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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Illuminating tumor cells with dark proteins

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T

Illuminating tumor cells with dark proteins

by Columbia UniversityRibosome roadblock effect: comparing the AMD1 tail sequence, poly(A) and the XBP1 stalling sequence. a–e, Reporter constructs shown on the left were transfected into HEK293T
ACO enrollment ups appropriateness of CA screening

ACO enrollment ups appropriateness of CA screening

(HealthDay)—Enrollment in the Medicare Shared Savings Program (MSSP) Accountable Care Organization (ACO) is associated with a reduction in breast cancer screening and an increase in colorectal cancer

ACO enrollment ups appropriateness of CA screening

(HealthDay)—Enrollment in the Medicare Shared Savings Program (MSSP) Accountable Care Organization (ACO) is associated with a reduction in breast cancer screening and an increase in colorectal cancer
Researchers map the genome of testicular cancer

Researchers map the genome of testicular cancer

by Laura Oleniacz,UNC Lineberger Comprehensive Cancer CenterUNC Lineberger's Katherine Hoadley, PhD. Credit: UNC Lineberger Comprehensive Cancer CenterTesticular germ cell cancer, a disease

Researchers map the genome of testicular cancer

by Laura Oleniacz,UNC Lineberger Comprehensive Cancer CenterUNC Lineberger's Katherine Hoadley, PhD. Credit: UNC Lineberger Comprehensive Cancer CenterTesticular germ cell cancer, a disease
Software program that looks for the most effective drugs helps to personalize cancer treatments

Software program that looks for the most effective drugs helps to personalize cancer treatments

byThe Spanish National Cancer Research CentreGraphical Abstract. Credit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad412Precision medicine seeks to adapt treatments to the char

Software program that looks for the most effective drugs helps to personalize cancer treatments

byThe Spanish National Cancer Research CentreGraphical Abstract. Credit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad412Precision medicine seeks to adapt treatments to the char
Simple test could lead to more personalized treatment of rare ovarian cancer

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl

Simple test could lead to more personalized treatment of rare ovarian cancer

by University of New South WalesKaplan Meier curves of overall survival of ‘high’, ‘medium’ and ‘low’ tertiles of mRNA expression of THSB2 (left) and TAGLN (right) in MOC (n=185). Credit:Cl
Epigenetic drugs in the mission to beat rare cancers

Epigenetic drugs in the mission to beat rare cancers

by Simon Schmitt,Helmholtz Association of German Research CentresViability, SSTR2 protein levels, and [68Ga]Ga-DOTA-TATE uptake of MPC and MTT cells treated with epigenetic drugs; (A) Sequence o

Epigenetic drugs in the mission to beat rare cancers

by Simon Schmitt,Helmholtz Association of German Research CentresViability, SSTR2 protein levels, and [68Ga]Ga-DOTA-TATE uptake of MPC and MTT cells treated with epigenetic drugs; (A) Sequence o
Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven
Scientists discover how satellite RNA leads to cancer

Scientists discover how satellite RNA leads to cancer

by Salk InstituteCell with injected hSATa RNA (left) shows a high level of a marker for DNA damage, γH2AX (middle). Merge image (right) shows satellite RNA and γH2AX in cells; DNA is blue. Credit

Scientists discover how satellite RNA leads to cancer

by Salk InstituteCell with injected hSATa RNA (left) shows a high level of a marker for DNA damage, γH2AX (middle). Merge image (right) shows satellite RNA and γH2AX in cells; DNA is blue. Credit
Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA

Epigenetic mechanism associated with clinical outcome and therapeutic vulnerability in liver cancer

by Josep Carreras Leukaemia Research InstituteNSUN7 epigenetic loss occurs in human primary HCC tumors in association with worse clinical outcome. (A) Percentage of NSUN7 methylation in the TCGA
Scientists map the evolution of urinary tract cancer cells

Scientists map the evolution of urinary tract cancer cells

by Weill Cornell Medical CollegeImaging Mass Cytometry shows the immune-inflamed subtype of upper tract urothelial carcinoma at single-cell resolution. Red: tumor-expressed E-cadherin; Green: T-c

Scientists map the evolution of urinary tract cancer cells

by Weill Cornell Medical CollegeImaging Mass Cytometry shows the immune-inflamed subtype of upper tract urothelial carcinoma at single-cell resolution. Red: tumor-expressed E-cadherin; Green: T-c
Chemotherapy-resistant ovarian cancer cells protect their neighbors, shows study

Chemotherapy-resistant ovarian cancer cells protect their neighbors, shows study

by University of PittsburghCredit: Unsplash/CC0 Public DomainCertain chemotherapy-resistant ovarian cancer cells protect neighboring cancer cells by sending signals that induce resistance, accord

Chemotherapy-resistant ovarian cancer cells protect their neighbors, shows study

by University of PittsburghCredit: Unsplash/CC0 Public DomainCertain chemotherapy-resistant ovarian cancer cells protect neighboring cancer cells by sending signals that induce resistance, accord
Research points to potential new treatment for aggressive prostate cancer subtype

Research points to potential new treatment for aggressive prostate cancer subtype

byUniversity of MichiganProstate cancer cells. Credit: NIH Image GalleryWhen researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate c

Research points to potential new treatment for aggressive prostate cancer subtype

byUniversity of MichiganProstate cancer cells. Credit: NIH Image GalleryWhen researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate c