Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase

by SLAS (Society for Laboratory Automation and Screening)ALDOA catalyzes the reversible aldol cleavage of fructose-1,6-bisphosphate (F-1,6-BP) into D-Glyceraldehyde-3-phosphate (GAP) and dihydroxyacet

Updated on: March 01,2024

Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase

by SLAS (Society for Laboratory Automation and Screening)ALDOA catalyzes the reversible aldol cleavage of fructose-1,6-bisphosphate (F-1,6-BP) into D-Glyceraldehyde-3-phosphate (GAP) and dihydroxyacet

Updated on:March 01,2024

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Updated on: February 18,2024

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Updated on:February 18,2024

Dietary supplement helps combat resistance in breast cancer, finds study

byUniversity of BaselCredit: Unsplash/CC0 Public DomainMany cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medicatio

Updated on: January 23,2024

Dietary supplement helps combat resistance in breast cancer, finds study

byUniversity of BaselCredit: Unsplash/CC0 Public DomainMany cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medicatio

Updated on:January 23,2024

Understanding the role of cancer's circular genome in tumor evolution

byQueen Mary, University of LondonOverview of strategies to develop and test rules of ecDNA behavior with mathematical modeling, computer simulations, cell line and patient data. Credit:Na

Updated on: December 28,2023

Understanding the role of cancer's circular genome in tumor evolution

byQueen Mary, University of LondonOverview of strategies to develop and test rules of ecDNA behavior with mathematical modeling, computer simulations, cell line and patient data. Credit:Na

Updated on:December 28,2023

Study identifies five key factors that predict response of cancer patients to immunotherapy

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Unsplash/CC0 Public DomainA team of researchers at IRB Barcelona has identified five independent factors that predict cancer patien

Updated on: September 28,2024

Study identifies five key factors that predict response of cancer patients to immunotherapy

byInstitute for Research in Biomedicine (IRB Barcelona)Credit: Unsplash/CC0 Public DomainA team of researchers at IRB Barcelona has identified five independent factors that predict cancer patien

Updated on:September 28,2024

An unexpected developmental hierarchy in an unusual disease

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesLCH cells from a tumour biopsy, imaged with a confocal microscope. The green staining identifies the actively prolifer

Updated on: April 20,2024

An unexpected developmental hierarchy in an unusual disease

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesLCH cells from a tumour biopsy, imaged with a confocal microscope. The green staining identifies the actively prolifer

Updated on:April 20,2024

Using a seaweed sugar to trigger immune responses that suppress melanomas

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Immunother

Updated on: February 03,2024

Using a seaweed sugar to trigger immune responses that suppress melanomas

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Immunother

Updated on:February 03,2024

Researchers improve classification of pancreatic cancer to better predict patient outcomes

by Katie Sullivan,University of TorontoSangeetha Kalimuthu, an assistant professor of laboratory medicine and pathobiology at U of T and a gastrointestinal pathologist at UHN, is the co-author o

Updated on: June 15,2024

Researchers improve classification of pancreatic cancer to better predict patient outcomes

by Katie Sullivan,University of TorontoSangeetha Kalimuthu, an assistant professor of laboratory medicine and pathobiology at U of T and a gastrointestinal pathologist at UHN, is the co-author o

Updated on:June 15,2024

New tools used to identify childhood cancer genes

by UT Southwestern Medical CenterEmbryonal rhabdomyosarcoma cells. Credit: UT SouthwesternUsing a new computational strategy, researchers at UT Southwestern Medical Center have identified 29 gene

Updated on: May 09,2024

New tools used to identify childhood cancer genes

by UT Southwestern Medical CenterEmbryonal rhabdomyosarcoma cells. Credit: UT SouthwesternUsing a new computational strategy, researchers at UT Southwestern Medical Center have identified 29 gene

Updated on:May 09,2024

Novel inherited variants may raise risk for Hodgkin lymphoma

Novel coding and noncoding gene variants have been identified that may increase the risk for developing Hodgkin lymphoma (HL), according to a study published online Aug. 20 inBlood.Jamie E. Fler

Updated on: January 13,2024

Novel inherited variants may raise risk for Hodgkin lymphoma

Novel coding and noncoding gene variants have been identified that may increase the risk for developing Hodgkin lymphoma (HL), according to a study published online Aug. 20 inBlood.Jamie E. Fler

Updated on:January 13,2024

Tumor matrix profiling gives clues to progression of some lung cancers

byGarvan Institute of Medical ResearchGraphic of lungs and cells. Credit: Thomas Cox/Garvan InstituteScientists at the Garvan Institute of Medical Research have identified molecular profiles of

Updated on: January 22,2024

Tumor matrix profiling gives clues to progression of some lung cancers

byGarvan Institute of Medical ResearchGraphic of lungs and cells. Credit: Thomas Cox/Garvan InstituteScientists at the Garvan Institute of Medical Research have identified molecular profiles of

Updated on:January 22,2024

Study examines hesitation toward potential changes to bowel cancer surveillance

byFlinders UniversityCredit: Pixabay/CC0 Public DomainAs doctors and researchers discuss whether to push recommended bowel cancer colonoscopy surveillance intervals out beyond five years, new re

Updated on: January 22,2024

Study examines hesitation toward potential changes to bowel cancer surveillance

byFlinders UniversityCredit: Pixabay/CC0 Public DomainAs doctors and researchers discuss whether to push recommended bowel cancer colonoscopy surveillance intervals out beyond five years, new re

Updated on:January 22,2024