Newly developed mathematical model could be used to predict cancer drug side effects in individuals

byKobe UniversityA bar graph to show drug metabolism predictions for the anti-cancer agent Irinotecan (the gray bars are the predictions and the black bars are the actual results). The shorter t

Updated on: December 22,2023 23

Newly developed mathematical model could be used to predict cancer drug side effects in individuals

byKobe UniversityA bar graph to show drug metabolism predictions for the anti-cancer agent Irinotecan (the gray bars are the predictions and the black bars are the actual results). The shorter t

Updated on:December 22,2023 23

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on: April 27,2024 0

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on:April 27,2024 0

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on: January 04,2024 13

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on:January 04,2024 13

Magrolimab/Azacitidine Combo Shows Efficacy for Untreated TP53-Mutant AML

December 2023Leah LawrencePatients with previously untreated acute myeloid leukemia (AML) who were not candidates for intensive chemotherapy experienced disease response when treated with a combinatio

Updated on: February 18,2024 8

Magrolimab/Azacitidine Combo Shows Efficacy for Untreated TP53-Mutant AML

December 2023Leah LawrencePatients with previously untreated acute myeloid leukemia (AML) who were not candidates for intensive chemotherapy experienced disease response when treated with a combinatio

Updated on:February 18,2024 8

Researchers shed light on cancer drug resistance, potential to expand use of PARP inhibitors across cancer types

byThe University of Hong KongInactivation of a DNA repair gene called FANCM enhances the formation of DNA damage and chromosomal instability induced by a PARP inhibitor, leading to massive cance

Updated on: August 27,2024 0

Researchers shed light on cancer drug resistance, potential to expand use of PARP inhibitors across cancer types

byThe University of Hong KongInactivation of a DNA repair gene called FANCM enhances the formation of DNA damage and chromosomal instability induced by a PARP inhibitor, leading to massive cance

Updated on:August 27,2024 0

CEACAMS 1, 5, and 6 in disease and cancer: Interactions with pathogens

by Impact Journals LLCSignaling of dimeric CEACAM1 long tail isoform in epithelial cells and T cells. Credit:Genes & Cancer(2023). DOI: 10.18632/genesandcancer.230A new review was rece

Updated on: December 25,2023 10

CEACAMS 1, 5, and 6 in disease and cancer: Interactions with pathogens

by Impact Journals LLCSignaling of dimeric CEACAM1 long tail isoform in epithelial cells and T cells. Credit:Genes & Cancer(2023). DOI: 10.18632/genesandcancer.230A new review was rece

Updated on:December 25,2023 10

New drug could unlock benefits of immunotherapy for more patients

FEBRUARY 27, 2024byInstitute of Cancer ResearchAntitumor responses. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI175369A new drug could offer a powerful way to sen

Updated on: March 25,2024 11

New drug could unlock benefits of immunotherapy for more patients

FEBRUARY 27, 2024byInstitute of Cancer ResearchAntitumor responses. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI175369A new drug could offer a powerful way to sen

Updated on:March 25,2024 11

The way genes are switched on in one-cell embryos may resemble the trigger for cancer

byUniversity of BathGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112023When an embryo is formed, its genes—donated by a fertilizing sperm and egg—are sil

Updated on: December 25,2023 9

The way genes are switched on in one-cell embryos may resemble the trigger for cancer

byUniversity of BathGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112023When an embryo is formed, its genes—donated by a fertilizing sperm and egg—are sil

Updated on:December 25,2023 9

Colon cancer is being spotted in younger people, and at later stages

by Steven ReinbergColon cancer continues to rise among younger U.S. adults, with the American Cancer Society reporting a doubling of cases in people younger than 55 in about 25 years.Also, significant

Updated on: December 26,2023 8

Colon cancer is being spotted in younger people, and at later stages

by Steven ReinbergColon cancer continues to rise among younger U.S. adults, with the American Cancer Society reporting a doubling of cases in people younger than 55 in about 25 years.Also, significant

Updated on:December 26,2023 8

Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival

byUniversity of Texas M. D. Anderson Cancer CenterW. Fraser Symmans, M.D. Credit: MD Anderson Cancer CenterResearchers from The University of Texas MD Anderson Cancer Center today reported resul

Updated on: December 22,2023 15

Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival

byUniversity of Texas M. D. Anderson Cancer CenterW. Fraser Symmans, M.D. Credit: MD Anderson Cancer CenterResearchers from The University of Texas MD Anderson Cancer Center today reported resul

Updated on:December 22,2023 15

Experts assess promise of vamorolone to treat Duchenne muscular dystrophy

by IOS PressSkeletal muscle fibers. Credit: Berkshire Community College Bioscience Image Library / Public domainThe drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duch

Updated on: May 26,2024 4

Experts assess promise of vamorolone to treat Duchenne muscular dystrophy

by IOS PressSkeletal muscle fibers. Credit: Berkshire Community College Bioscience Image Library / Public domainThe drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duch

Updated on:May 26,2024 4

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6

Updated on: May 26,2024 8

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6

Updated on:May 26,2024 8