Researchers peer inside cells to spy on cancer's on-off switch

by Lisa Marshall,University of Colorado at BoulderCredit: University of Colorado at BoulderForty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins ca

Updated on: June 06,2024 6

Researchers peer inside cells to spy on cancer's on-off switch

by Lisa Marshall,University of Colorado at BoulderCredit: University of Colorado at BoulderForty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins ca

Updated on:June 06,2024 6

Scientists consider fighting potentially lethal form of breast cancer with chemical produced by the disease

by Delthia Ricks , Medical XpressSchematic model of GDP-M regulating HRD and immunity through promoting BRCA2 degradation. Credit:Science Translational Medicine(2024). DOI: 10.1126/scitran

Updated on: March 30,2024 0

Scientists consider fighting potentially lethal form of breast cancer with chemical produced by the disease

by Delthia Ricks , Medical XpressSchematic model of GDP-M regulating HRD and immunity through promoting BRCA2 degradation. Credit:Science Translational Medicine(2024). DOI: 10.1126/scitran

Updated on:March 30,2024 0

Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase

by SLAS (Society for Laboratory Automation and Screening)ALDOA catalyzes the reversible aldol cleavage of fructose-1,6-bisphosphate (F-1,6-BP) into D-Glyceraldehyde-3-phosphate (GAP) and dihydroxyacet

Updated on: March 01,2024 17

Assay to ID anticancer reagents targeting fructose-1,6-bisphosphate aldolase

by SLAS (Society for Laboratory Automation and Screening)ALDOA catalyzes the reversible aldol cleavage of fructose-1,6-bisphosphate (F-1,6-BP) into D-Glyceraldehyde-3-phosphate (GAP) and dihydroxyacet

Updated on:March 01,2024 17

Study highlights how lower-income, working cancer caregivers experience harder financial impacts

by Rachel Sauer,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainCancer is a disease of ripples—from symptoms that precede a diagnosis to treatment, side effects, and goals for long-te

Updated on: February 18,2024 20

Study highlights how lower-income, working cancer caregivers experience harder financial impacts

by Rachel Sauer,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainCancer is a disease of ripples—from symptoms that precede a diagnosis to treatment, side effects, and goals for long-te

Updated on:February 18,2024 20

Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on: May 25,2024 8

Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on:May 25,2024 8

Researchers image live drug response and resistant 'pockets' in pancreatic cancer

by Garvan Institute of Medical ResearchSchematic of spatiotemporal AKT activity mapping in several organ systems in vivo.Optical window–mediated intravital assessment of metabolic and malignancy-

Updated on: February 18,2024 10

Researchers image live drug response and resistant 'pockets' in pancreatic cancer

by Garvan Institute of Medical ResearchSchematic of spatiotemporal AKT activity mapping in several organ systems in vivo.Optical window–mediated intravital assessment of metabolic and malignancy-

Updated on:February 18,2024 10

New treatment trialed in mice offers hope for advanced liver cancer

by Centenary InstituteCD5-2 treatment improved tumor vessels structure. Representative scanning electron microscopy images of liver tumor blood vessels in the different treatment groups. Qualitat

Updated on: February 18,2024 19

New treatment trialed in mice offers hope for advanced liver cancer

by Centenary InstituteCD5-2 treatment improved tumor vessels structure. Representative scanning electron microscopy images of liver tumor blood vessels in the different treatment groups. Qualitat

Updated on:February 18,2024 19

Potential probe for early ovarian cancer

by Anivarya Kumar,Vanderbilt UniversityFigure 1. (a) Structure of COX-2-selective inhibitors (celecoxib, rofecoxib, and valdecoxib) and COX-1-selective inhibitors (SC560, P6/18F-P6, and VU048783

Updated on: April 20,2024 14

Potential probe for early ovarian cancer

by Anivarya Kumar,Vanderbilt UniversityFigure 1. (a) Structure of COX-2-selective inhibitors (celecoxib, rofecoxib, and valdecoxib) and COX-1-selective inhibitors (SC560, P6/18F-P6, and VU048783

Updated on:April 20,2024 14

Study: Race, ethnicity may play a role in cause of liver cancer

by University of Miami Leonard M. Miller School of MedicineCredit: Pixabay/CC0 Public DomainA new analysis of liver cancer has identified racial and ethnic differences and emerging trends for thi

Updated on: January 29,2024 14

Study: Race, ethnicity may play a role in cause of liver cancer

by University of Miami Leonard M. Miller School of MedicineCredit: Pixabay/CC0 Public DomainA new analysis of liver cancer has identified racial and ethnic differences and emerging trends for thi

Updated on:January 29,2024 14

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on: April 28,2024 0

Periostin shows promise to help fight a common form of esophageal cancer

byElsevierSchematic diagram of roles of periostin (POSTN) in the esophageal squamous cell carcinoma (ESCC) microenvironment. Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to

Updated on:April 28,2024 0

Researchers identify effective drug combination against uveal melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Uveal mela

Updated on: June 08,2024 5

Researchers identify effective drug combination against uveal melanoma

by H. Lee Moffitt Cancer Center & Research InstituteMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Uveal mela

Updated on:June 08,2024 5

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Updated on: August 03,2024 0

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

byPerelman School of Medicine at the University of PennsylvaniaCD5 KO enhances CAR T cell cytotoxicity. Credit:Science Immunology(2024). DOI: 10.1126/sciimmunol.adn6509The effectiven

Updated on:August 03,2024 0