases from controls in pre-diagnostic and diagnostic samples with a cross-sectional analysis. Box plots of the individual marker concentratio

Updated on: February 01,2024 18

Substance in the blood is found to increase as early as two years before diagnosis of pancreatic cancer

by Ola Nilsson,Umea UniversitySeparating future PDAC cases from controls in pre-diagnostic and diagnostic samples with a cross-sectional analysis. Box plots of the individual marker concentratio

Updated on:February 01,2024 18

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on: January 12,2024 8

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on:January 12,2024 8

Clinical trial: Addition of atezolizumab to standard care does not improve limited-stage small cell lung cancer survival

by NRG OncologyCredit: Unsplash/CC0 Public DomainThe addition of the cancer immunotherapy drug atezolizumab to the standard of care concurrent chemoradiation (cCRT) did not improve overall survival fo

Updated on: October 21,2024 0

Clinical trial: Addition of atezolizumab to standard care does not improve limited-stage small cell lung cancer survival

by NRG OncologyCredit: Unsplash/CC0 Public DomainThe addition of the cancer immunotherapy drug atezolizumab to the standard of care concurrent chemoradiation (cCRT) did not improve overall survival fo

Updated on:October 21,2024 0

Subtypes of fibroblasts associated with skin cancer could lead to novel immunotherapies

byMedical University of ViennaSchematic summary of spatial distribution of distinct CAF subsets in human skin cancer. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5390

Updated on: December 01,2024 0

Subtypes of fibroblasts associated with skin cancer could lead to novel immunotherapies

byMedical University of ViennaSchematic summary of spatial distribution of distinct CAF subsets in human skin cancer. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5390

Updated on:December 01,2024 0

A CAR T cell therapy for advanced ovarian cancer developed

by City of Hope National Medical CenterMembrane-bound IL-12 engineered TAG72-CAR T cells induce higher IFNγ, T-cell expansion, and anti-tumor activity in vitro.a–cTumor cell killing o

Updated on: February 18,2024 10

A CAR T cell therapy for advanced ovarian cancer developed

by City of Hope National Medical CenterMembrane-bound IL-12 engineered TAG72-CAR T cells induce higher IFNγ, T-cell expansion, and anti-tumor activity in vitro.a–cTumor cell killing o

Updated on:February 18,2024 10

Team identifies the cells responsible for colon cancer relapse

by Institute for Research in Biomedicine (IRB Barcelona)Colorectal cancer organoids, edited to express a tdTomato reporter in cells with high Epithelial membrane protein 1 (Emp1) expression, were

Updated on: February 03,2024 14

Team identifies the cells responsible for colon cancer relapse

by Institute for Research in Biomedicine (IRB Barcelona)Colorectal cancer organoids, edited to express a tdTomato reporter in cells with high Epithelial membrane protein 1 (Emp1) expression, were

Updated on:February 03,2024 14

Combination therapy overcomes BET inhibitor resistance, shows study

bySt. Jude Children's Research HospitalStudy first author Shaela Fields (Wright), from the lab of Chunliang, Li, PhD, St. Jude Department of Tumor Cell Biology, led research to understand BE

Updated on: January 16,2024 12

Combination therapy overcomes BET inhibitor resistance, shows study

bySt. Jude Children's Research HospitalStudy first author Shaela Fields (Wright), from the lab of Chunliang, Li, PhD, St. Jude Department of Tumor Cell Biology, led research to understand BE

Updated on:January 16,2024 12