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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Blood-based biomarker may redefine future treatment for advanced melanoma

Blood-based biomarker may redefine future treatment for advanced melanoma

byElsevierCirculating tumor DNA (ctDNA) correlates with radiology disease assessment and patient outcome. For patient A, biomarkers in their blood decreased over time and the radiology showed th

Blood-based biomarker may redefine future treatment for advanced melanoma

byElsevierCirculating tumor DNA (ctDNA) correlates with radiology disease assessment and patient outcome. For patient A, biomarkers in their blood decreased over time and the radiology showed th
Comparison of FDG-PET/CT and CT for treatment evaluation of patients with unresectable malignant pleural mesothelioma

Comparison of FDG-PET/CT and CT for treatment evaluation of patients with unresectable malignant pleural mesothelioma

by Impact Journals LLCEpithelioid MPM, stage IIIB (cT4N0M0), woman, 64 years old. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28594A new research paper titled "Comparison of FDG

Comparison of FDG-PET/CT and CT for treatment evaluation of patients with unresectable malignant pleural mesothelioma

by Impact Journals LLCEpithelioid MPM, stage IIIB (cT4N0M0), woman, 64 years old. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28594A new research paper titled "Comparison of FDG
Molecular tumor boards improve outcomes for patients with advanced cancer

Molecular tumor boards improve outcomes for patients with advanced cancer

by Elizabeth Chapin,University of KentuckyWaterfall plot detailing individual PFS ratio (PFS2/PFS1) values for patients treated with second-line or greater-line MTB-directed therapy (cohort 1; n

Molecular tumor boards improve outcomes for patients with advanced cancer

by Elizabeth Chapin,University of KentuckyWaterfall plot detailing individual PFS ratio (PFS2/PFS1) values for patients treated with second-line or greater-line MTB-directed therapy (cohort 1; n
Study reveals why testicular cancer is so responsive to chemo

Study reveals why testicular cancer is so responsive to chemo

by Cornell UniversityA low magnification image of a germ cell tumor, called a teratocarcinoma, from a new mouse model developed to study testicular cancer. A cluster of cancer stem cells, termed

Study reveals why testicular cancer is so responsive to chemo

by Cornell UniversityA low magnification image of a germ cell tumor, called a teratocarcinoma, from a new mouse model developed to study testicular cancer. A cluster of cancer stem cells, termed
Structural insights reveal how SPOP protein contributes to cancer

Structural insights reveal how SPOP protein contributes to cancer

bySt. Jude Children's Research HospitalL to R: L to R: Brian O’Flynn, Ph.D., Matthew Cuneo, Ph.D., and Tanja Mittag, Ph.D. Credit: St. Jude Children's Research HospitalSPOP is the most m

Structural insights reveal how SPOP protein contributes to cancer

bySt. Jude Children's Research HospitalL to R: L to R: Brian O’Flynn, Ph.D., Matthew Cuneo, Ph.D., and Tanja Mittag, Ph.D. Credit: St. Jude Children's Research HospitalSPOP is the most m
New therapeutic strategy for chemotherapy resistance in ovarian cancer

New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste

New therapeutic strategy for chemotherapy resistance in ovarian cancer

byThe Wistar InstituteDr. Rugang Zhang. Credit: The Wistar InstituteA study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of ste
Quantitative pathologic analysis may help predict prognosis in colorectal cancer

Quantitative pathologic analysis may help predict prognosis in colorectal cancer

The quantitative segmentation algorithm (QuantCRC) may improve the prediction of prognosis in colorectal cancer (CRC), according to a study published online Aug. 16 inGastroenterology.Reetesh K.

Quantitative pathologic analysis may help predict prognosis in colorectal cancer

The quantitative segmentation algorithm (QuantCRC) may improve the prediction of prognosis in colorectal cancer (CRC), according to a study published online Aug. 16 inGastroenterology.Reetesh K.
One in six premenopausal early breast cancer patients do not adhere to hormonal therapy

One in six premenopausal early breast cancer patients do not adhere to hormonal therapy

byEuropean Society for Medical OncologyLead author Barbara Pistilli, a medical oncologist at Institut Gustave Roussy, Villejuif, France. Credit: European Society for Medical OncologyNearly one i

One in six premenopausal early breast cancer patients do not adhere to hormonal therapy

byEuropean Society for Medical OncologyLead author Barbara Pistilli, a medical oncologist at Institut Gustave Roussy, Villejuif, France. Credit: European Society for Medical OncologyNearly one i
Study reveals key factors in surgeons' opioid prescribing patterns

Study reveals key factors in surgeons' opioid prescribing patterns

by American College of SurgeonsCredit: Pixabay/CC0 Public DomainResearchers revealed new insights into the patterns and predictors of opioid prescribing after surgery in a comprehensive county-le

Study reveals key factors in surgeons' opioid prescribing patterns

by American College of SurgeonsCredit: Pixabay/CC0 Public DomainResearchers revealed new insights into the patterns and predictors of opioid prescribing after surgery in a comprehensive county-le
Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co

Peripheral blood haplo-SCT feasible for leukemia patients 70 years and older

by Elana GotkineFor patients with acute myeloid leukemia (AML)/myelodysplastic syndromes (MDS) aged 70 years and older, haploidentical stem cell transplantation (Haplo-SCT) using a nonmyeloablative co
Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was
Scientists discover a new way to prevent secondary breast cancer

Scientists discover a new way to prevent secondary breast cancer

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainScientists have discovered why breast cancer cells that have spread to the lungs may "wake up" following years of sleep,

Scientists discover a new way to prevent secondary breast cancer

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainScientists have discovered why breast cancer cells that have spread to the lungs may "wake up" following years of sleep,