MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on: January 22,2024

MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on:January 22,2024

Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem

Updated on: March 05,2024

Researchers report on ctDNA-based detection of residual disease prognostic for resected CRC

by Elana GotkineFor patients with radically resected, stage II to IV colorectal cancer (CRC), circulating tumor (ct)DNA-based detection of molecular residual disease (MRD) in response to adjuvant chem

Updated on:March 05,2024

Specific components of the tumor immune microenvironment may affect responses to BCMA CAR T-cell therapy

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainPatients with myeloma whose tumor immune microenvironments had a more diverse baseline T-cell repertoire, fewer marker

Updated on: January 22,2024

Specific components of the tumor immune microenvironment may affect responses to BCMA CAR T-cell therapy

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainPatients with myeloma whose tumor immune microenvironments had a more diverse baseline T-cell repertoire, fewer marker

Updated on:January 22,2024

Prostate cancer: Can AI help to avoid unnecessary biopsies?

byGerman Cancer Research CenterRisk stratification example from the test cohort: a 66-year-old male presents with negative DRE, PSA elevation to 6.2 ng/mL, prostate volume of 82.5 mL, and PSAD o

Updated on: August 27,2024

Prostate cancer: Can AI help to avoid unnecessary biopsies?

byGerman Cancer Research CenterRisk stratification example from the test cohort: a 66-year-old male presents with negative DRE, PSA elevation to 6.2 ng/mL, prostate volume of 82.5 mL, and PSAD o

Updated on:August 27,2024

Research examines how to stay on task

by University of Texas at ArlingtonTask paradigm visual for a single trial on the four-choice reaction time task. Credit:Attention, Perception, & Psychophysics(2023). DOI: 10.3758

Updated on: March 12,2024

Research examines how to stay on task

by University of Texas at ArlingtonTask paradigm visual for a single trial on the four-choice reaction time task. Credit:Attention, Perception, & Psychophysics(2023). DOI: 10.3758

Updated on:March 12,2024

Genetically modified virus shown able to kill tumors in mice with retinoblastoma

by Bob Yirka , Medical XpressThe virus-based anticancer therapy (VCN-01) showed toxic effects against retinoblastoma cells after 12 days. Credit: G. Pascual-Pasto et al.,Science Translational Me

Updated on: April 01,2024

Genetically modified virus shown able to kill tumors in mice with retinoblastoma

by Bob Yirka , Medical XpressThe virus-based anticancer therapy (VCN-01) showed toxic effects against retinoblastoma cells after 12 days. Credit: G. Pascual-Pasto et al.,Science Translational Me

Updated on:April 01,2024

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on: March 12,2024

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on:March 12,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on: March 12,2024

Researchers identify novel oncogenic function for receptor linked to Alzheimer's disease

by University of TurkuCredit: CC0 Public DomainCommon and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been m

Updated on:March 12,2024

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on: March 30,2024

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on:March 30,2024

Engineered receptors help the immune system home in on cancer

byUniversity of California, San FranciscoCredit: CC0 Public DomainMost cancer treatments—from chemotherapies to engineered immune cells—have a host of side effects, in large part because they af

Updated on: November 30,2024

Engineered receptors help the immune system home in on cancer

byUniversity of California, San FranciscoCredit: CC0 Public DomainMost cancer treatments—from chemotherapies to engineered immune cells—have a host of side effects, in large part because they af

Updated on:November 30,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on: February 03,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on:February 03,2024

Drug resistance is a powerful menace in certain breast and ovarian cancers. Now scientists are figuring out why

by Delthia Ricks , Medical XpressCredit: Unsplash/CC0 Public DomainJust as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to ch

Updated on: February 18,2024

Drug resistance is a powerful menace in certain breast and ovarian cancers. Now scientists are figuring out why

by Delthia Ricks , Medical XpressCredit: Unsplash/CC0 Public DomainJust as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to ch

Updated on:February 18,2024