Pioneering mRNA-4157 Cancer Vaccines: Personalized Immunotherapy for Targeted Treatment

Updated on: June 13,2024 1

Pioneering mRNA-4157 Cancer Vaccines: Personalized Immunotherapy for Targeted Treatment

Updated on:June 13,2024 1

Two drugs reverse a key pancreatic cancer step in the lab

byUniversity of FloridaReversal of ADM by TSA in primary human acinar cultures. Primary, human acini were cultured in Matrigel on glass chamber slides for 5 days. On day 5 of culture, 500 nM of

Updated on: December 28,2023 10

Two drugs reverse a key pancreatic cancer step in the lab

byUniversity of FloridaReversal of ADM by TSA in primary human acinar cultures. Primary, human acini were cultured in Matrigel on glass chamber slides for 5 days. On day 5 of culture, 500 nM of

Updated on:December 28,2023 10

Cancer patients who don't respond to immunotherapy may lack crucial immune cells

byWashington University School of MedicineCD5+ DC frequency was reduced in tumor-affected lymph nodes, and their presence correlated with greater patient survival in multiple tumors. CD5+D

Updated on: December 20,2023 12

Cancer patients who don't respond to immunotherapy may lack crucial immune cells

byWashington University School of MedicineCD5+ DC frequency was reduced in tumor-affected lymph nodes, and their presence correlated with greater patient survival in multiple tumors. CD5+D

Updated on:December 20,2023 12

Life-threatening side effects of novel cancer immunotherapies could be treatable

byKarolinska InstitutetLaboratory tests after immune checkpoint inhibitor (ICI) treatment in a patient with metastatic renal cell carcinoma. (A) Routine blood tests for the indicated markers at

Updated on: January 15,2024 12

Life-threatening side effects of novel cancer immunotherapies could be treatable

byKarolinska InstitutetLaboratory tests after immune checkpoint inhibitor (ICI) treatment in a patient with metastatic renal cell carcinoma. (A) Routine blood tests for the indicated markers at

Updated on:January 15,2024 12

Using single-cell sequencing to reveal processes involved in ovarian and breast cancers

by Bob Yirka , Medical XpressStudy overview. Experimental and cohort design. Single-cell genomes, transcriptomes and long-read sequencing libraries were generated from isogenic 184-hTERT cell lines (W

Updated on: December 28,2023 15

Using single-cell sequencing to reveal processes involved in ovarian and breast cancers

by Bob Yirka , Medical XpressStudy overview. Experimental and cohort design. Single-cell genomes, transcriptomes and long-read sequencing libraries were generated from isogenic 184-hTERT cell lines (W

Updated on:December 28,2023 15

Immunotherapy before surgery induces complete response in more than half of patients with common skin cancer

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainIn an international, multicenter Phase II clinical trial led by The University of Texas MD Anderson Cancer Center, 63.3

Updated on: February 01,2024 15

Immunotherapy before surgery induces complete response in more than half of patients with common skin cancer

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainIn an international, multicenter Phase II clinical trial led by The University of Texas MD Anderson Cancer Center, 63.3

Updated on:February 01,2024 15

Bacterium may decrease effectiveness of immunotherapy

by Béatrice St-Cyr-Leroux,University of MontrealAssociation between the H. pylori seropositivity status and clinical outcomes in 97 patients with advanced melanoma. A. Stacked barplot between H.

Updated on: January 10,2024 9

Bacterium may decrease effectiveness of immunotherapy

by Béatrice St-Cyr-Leroux,University of MontrealAssociation between the H. pylori seropositivity status and clinical outcomes in 97 patients with advanced melanoma. A. Stacked barplot between H.

Updated on:January 10,2024 9

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

Updated on: January 21,2024 16

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

Updated on:January 21,2024 16

Adherence to quality indicators low in chronic myeloid leukemia

by Elana Gotkine HealthDay ReporterFor newly diagnosed chronic-phase chronic myeloid leukemia (CML) patients, adherence to guideline-based quality indicators is low, according to a study published onl

Updated on: December 28,2023 6

Adherence to quality indicators low in chronic myeloid leukemia

by Elana Gotkine HealthDay ReporterFor newly diagnosed chronic-phase chronic myeloid leukemia (CML) patients, adherence to guideline-based quality indicators is low, according to a study published onl

Updated on:December 28,2023 6

Sleep disturbances are underappreciated in prostate cancer survivorship

by Tim Baker, Prostate Cancer Foundation of AustraliaCredit: CC0 Public DomainWe all got the memo that sleep is foundational for good health, right?Yet, it remains easy to overlook the importance of&n

Updated on: January 04,2024 13

Sleep disturbances are underappreciated in prostate cancer survivorship

by Tim Baker, Prostate Cancer Foundation of AustraliaCredit: CC0 Public DomainWe all got the memo that sleep is foundational for good health, right?Yet, it remains easy to overlook the importance of&n

Updated on:January 04,2024 13

Bendamustine prior to CAR T-cell therapy in patients with refractory large B-cell lymphoma: Poorer treatment outcomes

byVall d'Hebron Institute of OncologyCredit: Pixabay/CC0 Public DomainTreatment with bendamustine prior to CAR T-cell therapy in patients with refractory large B-cell lymphoma associates wit

Updated on: December 28,2023 8

Bendamustine prior to CAR T-cell therapy in patients with refractory large B-cell lymphoma: Poorer treatment outcomes

byVall d'Hebron Institute of OncologyCredit: Pixabay/CC0 Public DomainTreatment with bendamustine prior to CAR T-cell therapy in patients with refractory large B-cell lymphoma associates wit

Updated on:December 28,2023 8

Addition of durvalumab, bevacizumab to TACE beneficial in liver cancer

by Elana GotkineFor patients with embolization-eligible unresectable hepatocellular carcinoma (uHCC), the addition of durvalumab (D) and bevacizumab (B) to transarterial chemoembolization (TACE) impro

Updated on: March 22,2024 12

Addition of durvalumab, bevacizumab to TACE beneficial in liver cancer

by Elana GotkineFor patients with embolization-eligible unresectable hepatocellular carcinoma (uHCC), the addition of durvalumab (D) and bevacizumab (B) to transarterial chemoembolization (TACE) impro

Updated on:March 22,2024 12