A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on: January 29,2024

A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on:January 29,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on: January 22,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on:January 22,2024

Study reveals factors that influence participation in bowel cancer screening

by Isabelle Dubach,University of New South WalesCredit: Unsplash/CC0 Public DomainA new, Australian-first study by Cancer Council NSW has shed light on the factors that influence whether or not

Updated on: July 02,2024

Study reveals factors that influence participation in bowel cancer screening

by Isabelle Dubach,University of New South WalesCredit: Unsplash/CC0 Public DomainA new, Australian-first study by Cancer Council NSW has shed light on the factors that influence whether or not

Updated on:July 02,2024

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Updated on: January 03,2024

Resistance of mammary fibrosis to immune checkpoint therapy linked to macrophage infiltration, Wnt pathway expression

by Impact Journals LLCWnt pathway expression in tumors from NeuT/ATTAC mice. Credit: 2022 Yuan et al.A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint

Updated on:January 03,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on: April 07,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on:April 07,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Stress-tolerant cells shown to drive tumor initiation in pancreatic cancer

by University of California - San DiegoTumor-initiating cells (blue) produce an extracellular matrix containing fibronectin (pink) which gives them increased stress tolerance, drug resistance and

Updated on: February 23,2024

Stress-tolerant cells shown to drive tumor initiation in pancreatic cancer

by University of California - San DiegoTumor-initiating cells (blue) produce an extracellular matrix containing fibronectin (pink) which gives them increased stress tolerance, drug resistance and

Updated on:February 23,2024

Study discovers triple immunotherapy combination as possible treatment for pancreatic cancer

by University of Texas M. D. Anderson Cancer CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainResearchers at The University of Texa

Updated on: January 30,2024

Study discovers triple immunotherapy combination as possible treatment for pancreatic cancer

by University of Texas M. D. Anderson Cancer CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainResearchers at The University of Texa

Updated on:January 30,2024

New treatment approach for prostate cancer could stop resistance in its tracks

bySanford Burnham Prebys Medical Discovery InstituteProstate cancer cells. Credit: NIH Image GalleryFor the first time, researchers have discovered that prostate cancer can be killed by targetin

Updated on: January 02,2024

New treatment approach for prostate cancer could stop resistance in its tracks

bySanford Burnham Prebys Medical Discovery InstituteProstate cancer cells. Credit: NIH Image GalleryFor the first time, researchers have discovered that prostate cancer can be killed by targetin

Updated on:January 02,2024

A brief cognitive behavioral therapy appears promising for head and neck cancer survivors

by Medical University of South CarolinaA microvascular reconstructive surgeon by training, Dr. Evan Graboyes became interested in alleviating body-image distress when he saw how much his head and

Updated on: February 03,2024

A brief cognitive behavioral therapy appears promising for head and neck cancer survivors

by Medical University of South CarolinaA microvascular reconstructive surgeon by training, Dr. Evan Graboyes became interested in alleviating body-image distress when he saw how much his head and

Updated on:February 03,2024

Study finds Black patients wait longer for uterine cancer testing, diagnosis

by Mallory Locklear,Yale UniversityCredit: Unsplash/CC0 Public DomainEarly diagnosis of uterine cancer is known to improve a patient's chances for survival, but previous research has found t

Updated on: February 18,2024

Study finds Black patients wait longer for uterine cancer testing, diagnosis

by Mallory Locklear,Yale UniversityCredit: Unsplash/CC0 Public DomainEarly diagnosis of uterine cancer is known to improve a patient's chances for survival, but previous research has found t

Updated on:February 18,2024

High ambient temperature in pregnancy associated with childhood leukemia

byYale UniversityCredit: Pixabay/CC0 Public DomainAs climate change warms the planet, high ambient temperatures are expected to be more common and intense over the coming decades in the U.S. and

Updated on: July 05,2024

High ambient temperature in pregnancy associated with childhood leukemia

byYale UniversityCredit: Pixabay/CC0 Public DomainAs climate change warms the planet, high ambient temperatures are expected to be more common and intense over the coming decades in the U.S. and

Updated on:July 05,2024