Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on: February 20,2024

Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on:February 20,2024

Epigenetic therapy worth pursuing in hormone receptor positive advanced breast cancer

byEuropean Society for Medical OncologyCredit: CC0 Public DomainEpigenetic therapy with histone deacetylase (HDAC) inhibitors is worth pursuing in hormone receptor positive advanced breast cance

Updated on: December 18,2023

Epigenetic therapy worth pursuing in hormone receptor positive advanced breast cancer

byEuropean Society for Medical OncologyCredit: CC0 Public DomainEpigenetic therapy with histone deacetylase (HDAC) inhibitors is worth pursuing in hormone receptor positive advanced breast cance

Updated on:December 18,2023

Proposed lung cancer screening guideline could eliminate racial disparities, allow for early detection

by Liz Murphy,Massachusetts General HospitalDistribution of smoking duration (years), smoking intensity (cigarettes per day), and pack-year smoking history among SCCS participants diagnosed with

Updated on: August 27,2024

Proposed lung cancer screening guideline could eliminate racial disparities, allow for early detection

by Liz Murphy,Massachusetts General HospitalDistribution of smoking duration (years), smoking intensity (cigarettes per day), and pack-year smoking history among SCCS participants diagnosed with

Updated on:August 27,2024

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......

Updated on: May 29,2024

CAR-T Therapy Under Scrutiny: The Emerging Risk of Secondary Malignant Tumors

CAR-T therapy has long been an effective treatment for hematological cancers such as leukemia and lymphoma. However, some patients have developed secondary malignant tumors after undergoing CAR-T ......

Updated on:May 29,2024

A silent killer, liver cancer prompts race to improve organ replacements

by Anthony King,Horizon: The EU Research & Innovation MagazineBioprinter from Organtrans. Credit: © Gilles WederWith the only cure for liver cancer often being a transplantation, scientists

Updated on: December 22,2023

A silent killer, liver cancer prompts race to improve organ replacements

by Anthony King,Horizon: The EU Research & Innovation MagazineBioprinter from Organtrans. Credit: © Gilles WederWith the only cure for liver cancer often being a transplantation, scientists

Updated on:December 22,2023

Cellular 'waste product' rejuvenates cancer-fighting immune cells

byUT Southwestern Medical CenterUT Southwestern Simmons Cancer Center found that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that figh

Updated on: January 10,2024

Cellular 'waste product' rejuvenates cancer-fighting immune cells

byUT Southwestern Medical CenterUT Southwestern Simmons Cancer Center found that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that figh

Updated on:January 10,2024

Colonoscopy is the most comprehensive screening for colorectal cancer, despite flawed interpretations of a new study

by Franklin G. Berger,The ConversationCredit: American College of GastroenterologyA recently published study in a high-profile medical journal appeared to call into questionthe efficacy of

Updated on: December 26,2023

Colonoscopy is the most comprehensive screening for colorectal cancer, despite flawed interpretations of a new study

by Franklin G. Berger,The ConversationCredit: American College of GastroenterologyA recently published study in a high-profile medical journal appeared to call into questionthe efficacy of

Updated on:December 26,2023

Quantitative pathologic analysis may help predict prognosis in colorectal cancer

The quantitative segmentation algorithm (QuantCRC) may improve the prediction of prognosis in colorectal cancer (CRC), according to a study published online Aug. 16 inGastroenterology.Reetesh K.

Updated on: December 20,2023

Quantitative pathologic analysis may help predict prognosis in colorectal cancer

The quantitative segmentation algorithm (QuantCRC) may improve the prediction of prognosis in colorectal cancer (CRC), according to a study published online Aug. 16 inGastroenterology.Reetesh K.

Updated on:December 20,2023

How cellular plasticity drives cancer metastasis

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainAbout 90% of deaths from cancer are a result of metastasis—that is, from cancer's ability to spread from

Updated on: April 28,2024

How cellular plasticity drives cancer metastasis

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainAbout 90% of deaths from cancer are a result of metastasis—that is, from cancer's ability to spread from

Updated on:April 28,2024

The interaction between glucose and DDX21 in tissue differentiation and cancer metabolism

Updated on: August 03,2024

The interaction between glucose and DDX21 in tissue differentiation and cancer metabolism

Updated on:August 03,2024

New mechanism of radioresistance formation shown in lung adenocarcinoma

by Zhang Nannan,Chinese Academy of SciencesGOLPH3 mediates radioresistance formation of lung adenocarcinoma. Credit: Kong PeizhongA research team led by Prof. Han Wei from the Hefei Institutes o

Updated on: December 22,2023

New mechanism of radioresistance formation shown in lung adenocarcinoma

by Zhang Nannan,Chinese Academy of SciencesGOLPH3 mediates radioresistance formation of lung adenocarcinoma. Credit: Kong PeizhongA research team led by Prof. Han Wei from the Hefei Institutes o

Updated on:December 22,2023

Protein transformation drives cancer development

byNorthwestern UniversityMitochondria. Credit: Wikipedia commonsA change in function in a mitochondrial antioxidant protein increases stem cell gene expression that promotes the development of m

Updated on: December 20,2023

Protein transformation drives cancer development

byNorthwestern UniversityMitochondria. Credit: Wikipedia commonsA change in function in a mitochondrial antioxidant protein increases stem cell gene expression that promotes the development of m

Updated on:December 20,2023