A new mechanism of drug resistance discovered for breast cancer

by Universita Cattolica del Sacro CuoreEmergence of CSCs following IFN-I treatment.a, Multiparametric flow cytometry analysis of the illustrated CSC surface markers in MCA205 and AT3 cells treat

Updated on: December 21,2023 13

A new mechanism of drug resistance discovered for breast cancer

by Universita Cattolica del Sacro CuoreEmergence of CSCs following IFN-I treatment.a, Multiparametric flow cytometry analysis of the illustrated CSC surface markers in MCA205 and AT3 cells treat

Updated on:December 21,2023 13

Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

July 14, 2023Caroline SeymourHigher levels of baseline TCR clonality in peripheral blood mononuclear cells (PBMCs) and baseline IgG1 fraction in PBMCs and tumor tissue were identified in an institutio

Updated on: October 24,2023 49

Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

July 14, 2023Caroline SeymourHigher levels of baseline TCR clonality in peripheral blood mononuclear cells (PBMCs) and baseline IgG1 fraction in PBMCs and tumor tissue were identified in an institutio

Updated on:October 24,2023 49

Large study links sustained weight loss to reduced breast cancer risk

byAmerican Cancer SocietyCredit: CC0 Public DomainA large new study finds that women who lost weight after age 50 and kept it off had a lower risk of breast cancer than women whose weight remain

Updated on: December 22,2023 19

Large study links sustained weight loss to reduced breast cancer risk

byAmerican Cancer SocietyCredit: CC0 Public DomainA large new study finds that women who lost weight after age 50 and kept it off had a lower risk of breast cancer than women whose weight remain

Updated on:December 22,2023 19

Real-World Data Highlight Utility of Axi-Cel/Tisa-Cel in DLBCL

June 12, 2021Conor KillmurrayIn the first few years of their availability in the United States, axicabtagene ciloleucel and tisagenlecleucel have been used to mostly treat patients with diffuse large

Updated on: October 24,2023 2

Real-World Data Highlight Utility of Axi-Cel/Tisa-Cel in DLBCL

June 12, 2021Conor KillmurrayIn the first few years of their availability in the United States, axicabtagene ciloleucel and tisagenlecleucel have been used to mostly treat patients with diffuse large

Updated on:October 24,2023 2

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas

Updated on: January 08,2024 10

Interrupting endocrine therapy to pursue pregnancy doesn't lead to worse short-term breast cancer recurrence rates

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainBreast cancer patients who paused their endocrine therapy to try to get pregnant experienced short-term rates of breas

Updated on:January 08,2024 10

Sunitinib Elicits Improved Efficacy Vs Placebo in Malignant Pheochromocytoma/Paragangliomas

September 20, 2021Kristie L. KahlFirst-line sunitinib was found to improve efficacy compared with placebo in patients with malignant pheochromocytoma and paragangliomas.First-line sunitinib (Sut

Updated on: October 24,2023 32

Sunitinib Elicits Improved Efficacy Vs Placebo in Malignant Pheochromocytoma/Paragangliomas

September 20, 2021Kristie L. KahlFirst-line sunitinib was found to improve efficacy compared with placebo in patients with malignant pheochromocytoma and paragangliomas.First-line sunitinib (Sut

Updated on:October 24,2023 32

Healthy diets linked to better outcomes in colorectal cancer

byAmerican Cancer SocietyCredit: CC0 Public DomainColorectal cancer patients who followed healthy diets had a lower risk of death from colorectal cancer and all causes, even those who improved t

Updated on: December 18,2023 13

Healthy diets linked to better outcomes in colorectal cancer

byAmerican Cancer SocietyCredit: CC0 Public DomainColorectal cancer patients who followed healthy diets had a lower risk of death from colorectal cancer and all causes, even those who improved t

Updated on:December 18,2023 13

Maveropepimut-S Plus Pembrolizumab and Cyclophosphamide Shows Early Promise in R/R DLBCL

February 13, 2023Kristi RosaThe combination of maveropepimut-S, pembrolizumab, and intermittent low-dose cyclophosphamide elicited responses in patients with relapsed or refractory diffuse large B-cel

Updated on: October 17,2023 178

Maveropepimut-S Plus Pembrolizumab and Cyclophosphamide Shows Early Promise in R/R DLBCL

February 13, 2023Kristi RosaThe combination of maveropepimut-S, pembrolizumab, and intermittent low-dose cyclophosphamide elicited responses in patients with relapsed or refractory diffuse large B-cel

Updated on:October 17,2023 178

Radiotherapy for ductal in situ carcinoma ups mortality risk in invasive second breast cancer

(HealthDay)—For women with primary ductal carcinoma in situ (DCIS), use of radiotherapy (RT) is associated with increased rates of breast cancer-specific mortality for those women who subsequently dev

Updated on: December 22,2023 19

Radiotherapy for ductal in situ carcinoma ups mortality risk in invasive second breast cancer

(HealthDay)—For women with primary ductal carcinoma in situ (DCIS), use of radiotherapy (RT) is associated with increased rates of breast cancer-specific mortality for those women who subsequently dev

Updated on:December 22,2023 19

Adding immunotherapy to chemotherapy regimen improves survival in metastatic bladder cancer patients

byThe Mount Sinai HospitalCredit: Unsplash/CC0 Public DomainA clinical trial co-led by Mount Sinai researchers is the first to show that using chemotherapy with immunotherapy resulted in improve

Updated on: October 23,2023 164

Adding immunotherapy to chemotherapy regimen improves survival in metastatic bladder cancer patients

byThe Mount Sinai HospitalCredit: Unsplash/CC0 Public DomainA clinical trial co-led by Mount Sinai researchers is the first to show that using chemotherapy with immunotherapy resulted in improve

Updated on:October 23,2023 164

EMA Accepts Marketing Application for Odronextamab in R/R DLBCL or Follicular Lymphoma

August 17, 2023Chris RyanThe European Medicines Agency has accepted a marketing authorization application seeking the approval of odronextamab for the treatment of adult patients with relapsed/refract

Updated on: October 12,2023 6

EMA Accepts Marketing Application for Odronextamab in R/R DLBCL or Follicular Lymphoma

August 17, 2023Chris RyanThe European Medicines Agency has accepted a marketing authorization application seeking the approval of odronextamab for the treatment of adult patients with relapsed/refract

Updated on:October 12,2023 6

Treatment without hormone blockers improves outcomes in solitary prostate cancer metastases

byWolters Kluwer HealthA, Prostate specific antigen (PSA) waterfall plot for surgical metastasis-directed therapy. B, PSA waterfall plot for stereotactic body radiation therapy metastasis-direct

Updated on: December 19,2023 9

Treatment without hormone blockers improves outcomes in solitary prostate cancer metastases

byWolters Kluwer HealthA, Prostate specific antigen (PSA) waterfall plot for surgical metastasis-directed therapy. B, PSA waterfall plot for stereotactic body radiation therapy metastasis-direct

Updated on:December 19,2023 9