'Hard to lose' mutations in tumors may predict response to immunotherapy

byJohns Hopkins University School of MedicineThe figure shows the interactions between immune cells (white) and tumor cells harboring persistent mutations (red) in the context of immunotherapy (

Updated on: January 22,2024

'Hard to lose' mutations in tumors may predict response to immunotherapy

byJohns Hopkins University School of MedicineThe figure shows the interactions between immune cells (white) and tumor cells harboring persistent mutations (red) in the context of immunotherapy (

Updated on:January 22,2024

Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on: February 18,2024

Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on:February 18,2024

Race could affect outcomes in head and neck cancers

by Cara Murez HealthDay ReporterBlack patients with head and neck cancers have twice the death rates of white patients, and a new study suggests race itself underlies those differences."What is u

Updated on: January 22,2024

Race could affect outcomes in head and neck cancers

by Cara Murez HealthDay ReporterBlack patients with head and neck cancers have twice the death rates of white patients, and a new study suggests race itself underlies those differences."What is u

Updated on:January 22,2024

Study suggests chromosomal errors may hinder some aggressive tumors

by Julie Vera,Mayo ClinicGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.100937Chromosomal errors are a hallmark of cancer cells. Defects in the geno

Updated on: January 22,2024

Study suggests chromosomal errors may hinder some aggressive tumors

by Julie Vera,Mayo ClinicGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.100937Chromosomal errors are a hallmark of cancer cells. Defects in the geno

Updated on:January 22,2024

Discovery may lead to natural ent-kaurane diterpenoid for NK-based tumor immunotherapy

by Chinese Academy of SciencesCredit: KIBAs early responders in the surveillance of malignant cells, natural killer (NK) cells play a significant role in the control of transformed cells at the t

Updated on: April 14,2024

Discovery may lead to natural ent-kaurane diterpenoid for NK-based tumor immunotherapy

by Chinese Academy of SciencesCredit: KIBAs early responders in the surveillance of malignant cells, natural killer (NK) cells play a significant role in the control of transformed cells at the t

Updated on:April 14,2024

Q&A: Researchers discuss identifying potential new protein targets for melanoma therapeutics

byBrigham and Women’s HospitalGlobal characterization of the melanoma samples and their expression of CEACAM1. Credit:Communications Medicine(2024). DOI: 10.1038/s43856-024-00525-8Yu

Updated on: August 28,2024

Q&A: Researchers discuss identifying potential new protein targets for melanoma therapeutics

byBrigham and Women’s HospitalGlobal characterization of the melanoma samples and their expression of CEACAM1. Credit:Communications Medicine(2024). DOI: 10.1038/s43856-024-00525-8Yu

Updated on:August 28,2024

Gray hair and wrinkles at an early age lead researchers to potential new treatment for rare cancer

by University of CopenhagenSchematic representation of the PandaOmics application for a rapid biomarker discovery and target characterization in cancer. Gene expression signatures have been exami

Updated on: February 18,2024

Gray hair and wrinkles at an early age lead researchers to potential new treatment for rare cancer

by University of CopenhagenSchematic representation of the PandaOmics application for a rapid biomarker discovery and target characterization in cancer. Gene expression signatures have been exami

Updated on:February 18,2024

Cancer cell repopulation after therapy: Study explores the mechanism

by Impact Journals LLCPresumed models of tumor cell repopulation after escaping chemoradiation. Credit: 2023 Prakash and TelleriaThe past two decades have brought great progress in the treatment of ca

Updated on: January 30,2024

Cancer cell repopulation after therapy: Study explores the mechanism

by Impact Journals LLCPresumed models of tumor cell repopulation after escaping chemoradiation. Credit: 2023 Prakash and TelleriaThe past two decades have brought great progress in the treatment of ca

Updated on:January 30,2024

Researchers show how a tumor cell's location and environment affect its identity

by National Institutes of HealthDifferences in cell layers' fluorescent-dye uptake in a model of high-grade serous ovarian cancer. Credit: David B. Morse.Using 3D models of ovarian cancer tum

Updated on: January 30,2024

Researchers show how a tumor cell's location and environment affect its identity

by National Institutes of HealthDifferences in cell layers' fluorescent-dye uptake in a model of high-grade serous ovarian cancer. Credit: David B. Morse.Using 3D models of ovarian cancer tum

Updated on:January 30,2024

Study identifies prostate cancer-related disparities between Indigenous and non-Indigenous men

by WileyCredit: CC0 Public DomainIndigenous Peoples in Canada have higher illness rates and lower life expectancies than non-Indigenous Canadians. A new study reveals that Indigenous men in the c

Updated on: January 30,2024

Study identifies prostate cancer-related disparities between Indigenous and non-Indigenous men

by WileyCredit: CC0 Public DomainIndigenous Peoples in Canada have higher illness rates and lower life expectancies than non-Indigenous Canadians. A new study reveals that Indigenous men in the c

Updated on:January 30,2024

Treating tumors with engineered dendritic cells

by Ecole Polytechnique Federale de LausanneCerebral tumor (glioma) of a mouse. Credit: EPFL / Michele De Palma—CC-BY-SA 4.0Cancer biologists at EPFL, UNIGE, and the German Cancer Research Center

Updated on: May 11,2024

Treating tumors with engineered dendritic cells

by Ecole Polytechnique Federale de LausanneCerebral tumor (glioma) of a mouse. Credit: EPFL / Michele De Palma—CC-BY-SA 4.0Cancer biologists at EPFL, UNIGE, and the German Cancer Research Center

Updated on:May 11,2024

Exploring ferroptosis and its implications in lung cancer

by Cactus CommunicationsEven with advances in diagnosis and treatments, the survival rate of patients with lung cancer, remains to be low. Ferroptosis is a type of iron-dependent programmed cell death

Updated on: March 30,2024

Exploring ferroptosis and its implications in lung cancer

by Cactus CommunicationsEven with advances in diagnosis and treatments, the survival rate of patients with lung cancer, remains to be low. Ferroptosis is a type of iron-dependent programmed cell death

Updated on:March 30,2024