Trial finds that adagrasib demonstrates durable clinical activity in patients with KRAS-G12C mutations

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe oral, selective KRAS G12C inhibitor KRAS-G12C inhibitor adagrasib demonstrated durable clinical activity,

Updated on: January 04,2024 8

Trial finds that adagrasib demonstrates durable clinical activity in patients with KRAS-G12C mutations

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe oral, selective KRAS G12C inhibitor KRAS-G12C inhibitor adagrasib demonstrated durable clinical activity,

Updated on:January 04,2024 8

Examining resistance to immunotherapy in ovarian cancer

byMemorial Sloan Kettering Cancer CenterTME of HGSOC at single-cell resolution.a, Overview of the MSK SPECTRUM cohort and specimen collection workflow.b, UMAP plot of cells profiled

Updated on: December 28,2023 10

Examining resistance to immunotherapy in ovarian cancer

byMemorial Sloan Kettering Cancer CenterTME of HGSOC at single-cell resolution.a, Overview of the MSK SPECTRUM cohort and specimen collection workflow.b, UMAP plot of cells profiled

Updated on:December 28,2023 10

Great oaks grow from small acorns: Oncology is committed to doing its part for sustainability

byEuropean Society for Medical OncologySustainability will be at the heart of many discussions at theESMO Congress 2022, as illustrated by the new results and initiatives spanning cancer p

Updated on: January 08,2024 10

Great oaks grow from small acorns: Oncology is committed to doing its part for sustainability

byEuropean Society for Medical OncologySustainability will be at the heart of many discussions at theESMO Congress 2022, as illustrated by the new results and initiatives spanning cancer p

Updated on:January 08,2024 10

To rev-up CAR T-cell therapy, inhibit the SUSD2 membrane protein, study suggests

byOhio State University Medical CenterCredit: Pixabay/CC0 Public DomainInhibiting a particular protein in cancer-killing immune cells might improve the long-term effectiveness of CAR T-cell and

Updated on: January 22,2024 18

To rev-up CAR T-cell therapy, inhibit the SUSD2 membrane protein, study suggests

byOhio State University Medical CenterCredit: Pixabay/CC0 Public DomainInhibiting a particular protein in cancer-killing immune cells might improve the long-term effectiveness of CAR T-cell and

Updated on:January 22,2024 18

An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on: February 01,2024 16

An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on:February 01,2024 16

Immunotherapy after surgery found to provide significant, durable benefit for high-risk bladder patients

byThe Mount Sinai HospitalCredit: Unsplash/CC0 Public DomainImmunotherapy after surgery increased bladder cancer patients' chance of staying cancer-free compared to patients who received a p

Updated on: January 04,2024 10

Immunotherapy after surgery found to provide significant, durable benefit for high-risk bladder patients

byThe Mount Sinai HospitalCredit: Unsplash/CC0 Public DomainImmunotherapy after surgery increased bladder cancer patients' chance of staying cancer-free compared to patients who received a p

Updated on:January 04,2024 10

Survival in Primary Hemophagocytic Lymphohistiocytosis Can Be as High as 100%

February 2024Lara C. Pullen, PhDResults from a contemporary standard-of-care study of patients with primary hemophagocytic lymphohistiocytosis (pHLH) reveal that firstline etoposide-based therapy is m

Updated on: February 18,2024 11

Survival in Primary Hemophagocytic Lymphohistiocytosis Can Be as High as 100%

February 2024Lara C. Pullen, PhDResults from a contemporary standard-of-care study of patients with primary hemophagocytic lymphohistiocytosis (pHLH) reveal that firstline etoposide-based therapy is m

Updated on:February 18,2024 11

Novel inherited variants may raise risk for Hodgkin lymphoma

Novel coding and noncoding gene variants have been identified that may increase the risk for developing Hodgkin lymphoma (HL), according to a study published online Aug. 20 inBlood.Jamie E. Fler

Updated on: January 13,2024 13

Novel inherited variants may raise risk for Hodgkin lymphoma

Novel coding and noncoding gene variants have been identified that may increase the risk for developing Hodgkin lymphoma (HL), according to a study published online Aug. 20 inBlood.Jamie E. Fler

Updated on:January 13,2024 13

Study reveals aggressive prostate cancer linked to ancestral heritage

byUniversity of SydneyCredit:Nature(2022). DOI: 10.1038/s41586-022-05154-6Two pioneering studies published simultaneously today inNatureandGenome Medicine, have ide

Updated on: January 22,2024 11

Study reveals aggressive prostate cancer linked to ancestral heritage

byUniversity of SydneyCredit:Nature(2022). DOI: 10.1038/s41586-022-05154-6Two pioneering studies published simultaneously today inNatureandGenome Medicine, have ide

Updated on:January 22,2024 11

AI model using daily step counts predicts unplanned hospitalizations during cancer therapy

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainAn artificial intelligence (AI) model developed by researchers can predict the likelihood that a patient may have an unp

Updated on: January 04,2024 9

AI model using daily step counts predicts unplanned hospitalizations during cancer therapy

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainAn artificial intelligence (AI) model developed by researchers can predict the likelihood that a patient may have an unp

Updated on:January 04,2024 9

New lease on life for two lung cancer patients after pioneering double-lung transplant

by Cara MurezRetired nurse Tannaz Ameli was diagnosed with stage 4 lung cancer last winter. When chemotherapy failed, her doctors recommended hospice care.But Ameli, of Minneapolis, had other ideas. S

Updated on: December 28,2023 10

New lease on life for two lung cancer patients after pioneering double-lung transplant

by Cara MurezRetired nurse Tannaz Ameli was diagnosed with stage 4 lung cancer last winter. When chemotherapy failed, her doctors recommended hospice care.But Ameli, of Minneapolis, had other ideas. S

Updated on:December 28,2023 10

Automated detection of eye surface cancer

by ARC Centre of Excellence for Nanoscale BioPhotonicsA new automated non-invasive technique for diagnosing eye disease. Credit: ARC Centre of Excellence for Nanoscale BioPhotonicsResearchers hav

Updated on: May 25,2024 4

Automated detection of eye surface cancer

by ARC Centre of Excellence for Nanoscale BioPhotonicsA new automated non-invasive technique for diagnosing eye disease. Credit: ARC Centre of Excellence for Nanoscale BioPhotonicsResearchers hav

Updated on:May 25,2024 4