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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Addition of maintenance olaparib slows advanced ovarian cancer

Addition of maintenance olaparib slows advanced ovarian cancer

(HealthDay)—Compared with placebo, the addition of olaparib to maintenance therapy with bevacizumab is associated with a significant progression-free survival benefit for patients with advanced ovaria

Addition of maintenance olaparib slows advanced ovarian cancer

(HealthDay)—Compared with placebo, the addition of olaparib to maintenance therapy with bevacizumab is associated with a significant progression-free survival benefit for patients with advanced ovaria
Rainbow of fruit and veg the best prevention against prostate cancer

Rainbow of fruit and veg the best prevention against prostate cancer

byUniversity of South AustraliaCredit: Unsplash/CC0 Public DomainMen who consume colorful fruits and vegetables on a regular basis are less likely to be diagnosed with prostate cancer (PC), acco

Rainbow of fruit and veg the best prevention against prostate cancer

byUniversity of South AustraliaCredit: Unsplash/CC0 Public DomainMen who consume colorful fruits and vegetables on a regular basis are less likely to be diagnosed with prostate cancer (PC), acco
Ultrasound-guided surgery could be quicker, less painful and more effective for treating early form of breast cancer

Ultrasound-guided surgery could be quicker, less painful and more effective for treating early form of breast cancer

by European Organisation for Research and Treatment of CancerAntonio Esgueva using IOUS to guide breast surgery. Credit: Antonio Esguega / EORTCUsing ultrasound to guide surgery for patients with duct

Ultrasound-guided surgery could be quicker, less painful and more effective for treating early form of breast cancer

by European Organisation for Research and Treatment of CancerAntonio Esgueva using IOUS to guide breast surgery. Credit: Antonio Esguega / EORTCUsing ultrasound to guide surgery for patients with duct
Report: Cancer deaths continue downward trend, modest improvements in survival for pancreatic cancer

Report: Cancer deaths continue downward trend, modest improvements in survival for pancreatic cancer

byNational Cancer InstituteAge-standardized, delay-adjusted overall cancer incidence rates (2014–2018) and age-standardized overall cancer death rates (2015–2019) are illustrated for all cancer

Report: Cancer deaths continue downward trend, modest improvements in survival for pancreatic cancer

byNational Cancer InstituteAge-standardized, delay-adjusted overall cancer incidence rates (2014–2018) and age-standardized overall cancer death rates (2015–2019) are illustrated for all cancer
Radiotherapy for hard-to-treat bladder cancer

Radiotherapy for hard-to-treat bladder cancer

byInstitute of Cancer ResearchCredit: Institute of Cancer ResearchMore targeted forms of radiotherapy can effectively treat bladder cancer which has spread to the lymph nodes of the pelvis, acco

Radiotherapy for hard-to-treat bladder cancer

byInstitute of Cancer ResearchCredit: Institute of Cancer ResearchMore targeted forms of radiotherapy can effectively treat bladder cancer which has spread to the lymph nodes of the pelvis, acco
CHMP Recommends Against Renewal of Marketing Authorization for Belantamab Mafodotin in R/R Myeloma

CHMP Recommends Against Renewal of Marketing Authorization for Belantamab Mafodotin in R/R Myeloma

September 18, 2023Chris RyanThe European Medicines Agency’s Committee for Medicinal Products for Human Use has recommended against renewal of the conditional marketing authorization for belantamab maf

CHMP Recommends Against Renewal of Marketing Authorization for Belantamab Mafodotin in R/R Myeloma

September 18, 2023Chris RyanThe European Medicines Agency’s Committee for Medicinal Products for Human Use has recommended against renewal of the conditional marketing authorization for belantamab maf
Study finds carcinogen exposure makes cancer cells more susceptible to immune attack

Study finds carcinogen exposure makes cancer cells more susceptible to immune attack

by Liz Murphy,Massachusetts General HospitalCarcinogen-exposed cancer cells transform that nature of tumor-infiltrating macrophages from immunosuppressive (left) to immune activating agents (rig

Study finds carcinogen exposure makes cancer cells more susceptible to immune attack

by Liz Murphy,Massachusetts General HospitalCarcinogen-exposed cancer cells transform that nature of tumor-infiltrating macrophages from immunosuppressive (left) to immune activating agents (rig
Atezolizumab Plus Bevacizumab and Chemotherapy Fails to Provide PFS Benefit in Platinum-Sensitive

Atezolizumab Plus Bevacizumab and Chemotherapy Fails to Provide PFS Benefit in Platinum-Sensitive

September 13, 2023Kyle DohertyThe addition of the PD-L1 inhibitor atezolizumab to bevacizumab and platinum-based chemotherapy did not result in a statistically significant progression-free survival be

Atezolizumab Plus Bevacizumab and Chemotherapy Fails to Provide PFS Benefit in Platinum-Sensitive

September 13, 2023Kyle DohertyThe addition of the PD-L1 inhibitor atezolizumab to bevacizumab and platinum-based chemotherapy did not result in a statistically significant progression-free survival be
Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

July 14, 2023Caroline SeymourHigher levels of baseline TCR clonality in peripheral blood mononuclear cells (PBMCs) and baseline IgG1 fraction in PBMCs and tumor tissue were identified in an institutio

Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

July 14, 2023Caroline SeymourHigher levels of baseline TCR clonality in peripheral blood mononuclear cells (PBMCs) and baseline IgG1 fraction in PBMCs and tumor tissue were identified in an institutio
Drug development in stem cell-derived liver organoid models

Drug development in stem cell-derived liver organoid models

To ensure that new drugs are effective and have as little toxicity as possible, they first need to be tested in model systems before entering clinical trials. In this Q&A, Dr Takanori Takebe outli

Drug development in stem cell-derived liver organoid models

To ensure that new drugs are effective and have as little toxicity as possible, they first need to be tested in model systems before entering clinical trials. In this Q&A, Dr Takanori Takebe outli
Scientists unveil chemotherapy resistance mechanism related to p53 mutation

Scientists unveil chemotherapy resistance mechanism related to p53 mutation

by Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem (INBEB)Comparison between the response of tumoral cells to chemotherapy with no mutation of p53 (upper cells) and of mu

Scientists unveil chemotherapy resistance mechanism related to p53 mutation

by Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem (INBEB)Comparison between the response of tumoral cells to chemotherapy with no mutation of p53 (upper cells) and of mu
Study finds less-aggressive chemotherapy after initial treatment for metastatic colorectal cancer to be more beneficial

Study finds less-aggressive chemotherapy after initial treatment for metastatic colorectal cancer to be more beneficial

byMayo ClinicCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0A Mayo Clinic study involving 5,540 patients with metastatic colorectal cancer finds that maintenanc

Study finds less-aggressive chemotherapy after initial treatment for metastatic colorectal cancer to be more beneficial

byMayo ClinicCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0A Mayo Clinic study involving 5,540 patients with metastatic colorectal cancer finds that maintenanc