Study confirms curable state between single and widespread cancers

by University of Chicago Medical CenterRalph Weichselbaum, M.D., the Daniel K. Ludwig Distinguished Service Professor, chair of radiation and cellular oncology at UChicago and director of the Lud

Updated on: March 01,2024 17

Study confirms curable state between single and widespread cancers

by University of Chicago Medical CenterRalph Weichselbaum, M.D., the Daniel K. Ludwig Distinguished Service Professor, chair of radiation and cellular oncology at UChicago and director of the Lud

Updated on:March 01,2024 17

Team targets tumor suppressor to treat 'triple-negative' breast cancer

by University of Arizona Health SciencesAgnieszka Witkiewicz, MD and Erik Knudsen, PhD, UA Cancer Center. Credit: BioCommunications, Kris HanningA study by scientists at the University of Arizona Canc

Updated on: May 27,2024 4

Team targets tumor suppressor to treat 'triple-negative' breast cancer

by University of Arizona Health SciencesAgnieszka Witkiewicz, MD and Erik Knudsen, PhD, UA Cancer Center. Credit: BioCommunications, Kris HanningA study by scientists at the University of Arizona Canc

Updated on:May 27,2024 4

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on: January 30,2024 12

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on:January 30,2024 12

Potential new drug could target rare childhood brain tumor

Potential new drug could target rare childhood brain tumorA type of glioma. Credit: David Ellison, St. Jude Children’s Research HospitalRibociclib—a drug already used to treat breast cancer—may help s

Updated on: September 10,2024 0

Potential new drug could target rare childhood brain tumor

Potential new drug could target rare childhood brain tumorA type of glioma. Credit: David Ellison, St. Jude Children’s Research HospitalRibociclib—a drug already used to treat breast cancer—may help s

Updated on:September 10,2024 0

AZD6738 found to slow some types of children's tumor growth in mouse models

by Bob Yirka , Medical XpressCredit: CC0 Public Domain(Medical Xpress)—A team of researchers from the U.S., Germany and Japan has found that the chemical AZD6738 was able to slow some childhood type t

Updated on: April 22,2024 14

AZD6738 found to slow some types of children's tumor growth in mouse models

by Bob Yirka , Medical XpressCredit: CC0 Public Domain(Medical Xpress)—A team of researchers from the U.S., Germany and Japan has found that the chemical AZD6738 was able to slow some childhood type t

Updated on:April 22,2024 14

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on: March 30,2024 0

Study successfully mimics complex neuroblastoma vasculature on a chip to explore treatments

by Institute for Bioengineering of CataloniaGraphical abstract. Credit:Cancers(2024). DOI: 10.3390/cancers16051060Neuroblastoma, one of the most common childhood cancers, is classified as

Updated on:March 30,2024 0

Study highlights how lower-income, working cancer caregivers experience harder financial impacts

by Rachel Sauer,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainCancer is a disease of ripples—from symptoms that precede a diagnosis to treatment, side effects, and goals for long-te

Updated on: February 18,2024 20

Study highlights how lower-income, working cancer caregivers experience harder financial impacts

by Rachel Sauer,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainCancer is a disease of ripples—from symptoms that precede a diagnosis to treatment, side effects, and goals for long-te

Updated on:February 18,2024 20

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on: April 01,2024 0

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on:April 01,2024 0

Tracing cancer back to birth uncovers promising biomarkers for prevention, targeted treatment of childhood leukemia

byMurdoch Children's Research InstituteDiscovery, validation and functional analysis of VTRNA2-1 methylation in association with pediatric pre-B ALL development. Credit:Molecular Cance

Updated on: November 11,2024 0

Tracing cancer back to birth uncovers promising biomarkers for prevention, targeted treatment of childhood leukemia

byMurdoch Children's Research InstituteDiscovery, validation and functional analysis of VTRNA2-1 methylation in association with pediatric pre-B ALL development. Credit:Molecular Cance

Updated on:November 11,2024 0

Researchers unveil experimental compound to block therapeutic target in blood cancer

by UNC Lineberger Comprehensive Cancer CenterBlossom Damania, PhD, Jason Wang and a team of UNC Lineberger researchers report in PNAS they have discovered a hyperactive cell signal that contribut

Updated on: June 15,2024 7

Researchers unveil experimental compound to block therapeutic target in blood cancer

by UNC Lineberger Comprehensive Cancer CenterBlossom Damania, PhD, Jason Wang and a team of UNC Lineberger researchers report in PNAS they have discovered a hyperactive cell signal that contribut

Updated on:June 15,2024 7

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep

Updated on: January 22,2024 15

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep

Updated on:January 22,2024 15

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on: April 28,2024 0

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on:April 28,2024 0