What Comes after NCI-MATCH? NCI’s New Precision Medicine Cancer Trials

SubscribeDecember 6, 2023, by James H. Doroshow, M.D.Findings from NCI-MATCH and its successor trials will help oncologists implement precision medicine in everyday patient care.Credit: iStockMore tha

Updated on: December 19,2023 45

What Comes after NCI-MATCH? NCI’s New Precision Medicine Cancer Trials

SubscribeDecember 6, 2023, by James H. Doroshow, M.D.Findings from NCI-MATCH and its successor trials will help oncologists implement precision medicine in everyday patient care.Credit: iStockMore tha

Updated on:December 19,2023 45

HER2+ early breast cancers where shorter-course trastuzumab could be an option

byEuropean Society for Medical OncologyCredit: European Society for Medical OncologyWomen with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower r

Updated on: December 18,2023 17

HER2+ early breast cancers where shorter-course trastuzumab could be an option

byEuropean Society for Medical OncologyCredit: European Society for Medical OncologyWomen with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower r

Updated on:December 18,2023 17

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on: December 21,2023 7

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on:December 21,2023 7

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet

Updated on: October 30,2023 29

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet

Updated on:October 30,2023 29

Allogeneic HCT after primary induction failure beneficial in leukemia

by Elana GotkineFor patients with acute myeloid leukemia (AML), immediate allogeneic hematopoietic stem cell transplantation (HCT) after primary induction failure (PIF) offers long-term survival benef

Updated on: December 26,2023 16

Allogeneic HCT after primary induction failure beneficial in leukemia

by Elana GotkineFor patients with acute myeloid leukemia (AML), immediate allogeneic hematopoietic stem cell transplantation (HCT) after primary induction failure (PIF) offers long-term survival benef

Updated on:December 26,2023 16

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

In a study published inCancer Discovery, researchers from Canada tested the use of a multimodal liquid biopsy assay based on cell-free DNA (cfDNA) for early cancer detection in patients with Li-

Updated on: October 30,2023 22

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

In a study published inCancer Discovery, researchers from Canada tested the use of a multimodal liquid biopsy assay based on cell-free DNA (cfDNA) for early cancer detection in patients with Li-

Updated on:October 30,2023 22

Strategy could remove metastatic traits and drug resistance from lung cancer cells

byThe Korea Advanced Institute of Science and Technology (KAIST)Figure 1. Construction of the mathematical model of the regulatory network to represent the EMT phenotype based on the interaction

Updated on: December 19,2023 10

Strategy could remove metastatic traits and drug resistance from lung cancer cells

byThe Korea Advanced Institute of Science and Technology (KAIST)Figure 1. Construction of the mathematical model of the regulatory network to represent the EMT phenotype based on the interaction

Updated on:December 19,2023 10

Stem cells establish contacts with nerves in tissue regeneration and cancer progression

Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demons

Updated on: October 28,2023 16

Stem cells establish contacts with nerves in tissue regeneration and cancer progression

Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demons

Updated on:October 28,2023 16

Australian research shows rates of obesity-related cancers quadrupled in a generation

by Cancer CouncilCredit: CC0 Public DomainNew research by the Daffodil Center, a joint venture of Cancer Council NSW and the University of Sydney, shows the rate of obesity-related cancers in Australi

Updated on: December 19,2023 12

Australian research shows rates of obesity-related cancers quadrupled in a generation

by Cancer CouncilCredit: CC0 Public DomainNew research by the Daffodil Center, a joint venture of Cancer Council NSW and the University of Sydney, shows the rate of obesity-related cancers in Australi

Updated on:December 19,2023 12

Study shows older age and smoking most important risk factors for developing any cancer

byAmerican Cancer SocietyCredit: Unsplash/CC0 Public DomainA new large study led by researchers at the American Cancer Society (ACS) shows older age and smoking are the two most important risk f

Updated on: December 18,2023 23

Study shows older age and smoking most important risk factors for developing any cancer

byAmerican Cancer SocietyCredit: Unsplash/CC0 Public DomainA new large study led by researchers at the American Cancer Society (ACS) shows older age and smoking are the two most important risk f

Updated on:December 18,2023 23

Scientists discover how air pollution triggers lung cancer

Credit: Pixabay/CC0 Public DomainScientists said Saturday they had identified the mechanism through which air pollution triggers lung cancer in non-smokers, a discovery one expert hailed as "an i

Updated on: December 27,2023 10

Scientists discover how air pollution triggers lung cancer

Credit: Pixabay/CC0 Public DomainScientists said Saturday they had identified the mechanism through which air pollution triggers lung cancer in non-smokers, a discovery one expert hailed as "an i

Updated on:December 27,2023 10

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

byGeorgetown University Medical CenterCredit: Unsplash/CC0 Public DomainWhile it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developin

Updated on: December 19,2023 10

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

byGeorgetown University Medical CenterCredit: Unsplash/CC0 Public DomainWhile it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developin

Updated on:December 19,2023 10