Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on: January 23,2024 16

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on:January 23,2024 16

Novobiocin attacks BRCA-mutated cancer cells from within and without, study shows

byDana-Farber Cancer InstituteEfficacy of POLθ inhibition in HR-deficient cancers requires CD8+T cells.a,bK14-Cre-Brca1f/f;Trp53f/fTNBC tumors from syngeneic FVB/12

Updated on: January 23,2024 15

Novobiocin attacks BRCA-mutated cancer cells from within and without, study shows

byDana-Farber Cancer InstituteEfficacy of POLθ inhibition in HR-deficient cancers requires CD8+T cells.a,bK14-Cre-Brca1f/f;Trp53f/fTNBC tumors from syngeneic FVB/12

Updated on:January 23,2024 15

Platinum-based chemotherapy distribution within a tumor may predict ovarian cancer treatment resistance

byNagoya UniversityTumor tissue is indicated with the filled arrow and stroma with the unfilled arrow (upper photo).A platinum-resistant patient showing platinum (blue in the bottom photo) mostl

Updated on: January 22,2024 19

Platinum-based chemotherapy distribution within a tumor may predict ovarian cancer treatment resistance

byNagoya UniversityTumor tissue is indicated with the filled arrow and stroma with the unfilled arrow (upper photo).A platinum-resistant patient showing platinum (blue in the bottom photo) mostl

Updated on:January 22,2024 19

Substance use disorders on the rise for survivors of specific cancers

by Elana GotkineThe prevalence of substance use disorder (SUD) seems to be elevated among survivors of certain types of cancer, according to a study published online Jan. 11 inJAMA Oncology.Kati

Updated on: March 05,2024 16

Substance use disorders on the rise for survivors of specific cancers

by Elana GotkineThe prevalence of substance use disorder (SUD) seems to be elevated among survivors of certain types of cancer, according to a study published online Jan. 11 inJAMA Oncology.Kati

Updated on:March 05,2024 16

Race/ethnicity, socioeconomics, age contribute to disparities in cancer death

by Elana GotkineFactors contributing to disparities in cancer death include race/ethnicity, socioeconomic status, geographic location, and age, according to a study published online Nov. 14 inCA

Updated on: April 07,2024 19

Race/ethnicity, socioeconomics, age contribute to disparities in cancer death

by Elana GotkineFactors contributing to disparities in cancer death include race/ethnicity, socioeconomic status, geographic location, and age, according to a study published online Nov. 14 inCA

Updated on:April 07,2024 19

It's all about quality: Effect of dietary fat composition on liver angiogenesis and lymphangiogenesis

by Shinshu UniversityIn a new study, scientists from Japan demonstrate that saturated/trans fats in the diet, and not cholesterol, promote hepatic angiogenesis and lymphangiogenesis and thereby trigge

Updated on: February 23,2024 15

It's all about quality: Effect of dietary fat composition on liver angiogenesis and lymphangiogenesis

by Shinshu UniversityIn a new study, scientists from Japan demonstrate that saturated/trans fats in the diet, and not cholesterol, promote hepatic angiogenesis and lymphangiogenesis and thereby trigge

Updated on:February 23,2024 15

Drug combination for stage IV melanoma shows success in trial

by CU Anschutz Medical CampusMelanoma. Credit: Wikimedia Commons/National Cancer InstituteA new multidrug treatment for patients with stage IV melanoma has proven effective after a three-year cli

Updated on: February 23,2024 19

Drug combination for stage IV melanoma shows success in trial

by CU Anschutz Medical CampusMelanoma. Credit: Wikimedia Commons/National Cancer InstituteA new multidrug treatment for patients with stage IV melanoma has proven effective after a three-year cli

Updated on:February 23,2024 19

Proton therapy lowers treatment side effects in pediatric head and neck cancer patients

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainPediatric patients with head and neck cancer can be treated with proton beam therapy (PBT) instead of trad

Updated on: April 10,2024 17

Proton therapy lowers treatment side effects in pediatric head and neck cancer patients

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainPediatric patients with head and neck cancer can be treated with proton beam therapy (PBT) instead of trad

Updated on:April 10,2024 17

Researchers identify a gene as a potential target in treatment-resistant brain cancer glioblastoma multiforme

by University of California, Los AngelesSingle-cell sequencing reveals the diverse functional states of glioma cells post-radiation.aUMAP plot of cell clusters from control (0 Gy) and

Updated on: February 23,2024 19

Researchers identify a gene as a potential target in treatment-resistant brain cancer glioblastoma multiforme

by University of California, Los AngelesSingle-cell sequencing reveals the diverse functional states of glioma cells post-radiation.aUMAP plot of cell clusters from control (0 Gy) and

Updated on:February 23,2024 19

Test can predict how people with leukaemia will respond to chemotherapy

by BloodwiseCredit: CC0 Public DomainThe first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukaemia has been developed at Cardiff

Updated on: April 18,2024 19

Test can predict how people with leukaemia will respond to chemotherapy

by BloodwiseCredit: CC0 Public DomainThe first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukaemia has been developed at Cardiff

Updated on:April 18,2024 19

New smoking cessation intervention helps patients with cervical cancer precursor or cervical cancer quit smoking

byH. Lee Moffitt Cancer Center & Research InstituteCredit: CC0 Public DomainTobacco use is the leading preventable cause of death in the U.S., accounting for about 1 in 5 deaths each y

Updated on: January 12,2024 10

New smoking cessation intervention helps patients with cervical cancer precursor or cervical cancer quit smoking

byH. Lee Moffitt Cancer Center & Research InstituteCredit: CC0 Public DomainTobacco use is the leading preventable cause of death in the U.S., accounting for about 1 in 5 deaths each y

Updated on:January 12,2024 10

Aromatherapy and reflexology ease side effects for cancer patients

by Amanda Harper,The Ohio State UniversityCredit: CC0 Public DomainA noninvasive approach using aromatherapy and reflexology can dramatically reduce pain and anxiety for women undergoing cervica

Updated on: April 14,2024 19

Aromatherapy and reflexology ease side effects for cancer patients

by Amanda Harper,The Ohio State UniversityCredit: CC0 Public DomainA noninvasive approach using aromatherapy and reflexology can dramatically reduce pain and anxiety for women undergoing cervica

Updated on:April 14,2024 19