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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Research reveals Orkney cancer gene link—now testing will take place

Research reveals Orkney cancer gene link—now testing will take place

byUniversity of AberdeenOutline pedigree of two kindreds (A and B) from the ORCADES study. Filled circles are breast or ovarian cancers, red outlines are sequenced V1736A carriers, dotted red ou

Research reveals Orkney cancer gene link—now testing will take place

byUniversity of AberdeenOutline pedigree of two kindreds (A and B) from the ORCADES study. Filled circles are breast or ovarian cancers, red outlines are sequenced V1736A carriers, dotted red ou
Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor

Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor

by St. Jude Children's Research HospitalElizabeth Stewart, M.D., and Hong Wang, Ph.D. of St. Jude Children's Research Hospital. Credit: St. Jude Children's Research HospitalSt. Jude C

Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor

by St. Jude Children's Research HospitalElizabeth Stewart, M.D., and Hong Wang, Ph.D. of St. Jude Children's Research Hospital. Credit: St. Jude Children's Research HospitalSt. Jude C
Researchers identify a regulator of breast cancer development

Researchers identify a regulator of breast cancer development

by UT Southwestern Medical CenterBreast cancer stem cells (BCSCs) are responsible for breast carcinogenesis. Researchers' work reveals potential targets for killing BCSCs to prevent breast tu

Researchers identify a regulator of breast cancer development

by UT Southwestern Medical CenterBreast cancer stem cells (BCSCs) are responsible for breast carcinogenesis. Researchers' work reveals potential targets for killing BCSCs to prevent breast tu
AI improving digestive cancer diagnosis, but data-sharing obstacles remain

AI improving digestive cancer diagnosis, but data-sharing obstacles remain

by Health Data ScienceThe AI analysis workflow in digestive system neoplasms. SVM, support vector machine; LASSO, the least absolute shrinkage and selection operator; LN, lymph node; ROC, receiver ope

AI improving digestive cancer diagnosis, but data-sharing obstacles remain

by Health Data ScienceThe AI analysis workflow in digestive system neoplasms. SVM, support vector machine; LASSO, the least absolute shrinkage and selection operator; LN, lymph node; ROC, receiver ope
Breast implant illness uncommon cause of revision surgery

Breast implant illness uncommon cause of revision surgery

Among women with silicone breast implants, breast implant illness (BII) is an uncommon indication for revision, according to a study published online Oct. 7 inJAMA Network Open.Annemiek S. Lieff

Breast implant illness uncommon cause of revision surgery

Among women with silicone breast implants, breast implant illness (BII) is an uncommon indication for revision, according to a study published online Oct. 7 inJAMA Network Open.Annemiek S. Lieff
Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b

Preclinical study shows promise of systemic targeted therapy in a rare form of cancer

byVall d'Hebron Institute of OncologyTreatment with BRAF inhibitors reduces tumor cell proliferation in subcutaneous BRAFV600EPMP-PDX tumors without impacting in apoptosis. a–d) Mice b
New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t

New AI-based biomarker can help predict immunotherapy response for patients with lung cancer

byEmory UniversityResponder tumor to ICI has less tortuous vessel branches compared to nonresponder. (A and B) CT scans of a responder and nonresponder to IO with corresponding 3D rendering of t
Cancer drug cooperation could save 1.5 mn lives a year: researchers

Cancer drug cooperation could save 1.5 mn lives a year: researchers

Credit: Pixabay/CC0 Public DomainAround 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.The figure was based

Cancer drug cooperation could save 1.5 mn lives a year: researchers

Credit: Pixabay/CC0 Public DomainAround 1.5 million lives could be saved every year if the world worked together to more swiftly approve new cancer drugs, researchers said Tuesday.The figure was based
Newly identified genetic markers classify previously undetermined glioblastoma tumors

Newly identified genetic markers classify previously undetermined glioblastoma tumors

by Duke UniversitySMARCAL1 mutations identified in this study were found to be involved in how cancer cells become immortal by keeping their telomeres long through a process known as alternative

Newly identified genetic markers classify previously undetermined glioblastoma tumors

by Duke UniversitySMARCAL1 mutations identified in this study were found to be involved in how cancer cells become immortal by keeping their telomeres long through a process known as alternative
Q&A: Researchers discuss identifying potential new protein targets for melanoma therapeutics

Q&A: Researchers discuss identifying potential new protein targets for melanoma therapeutics

byBrigham and Women’s HospitalGlobal characterization of the melanoma samples and their expression of CEACAM1. Credit:Communications Medicine(2024). DOI: 10.1038/s43856-024-00525-8Yu

Q&A: Researchers discuss identifying potential new protein targets for melanoma therapeutics

byBrigham and Women’s HospitalGlobal characterization of the melanoma samples and their expression of CEACAM1. Credit:Communications Medicine(2024). DOI: 10.1038/s43856-024-00525-8Yu
Oncoprotein activity increases prostate cancer progression, finds study

Oncoprotein activity increases prostate cancer progression, finds study

by Melissa Rohman,Northwestern UniversityMYC activation in neoplastic cells reprograms the prostate TME. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-51450-2Investigat

Oncoprotein activity increases prostate cancer progression, finds study

by Melissa Rohman,Northwestern UniversityMYC activation in neoplastic cells reprograms the prostate TME. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-51450-2Investigat
Genetic ancestry and social environment may influence how aggressive breast cancer is in Black women

Genetic ancestry and social environment may influence how aggressive breast cancer is in Black women

by Rutgers Cancer Institute of New JerseyKaplan-Meier Survival Curves for All-Cause Mortality by Quartiles (Q) of African Ancestry and Neighborhood Socioeconomic Status (nSES) in 1,575 Black Women wit

Genetic ancestry and social environment may influence how aggressive breast cancer is in Black women

by Rutgers Cancer Institute of New JerseyKaplan-Meier Survival Curves for All-Cause Mortality by Quartiles (Q) of African Ancestry and Neighborhood Socioeconomic Status (nSES) in 1,575 Black Women wit