Heterogeneity of liver cancer cells helps explain tumor progression in patients

byThe Mount Sinai HospitalCredit: CC0 Public DomainMany liver cancer tumors contain a highly diverse set of cells, a phenomenon known as intra-tumor heterogeneity that can significantly affect t

Updated on: December 20,2023 25

Heterogeneity of liver cancer cells helps explain tumor progression in patients

byThe Mount Sinai HospitalCredit: CC0 Public DomainMany liver cancer tumors contain a highly diverse set of cells, a phenomenon known as intra-tumor heterogeneity that can significantly affect t

Updated on:December 20,2023 25

'No one should cancel their colonoscopies': Addressing controversy from a recent clinical trial

by Leslie Orr,University of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainDespite some confusing messages this week around the value of colonoscopies, Wilmot Cancer Institute physici

Updated on: December 28,2023 9

'No one should cancel their colonoscopies': Addressing controversy from a recent clinical trial

by Leslie Orr,University of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainDespite some confusing messages this week around the value of colonoscopies, Wilmot Cancer Institute physici

Updated on:December 28,2023 9

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on: December 25,2023 10

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on:December 25,2023 10

Localized genetic mutations may serve as biomarker for wide range of cancers

by Melissa Rohman,Northwestern UniversityCredit: Brianna Monroe/Northwestern UniversityA team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind

Updated on: December 26,2023 5

Localized genetic mutations may serve as biomarker for wide range of cancers

by Melissa Rohman,Northwestern UniversityCredit: Brianna Monroe/Northwestern UniversityA team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind

Updated on:December 26,2023 5

Scientists discover a new way to prevent secondary breast cancer

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainScientists have discovered why breast cancer cells that have spread to the lungs may "wake up" following years of sleep,

Updated on: December 27,2023 12

Scientists discover a new way to prevent secondary breast cancer

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainScientists have discovered why breast cancer cells that have spread to the lungs may "wake up" following years of sleep,

Updated on:December 27,2023 12

National quality improvement initiative successfully helps address pandemic-related cancer screening deficits

byAmerican College of SurgeonsMean Monthly Screening Test Volumes in April Through November. 2021 April and May 2021 is the preintervention period. Vertical dotted line indicates the start of th

Updated on: December 23,2023 10

National quality improvement initiative successfully helps address pandemic-related cancer screening deficits

byAmerican College of SurgeonsMean Monthly Screening Test Volumes in April Through November. 2021 April and May 2021 is the preintervention period. Vertical dotted line indicates the start of th

Updated on:December 23,2023 10

Collaborative initiative to unravel the role of HLA in individuals with a genetic cancer predisposition

by Peter Saueressig,Heidelberg UniversityGraphical abstract. Credit:International Journal of Cancer(2022). DOI: 10.1002/ijc.34312Scientists from the Heidelberg Institute for Theoreti

Updated on: December 24,2023 10

Collaborative initiative to unravel the role of HLA in individuals with a genetic cancer predisposition

by Peter Saueressig,Heidelberg UniversityGraphical abstract. Credit:International Journal of Cancer(2022). DOI: 10.1002/ijc.34312Scientists from the Heidelberg Institute for Theoreti

Updated on:December 24,2023 10

Clinical trial shows significant disease-free survival for patients diagnosed with non-small cell lung cancer

byYale UniversityDFS per investigator assessment. Kaplan-Meier estimates of duration of (A) DFS in patients with stage II-IIIA disease and (B) in the overall population (stage IB-IIIA) by sevent

Updated on: December 28,2023 10

Clinical trial shows significant disease-free survival for patients diagnosed with non-small cell lung cancer

byYale UniversityDFS per investigator assessment. Kaplan-Meier estimates of duration of (A) DFS in patients with stage II-IIIA disease and (B) in the overall population (stage IB-IIIA) by sevent

Updated on:December 28,2023 10

Huge delays in dealing with complaints against UK drug companies revealed

by British Medical JournalCredit: Pixabay/CC0 Public DomainProcessing times for complaints against drug companies suspected of having breached their industry code of practice have more than tripl

Updated on: April 23,2024 12

Huge delays in dealing with complaints against UK drug companies revealed

by British Medical JournalCredit: Pixabay/CC0 Public DomainProcessing times for complaints against drug companies suspected of having breached their industry code of practice have more than tripl

Updated on:April 23,2024 12

Third-generation anti-CD19 CAR T-cells show efficacy without neurotoxicity in B-cell lymphoma phase 1 clinical trial

byMalaghan Institute of Medical ResearchMalaghan Institute GMP lab where CAR T-cells were manufactured for the phase 1 trial. Credit: Malaghan Institute of Medical ResearchThe Malaghan Institute

Updated on: January 26,2024 23

Third-generation anti-CD19 CAR T-cells show efficacy without neurotoxicity in B-cell lymphoma phase 1 clinical trial

byMalaghan Institute of Medical ResearchMalaghan Institute GMP lab where CAR T-cells were manufactured for the phase 1 trial. Credit: Malaghan Institute of Medical ResearchThe Malaghan Institute

Updated on:January 26,2024 23

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on: December 20,2023 10

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on:December 20,2023 10

Why lung cancer doesn't respond well to immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyA new MIT study explains why dendritic cells (green) in lymph nodes that drain from the lungs fail to stimulate killer T cells (white) to att

Updated on: January 08,2024 10

Why lung cancer doesn't respond well to immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyA new MIT study explains why dendritic cells (green) in lymph nodes that drain from the lungs fail to stimulate killer T cells (white) to att

Updated on:January 08,2024 10