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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Study details how exosomes, released by the breast tumor, tricks cells in the blood-brain barrier into taking them up

Study details how exosomes, released by the breast tumor, tricks cells in the blood-brain barrier into taking them up

by Children's Hospital BostonExtracellular vesicles, also known as exosomes, cross the blood-brain barrier via a transcytosis process. Credit: Kristin Johnson/Vascular Biology Program, Boston

Study details how exosomes, released by the breast tumor, tricks cells in the blood-brain barrier into taking them up

by Children's Hospital BostonExtracellular vesicles, also known as exosomes, cross the blood-brain barrier via a transcytosis process. Credit: Kristin Johnson/Vascular Biology Program, Boston
AI tool predicts cancer gene activity from biopsy images

AI tool predicts cancer gene activity from biopsy images

by Sarah C.P. Williams,Stanford University Medical CenterA new AI program, SEQUOIA, can analyze a microscopy image from a tumor biopsy (left, purple) and rapidly determine what genes are likely

AI tool predicts cancer gene activity from biopsy images

by Sarah C.P. Williams,Stanford University Medical CenterA new AI program, SEQUOIA, can analyze a microscopy image from a tumor biopsy (left, purple) and rapidly determine what genes are likely
Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

by Adam Pope,University of Alabama at BirminghamProtein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. Th

Study identifies a potential therapeutic target for triple-negative breast cancer in Black patients

by Adam Pope,University of Alabama at BirminghamProtein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. Th
New study estimates preventable cancer burden linked to poor diet in the US

New study estimates preventable cancer burden linked to poor diet in the US

by Tufts UniversityA new study estimates that 5.2 percent of new invasive cancer cases reported in 2015 are associated with poor diets. Credit: Nako Kobayashi/Tufts UniversityA new modeling study

New study estimates preventable cancer burden linked to poor diet in the US

by Tufts UniversityA new study estimates that 5.2 percent of new invasive cancer cases reported in 2015 are associated with poor diets. Credit: Nako Kobayashi/Tufts UniversityA new modeling study
On a stretch of gravel road, families ravaged by cancer question nitrate

On a stretch of gravel road, families ravaged by cancer question nitrate

by Jennifer Bjorhus, Star TribuneCredit: Unsplash/CC0 Public DomainCancer ravaged Brian Bennerotte's body and those of many around him—his father, five brothers and his sister—as well as others al

On a stretch of gravel road, families ravaged by cancer question nitrate

by Jennifer Bjorhus, Star TribuneCredit: Unsplash/CC0 Public DomainCancer ravaged Brian Bennerotte's body and those of many around him—his father, five brothers and his sister—as well as others al
Investigators map genomic landscape of very rare cancer

Investigators map genomic landscape of very rare cancer

by Tom Wilemon,Vanderbilt UniversityKiller T cells surround a cancer cell. Credit: NIHA team of Vanderbilt researchers mapped out the genomic landscape of a metastatic malignant proliferating tr

Investigators map genomic landscape of very rare cancer

by Tom Wilemon,Vanderbilt UniversityKiller T cells surround a cancer cell. Credit: NIHA team of Vanderbilt researchers mapped out the genomic landscape of a metastatic malignant proliferating tr
Researchers discover the Achilles' heel of an aggressive brain cancer

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen

Researchers discover the Achilles' heel of an aggressive brain cancer

by University of HelsinkiGlioblastoma cells (red) are known to invade the brain (blue). Figure shows patient-derived glioblastoma in murine brain treated with saline (control). Credit: Laakkonen
Active surveillance OK for non-muscle invasive bladder cancer

Active surveillance OK for non-muscle invasive bladder cancer

(HealthDay)—For patients with non-muscle invasive bladder cancer, active surveillance seems reasonable and cost-effective, according to a study published in the February issue ofThe Journal of U

Active surveillance OK for non-muscle invasive bladder cancer

(HealthDay)—For patients with non-muscle invasive bladder cancer, active surveillance seems reasonable and cost-effective, according to a study published in the February issue ofThe Journal of U
Researchers characterize mechanism of action of CAR T cells

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci
Therapeutic and diagnostic functions of one antibody for pancreatic cancer

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting

Therapeutic and diagnostic functions of one antibody for pancreatic cancer

by Osaka UniversityFig.1: DKK1–CKAP4 signaling and application of the anti-CKAP4 antibody. DKK1 and CKAP4 are overexpressed in cancer cells and the PI3 kinase–AKT pathway is activated, promoting
The sugar-attaching enzyme that defines colon cancer

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat
A chemistry pioneer works to improve a flawed test for a common cancer

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a