Pediatric multicenter study shows targeted therapy for high-risk Hodgkin lymphoma reduces relapse

byEmory UniversityHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0A targeted therapy for children with high-risk Hodgkin l

Updated on: December 21,2023 10

Pediatric multicenter study shows targeted therapy for high-risk Hodgkin lymphoma reduces relapse

byEmory UniversityHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0A targeted therapy for children with high-risk Hodgkin l

Updated on:December 21,2023 10

Survivors of childhood cancer have infection complications years after diagnosis

by Gina Bazer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainInfectious complications continue to affect survivors of childhood cancer many years after initial diagnosis, according to f

Updated on: December 21,2023 10

Survivors of childhood cancer have infection complications years after diagnosis

by Gina Bazer,Northwestern UniversityCredit: Pixabay/CC0 Public DomainInfectious complications continue to affect survivors of childhood cancer many years after initial diagnosis, according to f

Updated on:December 21,2023 10

Symptom self-monitoring for childhood cancer survivors—what are oncologists' views?

byKing's College LondonCredit: Unsplash/CC0 Public DomainA new international survey, led by the Stanford University Department of Anesthesiology, Perioperative, and Pain Medicine, and the In

Updated on: December 21,2023 10

Symptom self-monitoring for childhood cancer survivors—what are oncologists' views?

byKing's College LondonCredit: Unsplash/CC0 Public DomainA new international survey, led by the Stanford University Department of Anesthesiology, Perioperative, and Pain Medicine, and the In

Updated on:December 21,2023 10

Pediatric early warning systems for children with cancer a success in Latin American Hospitals

byWileyCredit: Pixabay/CC0 Public DomainPediatric Early Warning Systems (PEWS)—bedside tools used by nurses to assess the health of hospitalized children and identify urgent medical issues—are n

Updated on: December 21,2023 10

Pediatric early warning systems for children with cancer a success in Latin American Hospitals

byWileyCredit: Pixabay/CC0 Public DomainPediatric Early Warning Systems (PEWS)—bedside tools used by nurses to assess the health of hospitalized children and identify urgent medical issues—are n

Updated on:December 21,2023 10

Pharmacotyping of childhood leukemia provides a blueprint for 'true precision medicine'

bySt. Jude Children's Research HospitalWenjian Yang, Shawn Lee, MBBS, and Jun J. Yang, PhD, recently published a comprehensive study pharmacotyping childhood leukemia. Credit: St. Jude Child

Updated on: December 21,2023 10

Pharmacotyping of childhood leukemia provides a blueprint for 'true precision medicine'

bySt. Jude Children's Research HospitalWenjian Yang, Shawn Lee, MBBS, and Jun J. Yang, PhD, recently published a comprehensive study pharmacotyping childhood leukemia. Credit: St. Jude Child

Updated on:December 21,2023 10

Splicing deregulation detected and targeted in type of childhood leukemia

byUniversity of California - San DiegoA micrograph depicts acute myeloid leukemia cells. Though treatments have dramatically advanced, AML in children can become resistant to therapy. New resear

Updated on: December 21,2023 10

Splicing deregulation detected and targeted in type of childhood leukemia

byUniversity of California - San DiegoA micrograph depicts acute myeloid leukemia cells. Though treatments have dramatically advanced, AML in children can become resistant to therapy. New resear

Updated on:December 21,2023 10

Survival rates high for children, teens with melanoma

by Lori SolomonSurvival rates for children and adolescents with melanomas are high, according to a study published online Dec. 9 in theJournal of the American Academy of Dermatology.Mary-Ann El

Updated on: December 21,2023 9

Survival rates high for children, teens with melanoma

by Lori SolomonSurvival rates for children and adolescents with melanomas are high, according to a study published online Dec. 9 in theJournal of the American Academy of Dermatology.Mary-Ann El

Updated on:December 21,2023 9

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on: December 21,2023 7

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on:December 21,2023 7

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,

Updated on: December 21,2023 10

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,

Updated on:December 21,2023 10

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on: December 21,2023 13

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on:December 21,2023 13

Discovery explains cancer chemotherapy resistance, offers solution

byCornell UniversityGraphical abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.08.028Researchers have uncovered a novel pathway that explains how cancer cells become

Updated on: December 21,2023 4

Discovery explains cancer chemotherapy resistance, offers solution

byCornell UniversityGraphical abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.08.028Researchers have uncovered a novel pathway that explains how cancer cells become

Updated on:December 21,2023 4

Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t

Updated on: December 21,2023 10

Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t

Updated on:December 21,2023 10