Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on: May 09,2024

Elegant antibody nanoparticles override immunological tolerance of tumors

by Chinese Academy of SciencesSchematic illustration of the engineered antibody nanoparticle for robust cancer immunotherapy. Credit: WANG DanggeImmune checkpoint blockade (ICB) therapy using the

Updated on:May 09,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on: February 20,2024

Researchers identify key metabolic regulators of drug resistance in the fight against pancreatic cancer

by Rebecca Brierley,University at BuffaloGraphical abstract. Credit:Molecular & Cellular Proteomics(2022). DOI: 10.1016/j.mcpro.2022.100409Researchers from the University at Buff

Updated on:February 20,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on: July 02,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on:July 02,2024

Mechanism of a breast cancer drug points to a possible new therapy

by Sarah Avery,Duke UniversityThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on: May 20,2024

Mechanism of a breast cancer drug points to a possible new therapy

by Sarah Avery,Duke UniversityThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on:May 20,2024

Novel allogeneic CAR T cell therapy shows promising results in patients with metastatic clear cell renal cell carcinoma

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe CD70-targeting allogeneic chimeric antigen receptor (CAR) T cell therapy, ALLO-316, demonstrated encouragin

Updated on: January 15,2024

Novel allogeneic CAR T cell therapy shows promising results in patients with metastatic clear cell renal cell carcinoma

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe CD70-targeting allogeneic chimeric antigen receptor (CAR) T cell therapy, ALLO-316, demonstrated encouragin

Updated on:January 15,2024

Novel pretargeted radionuclide therapy for HER2-expressing cancers shows promise

by Society of Nuclear Medicine and Molecular ImagingTransversal (A), coronal (B), sagittal (C) nanoSPECT/CT images and maximum intensity projection (D) obtained 30 h after injection of pretargeted&nbs

Updated on: March 06,2024

Novel pretargeted radionuclide therapy for HER2-expressing cancers shows promise

by Society of Nuclear Medicine and Molecular ImagingTransversal (A), coronal (B), sagittal (C) nanoSPECT/CT images and maximum intensity projection (D) obtained 30 h after injection of pretargeted&nbs

Updated on:March 06,2024

Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin

Updated on: January 02,2024

Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin

Updated on:January 02,2024

Deep learning and radiomics allow precise differentiation in brain tumors

by Karl Landsteiner University of Health SciencesGeneral diagram of the proposed radiomics and radiophysiomics approach, showing the major steps: MRI data acquisition, calculation of MRI biomarker map

Updated on: January 04,2024

Deep learning and radiomics allow precise differentiation in brain tumors

by Karl Landsteiner University of Health SciencesGeneral diagram of the proposed radiomics and radiophysiomics approach, showing the major steps: MRI data acquisition, calculation of MRI biomarker map

Updated on:January 04,2024

Doctors are being sexually harassed at work—this needs to stop

by Louise Stone,The ConversationCredit: Unsplash/CC0 Public DomainDominique Leewas training in radiation oncology when she was invited to join her supervisor to discuss a training opportun

Updated on: May 25,2024

Doctors are being sexually harassed at work—this needs to stop

by Louise Stone,The ConversationCredit: Unsplash/CC0 Public DomainDominique Leewas training in radiation oncology when she was invited to join her supervisor to discuss a training opportun

Updated on:May 25,2024

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on: February 03,2024

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on:February 03,2024

Exercise can reduce severity of breast cancer treatment side effects

by Edith Cowan UniversityCredit: Pixabay/CC0 Public DomainBreast cancer is the most common form of the disease among women; in Australia, one in eight women will be diagnosed with breast cancer b

Updated on: February 03,2024

Exercise can reduce severity of breast cancer treatment side effects

by Edith Cowan UniversityCredit: Pixabay/CC0 Public DomainBreast cancer is the most common form of the disease among women; in Australia, one in eight women will be diagnosed with breast cancer b

Updated on:February 03,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on: June 15,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on:June 15,2024