Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen

Updated on: December 25,2023

Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen

Updated on:December 25,2023

Protein transformation drives cancer development

byNorthwestern UniversityMitochondria. Credit: Wikipedia commonsA change in function in a mitochondrial antioxidant protein increases stem cell gene expression that promotes the development of m

Updated on: December 20,2023

Protein transformation drives cancer development

byNorthwestern UniversityMitochondria. Credit: Wikipedia commonsA change in function in a mitochondrial antioxidant protein increases stem cell gene expression that promotes the development of m

Updated on:December 20,2023

Scientists discover mucus allows young pancreatic cancer cells to grow but may also prevent a deadly transformation

FEBRUARY 28, 2024by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of a mouse's early-stage pancreatic tumor. CSHL scientists discovered that early pancreatic cancer cells depend

Updated on: March 15,2024

Scientists discover mucus allows young pancreatic cancer cells to grow but may also prevent a deadly transformation

FEBRUARY 28, 2024by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of a mouse's early-stage pancreatic tumor. CSHL scientists discovered that early pancreatic cancer cells depend

Updated on:March 15,2024

Major response to immunotherapy in early-stage mismatch repair deficient colon cancer

byEuropean Society for Medical OncologyCredit:Annals of OncologyPre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major patho

Updated on: December 18,2023

Major response to immunotherapy in early-stage mismatch repair deficient colon cancer

byEuropean Society for Medical OncologyCredit:Annals of OncologyPre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major patho

Updated on:December 18,2023

Study shows which patients with advanced prostate cancer will benefit from chemotherapy

by University College LondonProstate cancer cells. Credit: NIH Image GalleryResearchers have recommended changes to how cancer patients are treated, after a new UCL-led study discovered that chem

Updated on: April 03,2024

Study shows which patients with advanced prostate cancer will benefit from chemotherapy

by University College LondonProstate cancer cells. Credit: NIH Image GalleryResearchers have recommended changes to how cancer patients are treated, after a new UCL-led study discovered that chem

Updated on:April 03,2024

Model illuminates environmental cues that may contribute to breast cancer recurrence

by Karen B. Roberts,University of DelawareUniversity of Delaware post-doctoral researcher Lina Pradham loads a protocol and plate into a bioprinter made by Inventia. Called the RASTRUM, the Inve

Updated on: December 22,2023

Model illuminates environmental cues that may contribute to breast cancer recurrence

by Karen B. Roberts,University of DelawareUniversity of Delaware post-doctoral researcher Lina Pradham loads a protocol and plate into a bioprinter made by Inventia. Called the RASTRUM, the Inve

Updated on:December 22,2023

A case for routine evaluation of HER2 expression in ductal carcinoma in situ

by Impact JournalsCredit: Unsplash/CC0 Public DomainA new editorial paper was published inOncoscienceand is titled "HER2 expression should be routinely evaluated in DCIS to avoid unde

Updated on: December 20,2023

A case for routine evaluation of HER2 expression in ductal carcinoma in situ

by Impact JournalsCredit: Unsplash/CC0 Public DomainA new editorial paper was published inOncoscienceand is titled "HER2 expression should be routinely evaluated in DCIS to avoid unde

Updated on:December 20,2023

Less than half of pregnant women get the flu shot: New data from UPMC Children's might change that

by Abby Mackey, Pittsburgh Post-GazetteCredit: Unsplash/CC0 Public DomainJohn Williams knows the risks associated with riding motorcycles, but they don't deter him. Neither do warnings from physic

Updated on: March 25,2024

Less than half of pregnant women get the flu shot: New data from UPMC Children's might change that

by Abby Mackey, Pittsburgh Post-GazetteCredit: Unsplash/CC0 Public DomainJohn Williams knows the risks associated with riding motorcycles, but they don't deter him. Neither do warnings from physic

Updated on:March 25,2024

Why are so many Australians taking antidepressants?

by Jon Jureidini,The ConversationCredit: Pixabay/CC0 Public DomainAroundone in seven Australianstake antidepressants; more than3.5 millionof us had them dispensed in 2021

Updated on: May 07,2024

Why are so many Australians taking antidepressants?

by Jon Jureidini,The ConversationCredit: Pixabay/CC0 Public DomainAroundone in seven Australianstake antidepressants; more than3.5 millionof us had them dispensed in 2021

Updated on:May 07,2024

Novel treatment regimen for FLT3-mutated acute myeloid leukemia shows promise in new study

by Roswell Park Comprehensive Cancer CenterAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainUp to 30% of patients newly diagnosed with acute myeloid leukemia (AML) have an FLT3 gene

Updated on: March 22,2024

Novel treatment regimen for FLT3-mutated acute myeloid leukemia shows promise in new study

by Roswell Park Comprehensive Cancer CenterAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainUp to 30% of patients newly diagnosed with acute myeloid leukemia (AML) have an FLT3 gene

Updated on:March 22,2024

Study offers a potential strategy to improve T cell therapy in solid tumors

byPerelman School of Medicine at the University of PennsylvaniaRegnase-1 and Roquin-1 double knockout alters the activation profile of resting engineered T cells. (A) Healthy human donor T cells

Updated on: December 22,2023

Study offers a potential strategy to improve T cell therapy in solid tumors

byPerelman School of Medicine at the University of PennsylvaniaRegnase-1 and Roquin-1 double knockout alters the activation profile of resting engineered T cells. (A) Healthy human donor T cells

Updated on:December 22,2023

Mediterranean diet improves immunotherapy response rates and progression-free survival in advanced melanoma

by United European GastroenterologyCredit: Unsplash/CC0 Public DomainEating a Mediterranean diet rich in fiber, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunoth

Updated on: December 20,2023

Mediterranean diet improves immunotherapy response rates and progression-free survival in advanced melanoma

by United European GastroenterologyCredit: Unsplash/CC0 Public DomainEating a Mediterranean diet rich in fiber, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunoth

Updated on:December 20,2023