Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on: January 04,2024 9

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on:January 04,2024 9

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on: December 22,2023 10

Disorderly DNA helps cancer cells evade treatment

byNorthwestern UniversityWhen the chromatin packing is heterogenous and disordered, a cell demonstrates more plasticity. Credit: Northwestern UniversityEach cell in the human body holds a full t

Updated on:December 22,2023 10

One in six premenopausal early breast cancer patients do not adhere to hormonal therapy

byEuropean Society for Medical OncologyLead author Barbara Pistilli, a medical oncologist at Institut Gustave Roussy, Villejuif, France. Credit: European Society for Medical OncologyNearly one i

Updated on: December 18,2023 20

One in six premenopausal early breast cancer patients do not adhere to hormonal therapy

byEuropean Society for Medical OncologyLead author Barbara Pistilli, a medical oncologist at Institut Gustave Roussy, Villejuif, France. Credit: European Society for Medical OncologyNearly one i

Updated on:December 18,2023 20

Lung cancer study finds new target for treatment resistance after EGFR inhibitors

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers at The University of Texas MD Anderson Cancer Center have identified CD70 as being highly expressed

Updated on: December 22,2023 10

Lung cancer study finds new target for treatment resistance after EGFR inhibitors

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers at The University of Texas MD Anderson Cancer Center have identified CD70 as being highly expressed

Updated on:December 22,2023 10

Ice baths are popular with celebrities, but what are the health benefits, if any—and risks?

by Erin Kayata,Northeastern UniversityCredit: Unsplash/CC0 Public DomainWhen it comes to workout cool-downs, some people take the idea seriously by dunking themselves in an ice bath. Celebrities

Updated on: March 25,2024 17

Ice baths are popular with celebrities, but what are the health benefits, if any—and risks?

by Erin Kayata,Northeastern UniversityCredit: Unsplash/CC0 Public DomainWhen it comes to workout cool-downs, some people take the idea seriously by dunking themselves in an ice bath. Celebrities

Updated on:March 25,2024 17

Phase I clinical trial of the first drug to successfully inhibit the MYC gene that drives many common cancers

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainResearchers report that a drug targeting the cancer-causing gene MYC inhibits the function of the gene in

Updated on: December 20,2023 16

Phase I clinical trial of the first drug to successfully inhibit the MYC gene that drives many common cancers

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainResearchers report that a drug targeting the cancer-causing gene MYC inhibits the function of the gene in

Updated on:December 20,2023 16

Liquid biopsy predicts immunotherapy response and toxicity in patients with advanced lung cancer

byJohns Hopkins University School of MedicineLiquid biopsy to study genetic material shed into bloodstream helps predict response to immunotherapy. Credit: Valsamo "Elsa" Anagnostou us

Updated on: January 25,2024 14

Liquid biopsy predicts immunotherapy response and toxicity in patients with advanced lung cancer

byJohns Hopkins University School of MedicineLiquid biopsy to study genetic material shed into bloodstream helps predict response to immunotherapy. Credit: Valsamo "Elsa" Anagnostou us

Updated on:January 25,2024 14

What you need to know after a breast cancer diagnosis

by Robin FosterBreast cancer strikes 1 in 8 women in the United States, but being diagnosed with the disease can still make you feel alone.To cope with such devastating news, breast cancer surgeons fr

Updated on: October 24,2024 0

What you need to know after a breast cancer diagnosis

by Robin FosterBreast cancer strikes 1 in 8 women in the United States, but being diagnosed with the disease can still make you feel alone.To cope with such devastating news, breast cancer surgeons fr

Updated on:October 24,2024 0

Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co

Updated on: December 28,2023 15

Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co

Updated on:December 28,2023 15

Two common types of antidepressants found to be safe for most stroke survivors

by American Heart AssociationCredit: Unsplash/CC0 Public DomainMost stroke survivors were able to safely take two types of common antidepressants, according to a preliminary study to be presented

Updated on: May 06,2024 15

Two common types of antidepressants found to be safe for most stroke survivors

by American Heart AssociationCredit: Unsplash/CC0 Public DomainMost stroke survivors were able to safely take two types of common antidepressants, according to a preliminary study to be presented

Updated on:May 06,2024 15

Colonoscopies among the young are on the rise

by Ernie MundellColon cancers are increasing among younger Americans, so much so that experts advised in 2021 that colonoscopy screening begins at the age of 45, not 50 as had been previously recommen

Updated on: October 26,2024 0

Colonoscopies among the young are on the rise

by Ernie MundellColon cancers are increasing among younger Americans, so much so that experts advised in 2021 that colonoscopy screening begins at the age of 45, not 50 as had been previously recommen

Updated on:October 26,2024 0

Black women with breast cancer may have worse outcomes than peers despite similar genetic recurrence scores

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainNon-Hispanic Black women with hormone receptor (HR)-positive/HER2-negative, lymph node-positive breast cancer had wors

Updated on: December 24,2023 10

Black women with breast cancer may have worse outcomes than peers despite similar genetic recurrence scores

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainNon-Hispanic Black women with hormone receptor (HR)-positive/HER2-negative, lymph node-positive breast cancer had wors

Updated on:December 24,2023 10