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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
Sub Categories on Oncology
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Cancer screening and detection remain below prepandemic levels

Cancer screening and detection remain below prepandemic levels

At the end of 2021, population-based screening and diagnosis remained below prepandemic levels for breast, cervical, and colorectal cancers, according to a research letter published online Nov. 17 in&

Cancer screening and detection remain below prepandemic levels

At the end of 2021, population-based screening and diagnosis remained below prepandemic levels for breast, cervical, and colorectal cancers, according to a research letter published online Nov. 17 in&
Patients with high-risk melanoma had better quality of life on pembrolizumab than on standard immunotherapy regimens

Patients with high-risk melanoma had better quality of life on pembrolizumab than on standard immunotherapy regimens

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainPatients with high-risk stage III-IV melanoma who received pembrolizumab after their surgery reported a better quality of life than pati

Patients with high-risk melanoma had better quality of life on pembrolizumab than on standard immunotherapy regimens

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainPatients with high-risk stage III-IV melanoma who received pembrolizumab after their surgery reported a better quality of life than pati
New targets in the fight against pancreatic cancer

New targets in the fight against pancreatic cancer

by Tokyo Medical and Dental UniversityTop, SETD1A, directly recruited to the RUVBL1 promoter, enhances RUVBL1 gene expression by increasing H3K4me3 levels in pancreatic cancer cells. Bottom, High co-e

New targets in the fight against pancreatic cancer

by Tokyo Medical and Dental UniversityTop, SETD1A, directly recruited to the RUVBL1 promoter, enhances RUVBL1 gene expression by increasing H3K4me3 levels in pancreatic cancer cells. Bottom, High co-e
Preoperative immunotherapy for mesothelioma shows favorable outcomes

Preoperative immunotherapy for mesothelioma shows favorable outcomes

by Dipali Pathak,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainIn a study published recently in the journalClinical Cancer Research, researchers at Baylor College of Medicine

Preoperative immunotherapy for mesothelioma shows favorable outcomes

by Dipali Pathak,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainIn a study published recently in the journalClinical Cancer Research, researchers at Baylor College of Medicine
CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A: Study

CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A: Study

by Higher Education PressCoactivator-associated arginine methyltransferase 1 (CARM1) was recruited by hypoxia-inducible factor 1 subunit alpha (HIF1A) to form a complex and transactivate CDK4 and HIF1

CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A: Study

by Higher Education PressCoactivator-associated arginine methyltransferase 1 (CARM1) was recruited by hypoxia-inducible factor 1 subunit alpha (HIF1A) to form a complex and transactivate CDK4 and HIF1
Molecular tumor boards improve outcomes for patients with advanced cancer

Molecular tumor boards improve outcomes for patients with advanced cancer

by Elizabeth Chapin,University of KentuckyWaterfall plot detailing individual PFS ratio (PFS2/PFS1) values for patients treated with second-line or greater-line MTB-directed therapy (cohort 1; n

Molecular tumor boards improve outcomes for patients with advanced cancer

by Elizabeth Chapin,University of KentuckyWaterfall plot detailing individual PFS ratio (PFS2/PFS1) values for patients treated with second-line or greater-line MTB-directed therapy (cohort 1; n
Study offers a potential strategy to improve T cell therapy in solid tumors

Study offers a potential strategy to improve T cell therapy in solid tumors

byPerelman School of Medicine at the University of PennsylvaniaRegnase-1 and Roquin-1 double knockout alters the activation profile of resting engineered T cells. (A) Healthy human donor T cells

Study offers a potential strategy to improve T cell therapy in solid tumors

byPerelman School of Medicine at the University of PennsylvaniaRegnase-1 and Roquin-1 double knockout alters the activation profile of resting engineered T cells. (A) Healthy human donor T cells
Ultrasensitive blood test detects 'pan-cancer' biomarker

Ultrasensitive blood test detects 'pan-cancer' biomarker

byMass General BrighamCirculating ORF1p levels in lung cancer patient cohort, as classified by (A) disease subtype, (B) gender, and (C) smoking status. Blue dashed line indicates the assay limit

Ultrasensitive blood test detects 'pan-cancer' biomarker

byMass General BrighamCirculating ORF1p levels in lung cancer patient cohort, as classified by (A) disease subtype, (B) gender, and (C) smoking status. Blue dashed line indicates the assay limit
Gene loss enhances metastasis and cancer progression

Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen

Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen
Model illuminates environmental cues that may contribute to breast cancer recurrence

Model illuminates environmental cues that may contribute to breast cancer recurrence

by Karen B. Roberts,University of DelawareUniversity of Delaware post-doctoral researcher Lina Pradham loads a protocol and plate into a bioprinter made by Inventia. Called the RASTRUM, the Inve

Model illuminates environmental cues that may contribute to breast cancer recurrence

by Karen B. Roberts,University of DelawareUniversity of Delaware post-doctoral researcher Lina Pradham loads a protocol and plate into a bioprinter made by Inventia. Called the RASTRUM, the Inve
Genetics predict type 2 diabetes risk and disparities in childhood cancer survivors

Genetics predict type 2 diabetes risk and disparities in childhood cancer survivors

bySt. Jude Children's Research HospitalCredit: CC0 Public DomainSurvivors of childhood cancer are at increased risk for cardiovascular disease, for which a risk factor is their greater preva

Genetics predict type 2 diabetes risk and disparities in childhood cancer survivors

bySt. Jude Children's Research HospitalCredit: CC0 Public DomainSurvivors of childhood cancer are at increased risk for cardiovascular disease, for which a risk factor is their greater preva