Study offers a potential strategy to improve T cell therapy in solid tumors

byPerelman School of Medicine at the University of PennsylvaniaRegnase-1 and Roquin-1 double knockout alters the activation profile of resting engineered T cells. (A) Healthy human donor T cells

Updated on: December 22,2023

Study offers a potential strategy to improve T cell therapy in solid tumors

byPerelman School of Medicine at the University of PennsylvaniaRegnase-1 and Roquin-1 double knockout alters the activation profile of resting engineered T cells. (A) Healthy human donor T cells

Updated on:December 22,2023

Drug used for cocaine addiction may pave way for new treatment of advanced colon cancer

by University of OttawaMulti-omic characterization of VXN cancer-selective effect on cell functions. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00727-yA new, cutting-edge stu

Updated on: May 11,2024

Drug used for cocaine addiction may pave way for new treatment of advanced colon cancer

by University of OttawaMulti-omic characterization of VXN cancer-selective effect on cell functions. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00727-yA new, cutting-edge stu

Updated on:May 11,2024

Uptake of HIV prevention medication doubles with mix of digital health interventions, study finds

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainA UCLA Health-led study found a combination of interventions of one-on-one telehealth coaching, peer support forums, and a

Updated on: May 16,2024

Uptake of HIV prevention medication doubles with mix of digital health interventions, study finds

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainA UCLA Health-led study found a combination of interventions of one-on-one telehealth coaching, peer support forums, and a

Updated on:May 16,2024

'Olive oil' drug shows early promise for some brain cancer patients

by Institute of Cancer ResearchMechanism of action of 2-OHOA. (1) 2-OHOA regulates the cell membrane composition by both direct incorporation into the lipid bilayer and regulation of important li

Updated on: April 02,2024

'Olive oil' drug shows early promise for some brain cancer patients

by Institute of Cancer ResearchMechanism of action of 2-OHOA. (1) 2-OHOA regulates the cell membrane composition by both direct incorporation into the lipid bilayer and regulation of important li

Updated on:April 02,2024

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on: January 08,2024

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on:January 08,2024

Phase I clinical trial of the first drug to successfully inhibit the MYC gene that drives many common cancers

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainResearchers report that a drug targeting the cancer-causing gene MYC inhibits the function of the gene in

Updated on: December 20,2023

Phase I clinical trial of the first drug to successfully inhibit the MYC gene that drives many common cancers

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainResearchers report that a drug targeting the cancer-causing gene MYC inhibits the function of the gene in

Updated on:December 20,2023

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Updated on: December 25,2023

Genes reveal kidney cancer's risk of recurrence

byMcGill UniversityDisease-Free Survival outcomes amongst genomic groups when applied to the 247 VHL mutated ccRCCs from the TCGA dataset. Credit:Clinical Cancer Research(2023). DOI:

Updated on:December 25,2023

Transistors help identify cancer cell markers

by Tokyo Medical and Dental UniversityIon-sensitive field effect transistors detect breast cancer cells expressing EGFR when bound by an antibody linked to a chemical reporter. Credit: Department of B

Updated on: December 26,2023

Transistors help identify cancer cell markers

by Tokyo Medical and Dental UniversityIon-sensitive field effect transistors detect breast cancer cells expressing EGFR when bound by an antibody linked to a chemical reporter. Credit: Department of B

Updated on:December 26,2023

Trial demonstrates one-year progression-free survival in 94% of patients with stage 3 or 4 classic Hodgkin lymphoma

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainA Phase 3 trial has demonstrated that patients with advanced stage (3 or 4) classic Hodgkin lymphoma who underwent initial treatment wi

Updated on: January 04,2024

Trial demonstrates one-year progression-free survival in 94% of patients with stage 3 or 4 classic Hodgkin lymphoma

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainA Phase 3 trial has demonstrated that patients with advanced stage (3 or 4) classic Hodgkin lymphoma who underwent initial treatment wi

Updated on:January 04,2024

3D genome features point to possible therapeutic target for aggressive and deadly pediatric brain tumors

by Fabienne Landry,McGill University Health CentreCredit:Cell(2024). DOI: 10.1016/j.cell.2024.06.023Posterior fossa group A (PFA) ependymoma are rare, treatment-resistant pediatric t

Updated on: July 11,2024

3D genome features point to possible therapeutic target for aggressive and deadly pediatric brain tumors

by Fabienne Landry,McGill University Health CentreCredit:Cell(2024). DOI: 10.1016/j.cell.2024.06.023Posterior fossa group A (PFA) ependymoma are rare, treatment-resistant pediatric t

Updated on:July 11,2024

Regular exercise should be part of cancer care for all patients

byEuropean Society for Medical OncologyQuality of life scores before and after chemotherapy in active and inactive patients. Credit: European Society for Medical OncologyIncluding exercise or sp

Updated on: December 18,2023

Regular exercise should be part of cancer care for all patients

byEuropean Society for Medical OncologyQuality of life scores before and after chemotherapy in active and inactive patients. Credit: European Society for Medical OncologyIncluding exercise or sp

Updated on:December 18,2023

A blood sample 24 hours after the start of chemotherapy can predict survival

byUniversity of BergenMass cytometry analysis of early response evaluation by single-cell signaling to profile.aPeripheral blood samples were collected from 32 AML patients treated w

Updated on: December 25,2023

A blood sample 24 hours after the start of chemotherapy can predict survival

byUniversity of BergenMass cytometry analysis of early response evaluation by single-cell signaling to profile.aPeripheral blood samples were collected from 32 AML patients treated w

Updated on:December 25,2023