Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on: April 07,2024 12

Resetting the epigenetic balance for cancer therapy

by Will Doss,Northwestern UniversityKiller T cells surround a cancer cell. Credit: NIHThough mutations in a gene called MLL3 are common across many types of cancers, their relationship to the de

Updated on:April 07,2024 12

Unique approach to treatment of rare and aggressive blood cancers

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainA unique approach to targeting the abnormal T-cells that cause T-cell lymphomas could offer hope to patients with the aggressive and dif

Updated on: April 10,2024 15

Unique approach to treatment of rare and aggressive blood cancers

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainA unique approach to targeting the abnormal T-cells that cause T-cell lymphomas could offer hope to patients with the aggressive and dif

Updated on:April 10,2024 15

Newly identified genetic markers classify previously undetermined glioblastoma tumors

by Duke UniversitySMARCAL1 mutations identified in this study were found to be involved in how cancer cells become immortal by keeping their telomeres long through a process known as alternative

Updated on: March 01,2024 12

Newly identified genetic markers classify previously undetermined glioblastoma tumors

by Duke UniversitySMARCAL1 mutations identified in this study were found to be involved in how cancer cells become immortal by keeping their telomeres long through a process known as alternative

Updated on:March 01,2024 12

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on: February 18,2024 14

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on:February 18,2024 14

Researchers identify a possible therapeutic target for Kennedy´s disease and prostate cancer

by Institute for Research in Biomedicine (IRB Barcelona)Interaction of the androgen receptor and chaperone Hsp70 (in red) inside the cell. Blue indicates cell nuclei.Xavier Salvatella, IRB Barcel

Updated on: June 06,2024 5

Researchers identify a possible therapeutic target for Kennedy´s disease and prostate cancer

by Institute for Research in Biomedicine (IRB Barcelona)Interaction of the androgen receptor and chaperone Hsp70 (in red) inside the cell. Blue indicates cell nuclei.Xavier Salvatella, IRB Barcel

Updated on:June 06,2024 5

Cancer cell repopulation after therapy: Study explores the mechanism

by Impact Journals LLCPresumed models of tumor cell repopulation after escaping chemoradiation. Credit: 2023 Prakash and TelleriaThe past two decades have brought great progress in the treatment of ca

Updated on: January 30,2024 16

Cancer cell repopulation after therapy: Study explores the mechanism

by Impact Journals LLCPresumed models of tumor cell repopulation after escaping chemoradiation. Credit: 2023 Prakash and TelleriaThe past two decades have brought great progress in the treatment of ca

Updated on:January 30,2024 16

Breast cancer study confirms importance of multigenerational family data to assess risk

by Columbia University's Mailman School of Public HealthMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainA team of researchers led by Columbia

Updated on: March 01,2024 14

Breast cancer study confirms importance of multigenerational family data to assess risk

by Columbia University's Mailman School of Public HealthMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainA team of researchers led by Columbia

Updated on:March 01,2024 14

Young cancer survivors face elevated risk of developing cardiovascular disease, but factors that may impact this risk

byWileyCredit: Pixabay/CC0 Public DomainAdolescent and young adult (AYA) cancer survivors are at risk of experiencing treatment-related effects later in life, including damage to the heart. New

Updated on: January 02,2024 9

Young cancer survivors face elevated risk of developing cardiovascular disease, but factors that may impact this risk

byWileyCredit: Pixabay/CC0 Public DomainAdolescent and young adult (AYA) cancer survivors are at risk of experiencing treatment-related effects later in life, including damage to the heart. New

Updated on:January 02,2024 9

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on: January 02,2024 9

Potential melanoma target bypasses therapeutic resistance to immune checkpoint blockers

by Jeff Hansen,University of Alabama at BirminghamConstitutive activation of JAK1/2 in IFNγR1KOmelanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine ki

Updated on:January 02,2024 9

One dose of radiotherapy as effective as five doses for cancer in the spine

by University College LondonCredit: CC0 Public DomainA single dose of radiotherapy is as "effective" as five doses for end-of-life cancer patients suffering with painful spinal canal co

Updated on: March 08,2024 18

One dose of radiotherapy as effective as five doses for cancer in the spine

by University College LondonCredit: CC0 Public DomainA single dose of radiotherapy is as "effective" as five doses for end-of-life cancer patients suffering with painful spinal canal co

Updated on:March 08,2024 18

Team studies association between tumor mutations and meningioma recurrence in Grade I/II disease

by Impact JournalsAdjusted progression-free survival hazard ratios for genes examined. Credit: 2022 Dullea et al.A new research paper titled "Association between tumor mutations and meningioma re

Updated on: February 03,2024 20

Team studies association between tumor mutations and meningioma recurrence in Grade I/II disease

by Impact JournalsAdjusted progression-free survival hazard ratios for genes examined. Credit: 2022 Dullea et al.A new research paper titled "Association between tumor mutations and meningioma re

Updated on:February 03,2024 20

New possibilities for treating intractable brain tumors unveiled

New possibilities for treating intractable brain tumors unveiledbyThe Korea Advanced Institute of Science and Technology (KAIST)Overview of the study on the enhanced response to anti-PD-1 therap

Updated on: December 01,2024 0

New possibilities for treating intractable brain tumors unveiled

New possibilities for treating intractable brain tumors unveiledbyThe Korea Advanced Institute of Science and Technology (KAIST)Overview of the study on the enhanced response to anti-PD-1 therap

Updated on:December 01,2024 0